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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
28 Results for "
Wnt3a
" in MedChemExpress (MCE) Product Catalog:
Products (28)
28 Results for "Wnt3a" in MCE Product Catalog:
9
9 Publications Verification
Cat. No.: HY-P70453B
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Wnt3a Surrogate, Human (HEK293, Fc)
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3
3 Cited Publications
Cat. No.: HY-P70453C
Purity: ≥ 95%, as determined by Bis-Tris PAGE.
Synonyms: Wnt-3a; Wnt 3a; Wnt3a protein; Wnt3a
2
2 Cited Publications
Target:
Research Areas:
TFMB-(S)-2-HG is a potent TET2 inhibitor. TFMB-(S)-2-HG also inhibits the EglN prolyl hydroxylases. TFMB-(S)-2-HG downregulates Wnt3a, β-catenin (intranuclear) protein expression. TFMB-(S)-2-HG inhibits osteogenic differentiation of cells. TFMB-(S)-2-HG has the potential for the research of acute myeloid leukemia (AML) .
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1 Cited Publications
ABC99 is an N-hydroxyhydantoin (NHH) carbamate that selectively inhibits the Wnt-deacylating enzyme NOTUM (IC50=13 nM). ABC99 preserves Wnt3A signaling in the presence of NOTUM .
Cat. No.: HY-B0194
CAS No.: 51322-75-9
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Tizanidine, a skeletal muscle relaxant, is an orally effective central α2-adrenoceptor agonist (IC50 = 6.9 nmol). Tizanidine primarily exerts muscle relaxation effects by inhibiting the release of excitatory amino acids (glutamate and aspartate) from the presynaptic terminals of spinal cord interneurons. Tizanidine has anti-injury activity and can inhibit gastrointestinal (GI) transport. Tizanidine can inhibit the proliferation, migration, and invasion of lung cancer cells and induce cell apoptosis by upregulating Nischarin and inhibiting the AKT and Wnt3a/β-catenin signaling pathways. Tizanidine can be used to treat spasticity caused by diseases such as multiple sclerosis (MS), stroke, and spinal cord injury (SCI) [3] .
Cat. No.: HY-B0194A
CAS No.: 64461-82-1
Target:
Research Areas:
Tizanidine hydrochloride, a skeletal muscle relaxant, is an orally effective central α2-adrenoceptor agonist (IC50 = 6.9 nmol). Tizanidine hydrochloride primarily exerts muscle relaxation effects by inhibiting the release of excitatory amino acids (glutamate and aspartate) from the presynaptic terminals of spinal cord interneurons. Tizanidine hydrochloride has anti-injury activity and can inhibit gastrointestinal (GI) transport. Tizanidine hydrochloride can inhibit the proliferation, migration, and invasion of lung cancer cells and induce cell apoptosis by upregulating Nischarin and inhibiting the AKT and Wnt3a/β-catenin signaling pathways. Tizanidine hydrochloride can be used to treat spasticity caused by diseases such as multiple sclerosis (MS), stroke, and spinal cord injury (SCI) [3] .
Synonyms: RXC004
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Zamaporvint (RXC004) is an orally active and selective inhibitor of Wnt. Zamaporvint targete membrane-bound o-acyltransferase Porcupine and inhibited Wnt ligand palmitoylation, secretion, and pathway activation. Zamaporvint displays a favorable pharmacokinetic profile and shows potent antiproliferative effects in Wnt ligand-dependent colorectal and pancreatic cell lines. Zamaporvint possesses multiple antitumor mechanisms and can be used in cancer research .
Cat. No.: HY-P990841
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Research Areas:
Cat. No.: HY-160709
CAS No.: 1397006-01-7
Wnt/β-catenin-IN-2 (Compound 3235-0367) is a Wnt/β-catenin signaling pathway inhibitor, with IC50 and KD values of 7.1 and 2.5 μM, respectively. Wnt/β-catenin-IN-2 can be used for the research of cancer .
Cat. No.: HY-B0194S
CAS No.: 1188331-19-2
Cat. No.: HY-RS15835
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WNT3A Human Pre-designed siRNA Set A contains three designed siRNAs for WNT3A gene (Human), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P10204
CAS No.: 2416664-25-8
Cat. No.: HY-RS16706
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Research Areas:
Wnt3a Mouse Pre-designed siRNA Set A contains three designed siRNAs for Wnt3a gene (Mouse), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-RS23141
Target:
Research Areas:
Wnt3a Rat Pre-designed siRNA Set A contains three designed siRNAs for Wnt3a gene (Rat), as well as a negative control, a positive control, and a FAM-labeled negative control.
Cat. No.: HY-P70453D
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: Wnt3a Surrogate, Human (HEK293, N-hFc)
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
