2755415-30-4
2755415-30-4
Chemical Structure
SOS1-IN-7
- CAS No.: 2755415-30-4
- Formula:C23H25F3N4O3
- Molecular Weight:462.46
IUPAC Name: 4-(((R)-1-(3-(difluoromethyl)-2-fluorophenyl)ethyl)amino)-6-((1s,4S)-1,4-dihydroxycyclohexyl)-2-methylpyrido[2,3-d]pyrimidin-7(1H)-one
InChIKey: TWVXXNYGWUGIAX-JCRSYGSLSA-N
SMILES: C[C@H](C1=C(C(C(F)F)=CC=C1)F)NC2=C3C(NC(C)=N2)=NC(C([C@@]4(CC[C@H](CC4)O)O)=C3)=O
Biological Activity: SOS1-IN-7 (compound 18-p1) is a potent SOS1 inhibitor with IC50s of 20 and 67 nM for SOS1-G12D and SOS1-G12V, respectively[1].
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SOS1-IN-7 | SOS1-IN-7 (compound 18-p1) is a potent SOS1 inhibitor with IC50s of 20 and 67 nM for SOS1-G12D and SOS1-G12V, respectively. | |||||||||||||||||||||
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References
Keywords
