1. Membrane Transporter/Ion Channel
  2. P2X Receptor
  3. P2X3 antagonist 37

P2X3 antagonist 37 is a potent P2X3 receptor antagonist with an IC50 of 32.45 nM for hP2X3 (WO2021115225A1, example 68).

For research use only. We do not sell to patients.

P2X3 antagonist 37 Chemical Structure

P2X3 antagonist 37 Chemical Structure

CAS No. : 2649318-40-9

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Description

P2X3 antagonist 37 is a potent P2X3 receptor antagonist with an IC50 of 32.45 nM for hP2X3 (WO2021115225A1, example 68)[1].

Molecular Weight

431.30

Formula

C18H9F4N7O2

CAS No.
SMILES

O=C(NC1=NC=C(F)C=C1)CN2C3=CC(C#N)=NN3C4=NC(C(F)(F)F)=CC=C4C2=O

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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P2X3 antagonist 37 Related Classifications

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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P2X3 antagonist 37
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HY-143576
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