1 Result for "

YM-359445

" in MedChemExpress (MCE) Product Catalog:
Products (1)

1 Results for "YM-359445" in MCE Product Catalog:

Cat. No.: HY-117039
CAS No.: 1020067-28-0
Target:  

VEGFR

Research Areas:  

Cancer

YM-359445 dihydroxybutanedioate is an orally active VEGFR2 tyrosine kinase inhibitor, with an IC50 of 8.5 nM. YM-359445 dihydroxybutanedioate shows a complete inhibition of vascular permeability induced by VEGF. YM-359445 dihydroxybutanedioate shows antitumor activity against both lung cancer and Paclitaxel (HY-B0015)-resistant colon cancer .
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