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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
22 Results for "
V1/S
" in MedChemExpress (MCE) Product Catalog:
Products (22)
22 Results for "V1/S" in MCE Product Catalog:
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24 Publications Verification
Cat. No.: HY-N0751
CAS No.: 27740-01-8
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1 Cited Publications
N-Desethyl amodiaquine is the biologically active metabolite of Amodiaquine (HY-B1322A). N-Desethyl amodiaquine is an antiparasitic agent, has inhibitory for strains V1/S and 3D7 with IC50 values of 97 nM and 25 nM, respectively. N-Desethyl amodiaquine can be used for the research of malaria .
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1 Cited Publications
N-Desethyl amodiaquine dihydrochloride is the biologically active metabolite of Amodiaquine (HY-B1322A). N-Desethyl amodiaquine dihydrochloride is an antiparasitic agent, has inhibitory for strains V1/S and 3D7 with IC50 values of 97 nM and 25 nM, respectively. N-Desethyl amodiaquine dihydrochloride can be used for the research of malaria .
Cat. No.: HY-P1737
CAS No.: 111317-90-9
Synonyms: Con-S
Target:
Research Areas:
Cat. No.: HY-128554AR
CAS No.: 79049-30-2
Target:
Research Areas:
N-Desethyl amodiaquine dihydrochloride (Standard) is the analytical standard of N-Desethyl amodiaquine dihydrochloride. This product is intended for research and analytical applications. N-Desethyl amodiaquine dihydrochloride is the biologically active metabolite of Amodiaquine (HY-B1322A). N-Desethyl amodiaquine dihydrochloride is an antiparasitic agent, has inhibitory for strains V1/S and 3D7 with IC50 values of 97 nM and 25 nM, respectively. N-Desethyl amodiaquine dihydrochloride can be used for the research of malaria .
Cat. No.: HY-168069
Research Areas:
DHFR-IN-20 (Compound LA1) is a Plasmodium falciparum dihydrofolate reductase (DHFR) inhibitor, with Kis of 0.16, 0.30, 6.6 nM for PfDHFR-WT, PfDHFR-QM, HsDHFR. DHFR-IN-20 has antimalarial activities (IC50: 1.4 nM and 1.6 μM for P. falciparum carrying the wild-type (TM4/8.2) and the quadruple mutant (V1/S) PfDHFR enzyme .
Cat. No.: HY-N0751R
CAS No.: 27740-01-8
Target:
Cat. No.: HY-170911
KIT/PDGFRA-IN-1 (compound 19) is a stem cell growth factor receptor (KIT) and platelet-derived growth factor receptor alpha (PDGFRA) inhibitor. KIT/PDGFRA-IN-1 inhibits KIT-wt, KIT-D816H, KIT-T670I, PDGFRA-wt, PDGFRA-D842V, PDGFRA-T674I and PDGFRA-G680R with IC50s of 2.3, 12, 492, 0.8, 99.9, 42.3, and 4.3 μM, respectively. KIT/PDGFRA-IN-1 inhibits GIST-T1, T1-a-D842V and GIST-48B cells (PDGFR- and KIT-Mutant GIST cell Lines) with GR50s of 12, 8900, ≥10 000 nM, respectively .
Cat. No.: HY-P5439
Research Areas:
(S,R,S)-AHPC-PEG5-Boc is a E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used for Cdc20 degrader CP5V .
Cat. No.: HY-106017
CAS No.: 119229-65-1
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Research Areas:
Nerispirdine is an ion channel inhibitor with IC50s of 3.6, 3.7 and 11.9 μM against K(v)1.1, K(v)1.2 and voltage-dependent Na(+) channel, respectively. Nerispirdine is a 4-aminopyridine (4-AP, HY-B0604) derivative and can be utilized in research on neurological disorders .
Cat. No.: HY-N17304
CAS No.: 314744-17-7
Target:
Cat. No.: HY-P76159A
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: ATP6V1F; Vacuolar Proton Pump Subunit F; ATPase H+ Transporting V1 Subunit F; V-ATPase 14 KDa Subunit; ATP6S14; H(+)-Transporting Two-Sector ATPase, 14kD Subunit; VATF; Adenosinetriphosphatase 14k Chain; V-Type Proton ATPase Subunit F; Vacuolar ATP Syntha
Cat. No.: HY-P76159
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: ATP6V1F; Vacuolar Proton Pump Subunit F; ATPase H+ Transporting V1 Subunit F; V-ATPase 14 KDa Subunit; ATP6S14; H(+)-Transporting Two-Sector ATPase, 14kD Subunit; VATF; Adenosinetriphosphatase 14k Chain; V-Type Proton ATPase Subunit F; Vacuolar ATP Syntha
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
