2331255-53-7
2331255-53-7
Chemical Structure
ABC99
- CAS No.: 2331255-53-7
- Formula:C22H21ClN4O5
- Molecular Weight:456.88
IUPAC Name: 7-(4-chlorobenzyl)-1,3-dioxohexahydroimidazo[1,5-a]pyrazin-2(3H)-yl 2,3-dihydro-4H-benzo[b][1,4]oxazine-4-carboxylate
InChIKey: OZPZCETZTBBQBO-UHFFFAOYSA-N
SMILES: O=C(N1C2=CC=CC=C2OCC1)ON(C3=O)C(N4C3CN(CC5=CC=C(Cl)C=C5)CC4)=O
Biological Activity: ABC99 is an N-hydroxyhydantoin (NHH) carbamate that selectively inhibits the Wnt-deacylating enzyme NOTUM (IC50=13 nM). ABC99 preserves Wnt3A signaling in the presence of NOTUM[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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ABC99 | 98.48% | ABC99 is an N-hydroxyhydantoin (NHH) carbamate that selectively inhibits the Wnt-deacylating enzyme NOTUM (IC50=13 nM). ABC99 preserves Wnt3A signaling in the presence of NOTUM. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.60
HY-125143ABC34 -
Similarity Score 0.60
HY-116895JJH260 -
Similarity Score 0.60
HY-164838ABC47 -
Similarity Score 0.58
HY-120252ABC44 -
Similarity Score 0.55
HY-120126ML378 -
Similarity Score 0.48
HY-106995PD 172760 -
Similarity Score 0.47
HY-117474MJN110 -
Similarity Score 0.46
HY-101439JTT-552 -
Similarity Score 0.46
HY-1010612-MPMDQ -
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