2. PROTAC
  3. Ligands for E3 Ligase
  4. VHL Ligand 41

VHL Ligand 8 is a von Hippel-Lindau (VHL) protein ligand. VHL Ligand 8 can be used in PROTAC synthesis-related research, such as for the synthesis of PROTAC BRD4 Degrader-3 (HY-135558).

For research use only. We do not sell to patients.

VHL Ligand 41

VHL Ligand 41 Chemical Structure

CAS No. : 2313230-74-7

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VHL Ligand 41 Related Antibodies

Top Publications Citing Use of Products

View All Ligands for E3 Ligase Isoform Specific Products:

View All Isoforms
von Hippel-Lindau (VHL) MDM2 Cereblon IAP KLHDC2 Fbxo3 RNF4 DCAF11 DCAF1 UHRF1 TRIM21 NEURL1B KLHL41 RNF114 DDB1 FEM1B

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Description

VHL Ligand 8 is a von Hippel-Lindau (VHL) protein ligand. VHL Ligand 8 can be used in PROTAC synthesis-related research, such as for the synthesis of PROTAC BRD4 Degrader-3 (HY-135558)[1].

IC50 & Target[1]

VHL

 

In Vitro

VHL Ligand 8 can be used to synthesize PROTAC BRD4 Degrader-3 (HY-135558), PROTAC BRD4 Degrader-3 (compound 1004.1) is an effective PROTAC linked by von Hippel-Lindau ligand and BRD4 ligand[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

VHL Ligand 41 Related Antibodies
Molecular Weight

432.54

Formula

C21H28N4O4S
CAS No.
SMILES

N[C@@H](C(C)(C)C)C(N(C[C@@H]1O)[C@@H](C1)C(NOC2=CC=C(C(SC=N3)=C3C)C=C2)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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VHL Ligand 41 Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

VHL Ligand 412313230-74-7VHL Ligand41VHL Ligand-41Ligands for E3 LigaseE3 ligase-recruiting MoietyInhibitorinhibitorinhibit

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