96-76-4
96-76-4
Chemical Structure
2,4-Di-tert-butylphenol
Synonym(s): 2,4-DTBP
- CAS No.: 96-76-4
- Formula:C14H22O
- Molecular Weight:206.33
IUPAC Name: 2,4-di-tert-butylphenol
InChIKey: ICKWICRCANNIBI-UHFFFAOYSA-N
SMILES: OC1=CC=C(C(C)(C)C)C=C1C(C)(C)C
Biological Activity: 2,4-Di-tert-butylphenol (2,4-DTBP) is an orally active RXRα activator and a human estrogen receptor ligand with anti-inflammatory and antioxidant activities, which can induce apoptosis in tumor cells. 2,4-Di-tert-butylphenol can activate the RXRα subtype in LXRα/RXRα, PPARγ/RXRα, and hormone receptor β/RXRα. 2,4-Di-tert-butylphenol also has antiviral and antifungal activities and has the potential to inhibit Aβ-induced neurotoxicity. 2,4-Di-tert-butylphenol can be used as an intermediate in the preparation of antioxidants and UV stabilizers, and is also used in the manufacture of drugs and fragrances[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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2,4-Di-tert-butylphenol | 99.93% | 2,4-Di-tert-butylphenol (2,4-DTBP) is an orally active RXRα activator and a human estrogen receptor ligand with anti-inflammatory and antioxidant activities, which can induce apoptosis in tumor cells. 2,4-Di-tert-butylphenol can activate the RXRα subtype in LXRα/RXRα, PPARγ/RXRα, and hormone receptor β/RXRα. 2,4-Di-tert-butylphenol also has antiviral and antifungal activities and has the potential to inhibit Aβ-induced neurotoxicity. 2,4-Di-tert-butylphenol can be used as an intermediate in the preparation of antioxidants and UV stabilizers, and is also used in the manufacture of drugs and fragrances. | ||||||||||||||||||||
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2,4-Di-tert-butylphenol (Standard) | 99.67% | 2,4-Di-tert-butylphenol (Standard) is the analytical standard of 2,4-Di-tert-butylphenol (HY-W014589). This product is intended for research and analytical applications. 2,4-Di-tert-butylphenol (2,4-DTBP) is an orally active RXRα activator and a human estrogen receptor ligand with anti-inflammatory and antioxidant activities, which can induce apoptosis in tumor cells. 2,4-Di-tert-butylphenol can activate the RXRα subtype in LXRα/RXRα, PPARγ/RXRα, and hormone receptor β/RXRα. 2,4-Di-tert-butylphenol also has antiviral and antifungal activities, and has the potential to inhibit Aβ-induced neurotoxicity. 2,4-Di-tert-butylphenol can be used as an intermediate in the preparation of antioxidants and UV stabilizers, and is also used in the manufacture of pharmaceuticals and fragrances. | ||||||||||||||||||||
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2,4-Di-tert-butylphenol-d19 | 2,4-Di-tert-butylphenol-d19 (2,4-DTBP-d19) is the deuterium labeled 2,4-Di-tert-butylphenol (HY-W014589). 2,4-Di-tert-butylphenol (2,4-DTBP) is an orally active RXRα activator and a human estrogen receptor ligand with anti-inflammatory and antioxidant activities, which can induce apoptosis in tumor cells. 2,4-Di-tert-butylphenol can activate the RXRα subtype in LXRα/RXRα, PPARγ/RXRα, and hormone receptor β/RXRα. 2,4-Di-tert-butylphenol also has antiviral and antifungal activities and has the potential to inhibit Aβ-induced neurotoxicity. 2,4-Di-tert-butylphenol can be used as an intermediate in the preparation of antioxidants and UV stabilizers, and is also used in the manufacture of drugs and fragrances. | |||||||||||||||||||||
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2,4-Di-tert-butylphenol-d21 | 92.26% | 2,4-Di-tert-butylphenol-d21 (2,4-DTBP-d21) is the deuterium labeled 2,4-Di-tert-butylphenol (HY-W014589). 2,4-Di-tert-butylphenol (2,4-DTBP) is an orally active RXRα activator and a human estrogen receptor ligand with anti-inflammatory and antioxidant activities, which can induce apoptosis in tumor cells. 2,4-Di-tert-butylphenol can activate the RXRα subtype in LXRα/RXRα, PPARγ/RXRα, and hormone receptor β/RXRα. 2,4-Di-tert-butylphenol also has antiviral and antifungal activities and has the potential to inhibit Aβ-induced neurotoxicity. 2,4-Di-tert-butylphenol can be used as an intermediate in the preparation of antioxidants and UV stabilizers, and is also used in the manufacture of drugs and fragrances. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.89
HY-W0410803,5-Di-tert-butylphenol -
Similarity Score 0.84
HY-W0870581,4-Di-tert-butylbenzene -
Similarity Score 0.82
HY-100489TBHQ -
Similarity Score 0.81
HY-W0100372-(tert-Butyl)-4-methoxyphenol -
Similarity Score 0.80
HY-Y07163-t-Butylphenol -
Similarity Score 0.79
HY-B1941R4-tert-Octylphenol (Standard) -
Similarity Score 0.79
HY-B1941S14-tert-Octylphenol-13C6 -
Similarity Score 0.79
HY-W024365R3-tert-Butyl-4-methoxyphenol (Standard) -
Similarity Score 0.78
HY-W0165892-(tert-Butyl)-4,6-dimethylphenol -
Explore the MedChemAI to find more analogs
References
- [1]. Zhao F, et al. Natural sources and bioactivities of 2, 4-di-tert-butylphenol and its analogs[J]. Toxins, 2020, 12(1): 35. [Content Brief]
- [2]. Ren XM, et al. 2,4-Di-tert-butylphenol Induces Adipogenesis in Human Mesenchymal Stem Cells by Activating Retinoid X Receptors. Endocrinology. 2023 Feb 11;164(4):bqad021. [Content Brief]
- [3]. Choi SJ, et al. 2,4-Di-tert-butylphenol from sweet potato protects against oxidative stress in PC12 cells and in mice. J Med Food. 2013 Nov;16(11):977-83. [Content Brief]
