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Cat. No.: HY-18814

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WB-BC-15

Name: WB-BC-15
Brand: MedChemExpress
SKU: HY-18814
Availability: PreOrder

(Synonyms: WGB-BC-15)

WB-BC-15 (WGB-BC-15) is a c-Abl kinase inhibitor. WB-BC-15 can increase radiation-induced germ-cell apoptosis, with EC₅₀ of 10.5 μM.

For research use only. We do not sell to patients.

CAS No.: 309760-28-9
Formula: C₂₂H₁₈N₆O
Molecular Weight:382.42

Storage:

Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month

Data Sheet (274 KB)

WB-BC-15 Chemical Structure

CAS No.: 309760-28-9

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

WB-BC-15 (WGB-BC-15) is a c-Abl kinase inhibitor. WB-BC-15 can increase radiation-induced germ-cell apoptosis, with EC₅₀ of 10.5 μM^[1].

All Bcr-Abl Isoforms :

Abl
Bcr-Abl

Chemical Information

CAS No. 309760-28-9
Appearance Solid
Molecular Weight 382.42
Formula C₂₂H₁₈N₆O
Color Off-white to light yellow
SMILES

CC1=CC=C(NC(C2=CC=CN=C2)=O)C=C1NC3=NC=CC(C4=CC=CN=C4)=N3
Synonyms

WGB-BC-15
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (274 KB)
SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Deng X, et, al. Caenorhabditis elegans ABL-1 antagonizes p53-mediated germline apoptosis after ionizing irradiation. Nat Genet. 2004 Aug;36(8):906-12. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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WB-BC-15

All Bcr-Abl Isoforms