1053 Results for "

Tert

" in MedChemExpress (MCE) Product Catalog:
Products (1053)

1053 Results for "Tert" in MCE Product Catalog:

129
129 Publications Verification
Cat. No.: HY-100489
CAS No.: 1948-33-0
Purity:  99.89%
Synonyms: Tert-Butylhydroquinone
TBHQ (tert-Butylhydroquinone) is a widely used Nrf2 activator, protects against Doxorubicin (DOX)-induced cardiotoxicity through activation of Nrf2 . TBHQ (tert-Butylhydroquinone) is also an ERK activator; rescues Dehydrocorydaline (DHC)-induced cell proliferation inhibitionin melanoma .
loading...
    loading...
28
28 Cited Publications
Cat. No.: HY-Y1883A
CAS No.: 9002-93-1
Polyethylene glycol mono(4-tert-octylphenyl) ether is a non-denaturing detergent that solubilizes lipid membranes. Polyethylene glycol mono(4-tert-octylphenyl) ether is commonly used in laboratories and is applied to vaccines at different stages of the manufacturing process. Polyethylene glycol mono(4-tert-octylphenyl) ether is listed as an excipient in certain vaccines including split virus influenza vaccines. Polyethylene glycol mono(4-tert-octylphenyl) ether is a nonionic surfactant. Polyethylene glycol mono(4-tert-octylphenyl) ether induces Apoptosis in prostate and colon cancer cell lines and reduces the infectivity of classic enveloped viruses such as WNV .
loading...
    loading...
28
28 Cited Publications
Cat. No.: HY-Y1883
CAS No.: 9002-93-1
Polyethylene glycol mono(4-tert-octylphenyl) ether surfactant is a non-denaturing detergent that solubilizes lipid membranes. Polyethylene glycol mono(4-tert-octylphenyl) ether surfactant is commonly used in laboratories and is applied to vaccines at different stages of the manufacturing process. Polyethylene glycol mono(4-tert-octylphenyl) ether surfactant is listed as an excipient in certain vaccines including split virus influenza vaccines. Polyethylene glycol mono(4-tert-octylphenyl) ether surfactant is a nonionic surfactant. Polyethylene glycol mono(4-tert-octylphenyl) ether surfactant induces Apoptosis in prostate and colon cancer cell lines and reduces the infectivity of classic enveloped viruses such as WNV .
loading...
    loading...
26
26 Cited Publications
Cat. No.: HY-135146
CAS No.: 2170136-65-7
Purity:  99.95%
Synonyms: (R)-GSK3482364
Research Areas:  

Cancer

GSK-3484862 is a highly potent non-covalent inhibitor and demethylating agent of DNMT1. GSK-3484862 induces genome-wide DNA demethylation, including the regulatory elements of DNMT3B and the promoter region of TERT, and significantly inhibits cell viability, growth, proliferation and self-renewal. GSK-3484862 blocks the transformation of young AT2 cells, induces apoptosis, and generates transcriptomic features similar to those of senescent cells. GSK-3484862 is widely used in studies related to lung cancer, oral squamous cell carcinoma and lung adenocarcinoma .
loading...
    loading...
8
8 Cited Publications
Cat. No.: HY-B0130A
CAS No.: 107133-36-8
Synonyms: Perindopril (Tert-butylamine salt); S-9490 erbumine
Perindopril erbumine is an angiotensin-converting enzyme inhibitor. Perindopril erbumine modulates NF-κB and STAT3 signaling and inhibits glial activation and neuroinflammation. Perindopril erbumine can be used for the research of Chronic Kidney Disease and high blood pressure .
loading...
    loading...
3
3 Cited Publications
Cat. No.: HY-128463
CAS No.: 3376-24-7
Purity:  99.94%
N-tert-Butyl-α-phenylnitrone is a nitrone-based free radical scavenger that forms nitroxide spin adducts. N-tert-Butyl-α-phenylnitrone inhibits COX2 catalytic activity. N-tert-Butyl-α-phenylnitrone has potent ROS scavenging, anti-inflammatory, neuroprotective, anti-aging and anti-diabetic activities, and can penetrate the blood-brain barrier .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-B1941
CAS No.: 140-66-9
4-tert-Octylphenol, a endocrine-disrupting chemical, is an estrogenic agent. 4-tert-Octylphenol is also a biodegradation product of non-ionic surfactants alkylphenol polyethoxylates. 4-tert-Octylphenol induces apoptosis in neuronal progenitor cells in offspring mouse brain. 4-tert-Octylphenol reduces bromodeoxyuridine (BrdU), mitotic marker Ki67, and phospho-histone H3 (p-Histone-H3), resulting in a reduction of neuronal progenitor proliferation. 4-tert-Octylphenol disrupts brain development and behavior in mice, which is promising for reserch of immune response, neuro-related diseases and ethology .
loading...
    loading...
2
2 Cited Publications
Cat. No.: HY-W014589
CAS No.: 96-76-4
Synonyms: 2,4-DTBP
2,4-Di-tert-butylphenol (2,4-DTBP) is an orally active RXRα activator and a human estrogen receptor ligand with anti-inflammatory and antioxidant activities, which can induce apoptosis in tumor cells. 2,4-Di-tert-butylphenol can activate the RXRα subtype in LXRα/RXRα, PPARγ/RXRα, and hormone receptor β/RXRα. 2,4-Di-tert-butylphenol also has antiviral and antifungal activities and has the potential to inhibit -induced neurotoxicity. 2,4-Di-tert-butylphenol can be used as an intermediate in the preparation of antioxidants and UV stabilizers, and is also used in the manufacture of drugs and fragrances .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-100489R
CAS No.: 1948-33-0
Purity:  99.86%
Synonyms: Tert-Butylhydroquinone (Standard)
TBHQ (Standard) is the analytical standard of TBHQ. This product is intended for research and analytical applications. TBHQ (tert-Butylhydroquinone) is a widely used Nrf2 activator, protects against Doxorubicin (DOX)-induced cardiotoxicity through activation of Nrf2 . TBHQ (tert-Butylhydroquinone) is also an ERK activator; rescues Dehydrocorydaline (DHC)-induced cell proliferation inhibitionin melanoma .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-103502
CAS No.: 57717-80-3
Purity:  ≥99.0%
Target:  

GABA Receptor

Research Areas:  

Neurological Disease

CGP7930 (3-(3’,5’-Di-tert-butyl-4’-hydroxy) phenyl-2, 2-dimethylpropanol) is a positive metabotropic GABAB receptor allosteric modulator. CGP7930 enhances the inhibitory effect of l-baclofen on the oscillatory activity of cultured cortical neurons .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-W017330
CAS No.: 760-93-0
Research Areas:  

Others

Methacrylic anhydride is a typical polymerizable 1,6-diolefin. Methacrylic anhydride can form a soluble csyclopolymer by free-radical initiation. Methacrylic anhydride can spontaneously polymerize through the vinyl group and justifies the use of 2-6-di-tert-butyl4-methylphenol as an inhibitor .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-159059
Purity:  41.20%
Ganoderma Lucidum/Reishi Extract is a Ganoderma lucidum extract. Ganoderma Lucidum/Reishi Extract reduces the expression of c-Myc, BCL-2, BCL-XL, TERT, PDGFB, eIF4G, Survivin, β-catenin, and eIF4E. Ganoderma Lucidum/Reishi Extract downregulates the gene expression of MMP-9. Ganoderma Lucidum/Reishi Extract upregulates the expression of IL8. Ganoderma Lucidum/Reishi Extract is applicable to the research of inflammatory breast cancer. Ganoderma Lucidum is used in the research of various diseases, such as allergy, arthritis, hypertension, neurasthenia, inflammation, and cancer .
loading...
    loading...
1
1 Cited Publications
Cat. No.: HY-41982
CAS No.: 32449-92-6
Synonyms: D-Glucurono-6,3-lactone; D-Glucurono-γ-lactone; D-Glucuronolactone; Dicurone; Glucoxy; Glucurolactone; Glucurone
D-Glucuronic acid lactone (D-Glucurono-6,3-lactone; D-Glucurono-γ-lactone; D-Glucuronolactone; Dicurone; Glucoxy; Glucurolactone; Glucurone) is an endogenous metabolite and a glucuronic acid derivative. D-Glucuronic acid lactone serves as a starting reagent for the synthesis of 2,3,4-tris (tert-butyldimethylsilyl) glucuronic acid trichloroethyl ester, which is used to prepare 1-O-acyl glucuronic acids for the anti-inflammatory agent mL-3000 (HY-B1452), synthesize optically active glucuronic acids, and produce long-chain alkyl glucuronides. D-Glucuronic acid lactone shows potential for use in studies of reversible cerebral vasoconstriction syndrome (RCVS) .
loading...
    loading...
Cat. No.: HY-W054292
CAS No.: 1025796-31-9
Synonyms: (OtBu)KuE(OtBu)2
Tert-Butyl-DCL is a PSMA inhibitor. Tert-Butyl-DCL Tert-Butyl-DCL can be used in the research of prostate cancer .
loading...
    loading...
Cat. No.: HY-W007408
CAS No.: 6456-74-2
Research Areas:  

Others

tert-Butyl 2-aminoacetate is a Glycine (HY-Y0966) derivative .
loading...
    loading...
Cat. No.: HY-W038703
CAS No.: 70396-18-8
Research Areas:  

Others

(tert-Butoxycarbonyl)-L-valyl-L-alanine is an alanine derivative .
loading...
    loading...
Cat. No.: HY-402361
CAS No.: 666699-46-3
Target:  

MEK ERK AP-1

TERT activator-1 is a small molecule activator of telomerase reverse transcriptase (TERT). TERT activator-1 promotes TERT transcription through the MEK/ERK/AP-1 signaling cascade. TERT activator-1 promotes adult neurogenesis and enhances neuromuscular function. TERT activator-1 reduces cellular senescence and systemic inflammation in aged mice, and can be used in the study of aging .
loading...
    loading...
Cat. No.: HY-W002294
CAS No.: 6368-20-3
Research Areas:  

Others

(tert-Butoxycarbonyl)-D-serine is a serine derivative .
loading...
    loading...
Cat. No.: HY-Y0373
CAS No.: 870-46-2
Research Areas:  

Infection

tert-Butyl carbazate serves as a starting material for the preparation of heterocyclic and hydrazine derivatives. tert-Butyl carbazate undergoes coupling with aryl, heteroaryl, and alkenyl boronic acids to synthesize doubly protected monosubstituted hydrazines. Derivatives of tert-Butyl carbazate exhibit varying degrees of inhibitory activity against Gram-positive bacteria, Gram-negative bacteria, and various fungi .
loading...
    loading...
Cat. No.: HY-34415
CAS No.: 110661-91-1
Synonyms: Tert-Butyl 4-Bromobutyrate
Target:  

PROTAC Linkers

Research Areas:  

Cancer

4-Bromobutanoic acid tert-butyl ester (tert-Butyl 4-Bromobutyrate) is a PROTAC linker that can be used in the synthesis of PROTACs.
loading...
    loading...