2751718-88-2
2751718-88-2
Chemical Structure
SOS1-IN-6
- CAS No.: 2751718-88-2
- Formula:C26H28F3N3O2
- Molecular Weight:471.51
IUPAC Name: (1R,4r)-4-(4-(((R)-1-(3-(difluoromethyl)-2-fluorophenyl)ethyl)amino)-2-methyl-8,9-dihydrofuro[2,3-h]quinazolin-6-yl)cyclohexan-1-ol
InChIKey: SHKRNXVJKPJIKE-FVQBIDKESA-N
SMILES: O[C@H]1CC[C@H](C2=CC3=C(N[C@@H](C4=CC=CC(C(F)F)=C4F)C)N=C(C)N=C3C5=C2OCC5)CC1
Biological Activity: SOS1-IN-6 (compound 33-P1) is a potent SOS1 inhibitor with IC50s of 14.9 and 73.3 nM for SOS1-G12D and SOS1-G12V, respectively[1].
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SOS1-IN-6 | SOS1-IN-6 (compound 33-P1) is a potent SOS1 inhibitor with IC50s of 14.9 and 73.3 nM for SOS1-G12D and SOS1-G12V, respectively. | |||||||||||||||||||||
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