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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
3 Results for "
VHL Ligand8
" in MedChemExpress (MCE) Product Catalog:
Products (3)
3 Results for "VHL Ligand8" in MCE Product Catalog:
Target:
Research Areas:
VHL Ligand 8 is a VHL ligand. VHL Ligand 8 can be used to synthesize ARD-266 (HY-133020), a highly potent and VHL E3 ligase-based androgen receptor (AR) PROTAC degrader. ARD-266 effectively induces degradation of AR protein in AR-positive LNCaP, VCaP, and 22Rv1 prostate cancer cell lines with DC50 values of 0.2-1 nM .
Cat. No.: HY-163219
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VHL Ligand 8-PEG2-O-piperidine-Boc is a conjugate of E3 ubiquitin ligase ligand-Linker, which can be used to synthesize complete PROTACs molecules.
Cat. No.: HY-184670
CAS No.: 2313230-74-7
Target:
Research Areas:
VHL Ligand 8 is a von Hippel-Lindau (VHL) protein ligand. VHL Ligand 8 can be used in PROTAC synthesis-related research, such as for the synthesis of PROTAC BRD4 Degrader-3 (HY-135558) .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
