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ABC44 is a potent serine hydrolase inhibitor with IC50s of 0.1 μM and 6.5 μM for palmitoyl protein thioesterase 1 (PPT1) in situ and in vitro, respectively. ABC44 can be used for researching infantile neuronal ceroid lipofuscinosis.

For research use only. We do not sell to patients.

ABC44 Chemical Structure

ABC44 Chemical Structure

CAS No. : 1831135-46-6

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Based on 1 publication(s) in Google Scholar

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Description

ABC44 is a potent serine hydrolase inhibitor with IC50s of 0.1 μM and 6.5 μM for palmitoyl protein thioesterase 1 (PPT1) in situ and in vitro, respectively. ABC44 can be used for researching infantile neuronal ceroid lipofuscinosis[1].

IC50 & Target

IC50: 0.1 μM (PPT1 in situ), 6.5 μM (PPT1 in vitro)[1]

Molecular Weight

576.69

Formula

C31H40N6O5

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(N1CCN(C2=CC=C(OC)C=C2)CC1)ON(C3=O)C(N4C3CN(CC5CCN(CC6=CC=CC=C6)CC5)CC4)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Purity & Documentation

Purity: ≥98.0%

References
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ABC44 Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
ABC44
Cat. No.:
HY-120252
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