1900754-56-4
Chemical Structure
Zamaporvint
Synonym(s): RXC004
- CAS No.: 1900754-56-4
- Formula:C21H16F3N7O
- Molecular Weight:439.39
InChIKey: QMLOYDPILBUVBV-UHFFFAOYSA-N
SMILES: O=C(CN1C=NC(C2=CC(C(F)(F)F)=NC=C2)=C1C)NC3=NC=C(C4=CN=CC=N4)C=C3
Biological Activity: Zamaporvint (RXC004) is an orally active and selective inhibitor of Wnt. Zamaporvint targete membrane-bound o-acyltransferase Porcupine and inhibited Wnt ligand palmitoylation, secretion, and pathway activation. Zamaporvint displays a favorable pharmacokinetic profile and shows potent antiproliferative effects in Wnt ligand-dependent colorectal and pancreatic cell lines. Zamaporvint possesses multiple antitumor mechanisms and can be used in cancer research[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Zamaporvint | 99.76% | Zamaporvint (RXC004) is an orally active and selective inhibitor of Wnt. Zamaporvint targete membrane-bound o-acyltransferase Porcupine and inhibited Wnt ligand palmitoylation, secretion, and pathway activation. Zamaporvint displays a favorable pharmacokinetic profile and shows potent antiproliferative effects in Wnt ligand-dependent colorectal and pancreatic cell lines. Zamaporvint possesses multiple antitumor mechanisms and can be used in cancer research. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
-
Similarity Score 0.79
HY-156551Porcn-IN-2 -
Similarity Score 0.63
HY-17545LGK974 -
Similarity Score 0.48
HY-100853IWP-O1 -
Similarity Score 0.48
HY-143576P2X3 antagonist 37 -
Similarity Score 0.47
HY-W1124914-(2,6-Di(pyrazin-2-yl)pyridin-4-yl)benzoic acid -
Similarity Score 0.47
HY-15493AN-019 -
Similarity Score 0.46
HY-16749ARPexidartinib hydrochloride (Standard) -
Similarity Score 0.46
HY-16749RPexidartinib (Standard) -
Similarity Score 0.46
HY-18814WB-BC-15 -
Explore the MedChemAI to find more analogs
