2649318-40-9
2649318-40-9
Chemical Structure
P2X3 antagonist 37
- CAS No.: 2649318-40-9
- Formula:C18H9F4N7O2
- Molecular Weight:431.30
IUPAC Name: 2-(2-cyano-5-oxo-8-(trifluoromethyl)pyrazolo[1,5-a]pyrido[3,2-e]pyrimidin-4(5H)-yl)-N-(5-fluoropyridin-2-yl)acetamide
InChIKey: UOBGZZXUXDYSDK-UHFFFAOYSA-N
SMILES: O=C(NC1=NC=C(F)C=C1)CN2C3=CC(C#N)=NN3C4=NC(C(F)(F)F)=CC=C4C2=O
Biological Activity: P2X3 antagonist 37 is a potent P2X3 receptor antagonist with an IC50 of 32.45 nM for hP2X3 (WO2021115225A1, example 68)[1].
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P2X3 antagonist 37 | P2X3 antagonist 37 is a potent P2X3 receptor antagonist with an IC50 of 32.45 nM for hP2X3 (WO2021115225A1, example 68). | |||||||||||||||||||||
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