109 Results for "

Type IV

" in MedChemExpress (MCE) Product Catalog:
Products (109)

109 Results for "Type IV" in MCE Product Catalog:

20
20 Publications Verification
Referencia número: HY-E70005D
No. CAS: 9001-12-1
Synonyms: Collagenase, Type IV
Target:  

MMP

Áreas de investigación:  

Others

Collagenase, Type IV (EC 3.4.24.3) is a microbially derived matrix metalloproteinases (MMPs) and zinc peptidase. Collagenase, Type IV degrades type IV collagen and type VII collagen, the main components of the basement membrane, and can also decompose basement matrix and elastin.

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12
12 Cited Publications
Referencia número: HY-16742B
No. CAS: 1624306-20-2
Áreas de investigación:  

Infection

Gepotidacin mesylate hydrate is an orally active triazaacenaphthylene antibiotic and bacterial type II topoisomerase inhibitor. Gepotidacin mesylate hydrate inhibits bacterial DNA replication by blocking topoisomerase enzymes. Gepotidacin mesylate hydrate selectively inhibits topoisomerase IV and the B subunit of DNA gyrase .
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9
9 Cited Publications
Referencia número: HY-P73296
Pureza:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: 72 kDa Type IV Collagenase; Gelatinase A; MMP-2; TBE-1; CLG4A
Species:  
Source:  
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6
6 Cited Publications
Referencia número: HY-131577
No. CAS: 42613-33-2
Synonyms: Dispase II, Dispase
Neutral protease, Paenibacillus polymyxa (Dispase II, Dispase) is a neutral protease and potent fibronectinase and type IV collagenase. Neutral protease, Paenibacillus polymyxa can be used to separate the intact epidermis from the dermis and intact epithelial sheets in culture from the substratum .
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6
6 Cited Publications
Referencia número: HY-P81227
Synonyms: Collagen Type I; Alpha 1 Type I collagen; Alpha 2 Type I collagen; COL1A1; COL1A2; Collagen I alpha 1 polypeptide; Collagen I alpha 2 polypeptide; Collagen Of Skin Tendon And Bone; Collagen Type 1; Collagen Type I alpha 1; Collagen Type I alpha 2; OI4; Osteogenesis Imperfecta Type IV; Pro alpha 1(I) collagen; Type I procollagen; CO1A1_HUMAN.

Host:  

Rabbit

Application:  

WB, IHC-P

Reactivity:  

Human, Mouse, Rat, Rabbit

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4
4 Cited Publications
Referencia número: HY-10581
No. CAS: 112811-59-3
Pureza:  99.69%
Synonyms: AM-1155; BMS-206584; PD135432
Áreas de investigación:  

Infection Neurological Disease Cancer

Gatifloxacin (AM-1155; BMS-206584; PD135432) is a potent fluoroquinolone antibiotic that can cross the blood-brain barrier, with broad-spectrum antibacterial activity. Gatifloxacin inhibits bacterial type II topoisomerases (IC50=13.8 μg/ml for S. aureus topoisomerase IV) and E. coli DNA gyrase (IC50=0.109 μg/ml) . Gatifloxacin can be used to treat bacterial conjunctivitis in vivo.
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4
4 Cited Publications
Referencia número: HY-P1408
No. CAS: 404882-00-4
Target:  

Integrin VEGFR

Áreas de investigación:  

Cancer

Obtustatin is a non-RGD disintegrin consisting of 41 residues. Obtustatin inhibits the adhesion of α1β1 integrin to type IV Collagen (HY-NP003), blocks α1β1 integrin signaling in endothelial cells, and suppresses FGF2-induced angiogenesis. Obtustatin inhibits tumor progression in mouse models and upregulates VEGF expression in sarcoma-bearing mice. Obtustatin can be used in research related to Lewis lung carcinoma and S-180 sarcoma .
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4
4 Cited Publications
Referencia número: HY-10581A
No. CAS: 121577-32-0
Pureza:  99.89%
Synonyms: AM-1155 hydrochloride; BMS-206584 hydrochloride; PD135432 hydrochloride
Áreas de investigación:  

Infection

Gatifloxacin hydrochloride (AM-1155; BMS-206584; PD135432) is a potent fluoroquinolone antibiotic with broad-spectrum antibacterial activity. Gatifloxacin hydrochloride inhibits bacterial type II topoisomerases (IC50=13.8 μg/ml for S. aureus topoisomerase IV) and E. coli DNA gyrase (IC50 = 0.109 μg/ml) . Gatifloxacin hydrochloride can be used to treat bacterial conjunctivitis in vivo.
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4
4 Cited Publications
Referencia número: HY-P1408A
Target:  

Integrin

Áreas de investigación:  

Cancer

Obtustatin triacetate is a 41-residue non-RGD disintegrin. Obtustatin triacetate can be isolated from the venom of Vipera lebetina obtusa. Obtustatin triacetate is a potent and selective inhibitor of integrin α1β1 adhesion to type IV collagen. Obtustatin triacetate inhibits angiogenesis and may be used in cancer research .
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3
3 Cited Publications
Referencia número: HY-P70268
Pureza:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rHu72 kDa Type IV collagenase/MMP-2, His ; 72 kDa Type IV Collagenase; 72 kDa Gelatinase; Gelatinase A; Matrix Metalloproteinase-2; MMP-2; TBE-1; MMP2; CLG4A
Species:  
Source:  
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2
2 Cited Publications
Referencia número: HY-110238
No. CAS: 1062271-24-2
Pureza:  98.27%
Target:  

TRP Channel

Áreas de investigación:  

Metabolic Disease

MK6-83 is a new candidate agonist of TRPML1 with an improved efficacy and potency. MK6-83 has the potential for Mucolipidosis type IV study .
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2
2 Cited Publications
Referencia número: HY-P73810
Pureza:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: 72 kDa Type IV Collagenase; Gelatinase A; MMP-2; TBE-1; CLG4A
Species:  
Source:  
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2
2 Cited Publications
Referencia número: HY-P80756
Synonyms: MMP9; CLG4B; Matrix metalloproteinase-9; MMP-9; 92 kDa gelatinase; 92 kDa Type IV collagenase; Gelatinase B; GELB

Host:  

Rabbit

Application:  

WB, IHC-P, ICC/IF

Reactivity:  

Human, Mouse, Rat

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2
2 Cited Publications
Referencia número: HY-P70351A
Pureza:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rMuMatrix metalloproteinase-9/MMP-9, His; Matrix metalloproteinase-9; MMP-9; 92 kDa gelatinase; 92 kDa Type IV collagenase; Gelatinase B; GELB
Species:  
Source:  
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1
1 Cited Publications
Referencia número: HY-P2975
No. CAS: 114956-81-9
Synonyms: Mouse laminin (Engelbreth-Holm-Swarm murine sarcoma basement membrane)
Laminin (Engelbreth-Holm-Swarm murine sarcoma basement membrane) is a crucial structural element in animal tissues, forming part of the scaffolding that supports tissue architecture. It interacts with type IV collagen through entactin and perlecan, connects to cell membranes via integrin receptors, dystroglycan complexes, and Lutheran blood group glycoproteins, and contains functional domains that facilitate collagen binding, cell adhesion, heparin interaction, and promote neurite outgrowth.
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1
1 Cited Publications
Referencia número: HY-P4633
No. CAS: 7432-23-7
Target:  

Dipeptidyl Peptidase

Áreas de investigación:  

Metabolic Disease

γ-Glu-Tyr, a competitive inhibitor of dipeptidyl peptidase-IV (DPP-IV) (IC50=6.77 mM), is a potentially functional component of the type 2 diabetes diet .
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1
1 Cited Publications
Referencia número: HY-P70990
Pureza:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Protein-Arginine Deiminase Type-4; HL-60 PAD; Peptidylarginine Deiminase IV; Protein-arginine Deiminase Type IV; PADI4; PADI5; PDI5
Species:  
Source:  
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1
1 Cited Publications
Referencia número: HY-P700573
Pureza:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: rHu72 kDa Type IV collagenase/MMP-2, His ; 72 kDa Type IV Collagenase; 72 kDa Gelatinase; Gelatinase A; Matrix Metalloproteinase-2; MMP-2; TBE-1; MMP2; CLG4A
Species:  
Rat
Source:  
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1
1 Cited Publications
Referencia número: HY-P81101
Synonyms: COL 3A1; COL3A1; Collagen alpha 1(III) chain; Collagen III alpha 1 chain precursor; Collagen III alpha 1 polypeptide; Collagen Type III alpha 1 (Ehlers Danlos syndrome Type IV autosomal dominant); Collagen Type III alpha 1; Collagen Type III alpha; EDS4A; Ehlers Danlos syndrome Type IV, autosomal dominant; Fetal collagen; Type III collagen; CO3A1_HUMAN; Collagen alpha-1(III) chain; Type III collagen; Type III preprocollagen alpha 1 chain.

Host:  

Rabbit

Application:  

WB, ELISA, IHC-P, IHC-F, ICC/IF

Reactivity:  

Human, Dog, Rabbit

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1
1 Cited Publications
Referencia número: HY-D1633A
No. CAS: 206443-06-3
4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate sodium is a fluorescent dye. 4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate sodium undergoes desulphation by galactose-6-sulphate sulphatase to form 4-methylumbelliferyl-β-D-galactopyranoside, which is cleaved by β-galactosidase to release fluorescent 4-methylumbelliferone. 4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate sodium interacts with N-acetylgalactosamine-6-sulfate sulfatase (GALNS) via hydrogen bonds, electrostatic interactions, and steric interactions. 4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate sodium serves as a substrate in assays measuring galactose-6-sulphate sulphatase and GALNS activity. 4-Methylumbelliferyl-β-D-galactopyranoside 6-sulfate sodium can be used for the research of Morquio disease type A (mucopolysaccharidosis IV A) .
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