1 Result for "

Vinburnine (Standard)

" in MedChemExpress (MCE) Product Catalog:
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1 Results for "Vinburnine (Standard)" in MCE Product Catalog:

Vinburnine (Standard)
Vinburnine (Standard)
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Cat. No.: HY-B1180R
CAS No.: 4880-88-0
Synonyms: (-)-Eburnamonine (Standard); (-)-Vincamone (Standard)
Category:  

Apocynaceae Alkaloids Hunteria zeylanica Plants Indole Alkaloids

Target:  

Reference Standards Apoptosis p38 MAPK

Vinburnine ((-)-Eburnamonine; (-)-Vincamone) (Standard) is the analytical standard of Vinburnine (HY-B1180). This product is intended for research and analytical applications. Vinburnine ((-)-Eburnamonine; (-)-Vincamone) phosphate is an orally active, blood-brain barrier permeable immunomodulator and apoptosis inducer. Vinburnine drives the secretion of IL-24 by activating the P38/MAPK/ATF3 signaling axis. Vinburnine induces reactive oxygen species production and DNA damage in cancer cells, thereby inhibiting cancer cell proliferation, activating the apoptotic cascade, and enhancing CD8+ T cell function to remodel the tumor immune microenvironment. Vinburnine can be used in the research of diseases such as melanoma .
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