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Results for "

ammonia

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amino Acid Derivatives (1) Amino Acid Oxidase (1) Aminoacyl-tRNA Synthetase (1) Apical Sodium-Dependent Bile Acid Transporter (1) Apoptosis (1) Bacterial (6) Biochemical Assay Reagents (16) DNA/RNA Synthesis (3) Drug Derivative (1) Drug Intermediate (2) Drug Metabolite (1) Endogenous Metabolite (10) Environmental Pollutants (3) Fluorescent Dye (21) Glutaminase (2) Interleukin Related (1) Isotope-Labeled Compounds (1) NADH Dehydrogenase (1) NO Synthase (1) Protein Arginine Deiminase (1) Reactive Oxygen Species (ROS) (3) Reference Standards (4) Sigma Receptor (2) TGF-beta/Smad (1) TMV (1) Urease (1)
By Research Areas:	Cancer (9) Cardiovascular Disease (3) Endocrinology (1) Infection (4) Inflammation/Immunology (2) Metabolic Disease (20) Neurological Disease (4)

By Targets:

Amino Acid Derivatives (1)

Amino Acid Oxidase (1)

Aminoacyl-tRNA Synthetase (1)

Apical Sodium-Dependent Bile Acid Transporter (1)

Apoptosis (1)

Bacterial (6)

Biochemical Assay Reagents (16)

DNA/RNA Synthesis (3)

Drug Derivative (1)

Drug Intermediate (2)

Drug Metabolite (1)

Endogenous Metabolite (10)

Environmental Pollutants (3)

Fluorescent Dye (21)

Glutaminase (2)

Interleukin Related (1)

Isotope-Labeled Compounds (1)

NADH Dehydrogenase (1)

NO Synthase (1)

Protein Arginine Deiminase (1)

Reactive Oxygen Species (ROS) (3)

Reference Standards (4)

Sigma Receptor (2)

TGF-beta/Smad (1)

TMV (1)

Urease (1)

By Research Areas:

Cancer (9)

Cardiovascular Disease (3)

Endocrinology (1)

Infection (4)

Inflammation/Immunology (2)

Metabolic Disease (20)

Neurological Disease (4)

Inhibitors & Agonists

Screening Libraries

Fluorescent Dye

Biochemical Assay Reagents

Peptides

MCE Kits

Inhibitory Antibodies

Natural
Products

Recombinant Proteins

Isotope-Labeled Compounds

Antibodies

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B1692

L-Methionine-DL-sulfoximine 5+ Cited Publications MSX; MSO	Glutaminase	Neurological Disease
L-Methionine-DL-sulfoximine (MSX; MSO), a highly specific and irreversible inhibitor of Glutamine synthetase (GS), is also a potent convulsant which metabolically and morphologically primarily affects astroglia. L-Methionine-DL-sulfoximine has been employed to inhibit the Gln-dependent ammonia-stimulated neuronal toxicity in vitro, potentiating Gln deficit-dependent depression. L-Methionine-DL-sulfoximine tremendously increases the rate of release of fixed nitrogen in cyanobacteria. L-Methionine-DL-sulfoximine is a promising candidate for research in biofertilizers and convulsive seizures (CS) .

HY-B1142

Lipoamide Maximum Cited Publications 9 Publications Verification (±)-α-Lipoamide; DL-Lipoamide; DL-6,8-Thioctamide	NO Synthase	Others
Lipoamide ((±)-α-Lipoamide) is a monocarboxylic acid derivative of a neutral amide, formed by the condensation of the carboxyl group of lipoic acid and ammonia. Lipoamide protects against oxidative stress-mediated neuronal cell damage and also acts as a coenzyme to transfer acetyl groups and hydrogen during pyruvate deacylation. Lipoamide also stimulates mitochondrial biogenesis in adipocytes through the endothelial NO synthase-cGMP-protein kinase G signaling pathway .

HY-N10574

Queuine 1 Publications Verification	Bacterial	Metabolic Disease Cancer
Queuine is a selective substrate for tRNA guanine transglycosylase (TGT) and can be incorporated into eukaryotic tRNA. Queuine promotes tRNA modification, affecting mitochondrial function and Warburg metabolic phenotype. If Queuine is deficient, aerobic glycolysis can be enhanced, oxidative phosphorylation can be inhibited, and Warburg metabolism can be promoted, accompanied by increased ammonia and lactate production and increased lactate dehydrogenase activity. Queuine can be used for autoimmune diseases (such as experimental models of multiple sclerosis) and cancer metabolic regulation, and its deficiency is associated with low tRNA modification in tumor cells .

HY-B1571

Bromophenol blue	Environmental Pollutants Fluorescent Dye	Others
Bromophenol blue is an acid phthalein dye, and it is used as a tracking dye for electrophoresis. Bromophenol blue is also used as a pH indicator, with a transition range of pH 3 to 4.6. Bromophenol blue is used as a sensor for the determination of several compounds including ammonia, drugs, proteins and amino acids. The binding of Bromophenol blue to proteins is accompanied by the appearance of a strong absorbance at 610 nm .

HY-P2767

Urease, Jack bean 1 Publications Verification	Bacterial	Others
Urease, Jack bean is derived from jack bean and Catalyzes hydrolysis of urea to carbon dioxide and ammonia. Urease, Jack bean is useful in the determination of urea in body fluids.

HY-B0543

Allylthiourea Thiosinamine; N-Allylthiourea	Reactive Oxygen Species (ROS)	Cancer
Allylthiourea can selectively inhibit the oxidation of ammonia. Allylthiourea is commonly used to inhibit nitrification by targeting ammonia monooxygenase and chelating copper in the active site to suppress its activity. Allylthiourea also exhibits anticancer activity, showing cytotoxicity against the MCF-7 cell line with an IC₅₀ of 5.22 mM. Allylthiourea can be utilized in research related to micropollutant biodegradability and cancer studies .

HY-B2087

Glycerol phenylbutyrate 1 Publications Verification HPN-100	Sigma Receptor	Cardiovascular Disease
Glycerol phenylbutyrate is a sigma-2 (σ2) receptor ligand, with a pK_i of 8.02. Glycerol phenylbutyrate (GPB) is a new generation ammonia scavenger agent .

HY-A0282

L-Ornithine L-aspartate	Amino Acid Derivatives	Metabolic Disease Inflammation/Immunology
L-Ornithine L-aspartate is a stable salt of two natural nonessential L-amino acids with oral activity: ornithine and aspartic acid. L-Ornithine L-aspartate lowers blood ammonia concentration and to eliminate symptoms of hepatic encephalopathy associated with liver cirrhosis. L-Ornithine L-aspartate also improves mitochondrial functions .

HY-100956

Flurofamide	Bacterial Urease	Infection Metabolic Disease
Flurofamide is an effective bacterial urease inhibitor and antibacterial agent. Flurofamide inhibits urease and partially inhibits the chemotactic activity of Helicobacter pylori strain CPY3401. Flurofamide inhibits the growth of Ureaplasma urealyticum. Flurofamide reduces blood ammonia. Flurofamide can be used in the research of infectious urinary stones .

HY-Y0286

Ammonium carbonate, 99% Hartshorn salt, 99%	Environmental Pollutants Biochemical Assay Reagents	Others
Ammonium carbonate (Ammonium carbonate), 99% is a solid amino compound that functions as a buffer, pH regulator, pore-forming agent, and electrocatalytic oxidation substrate. Ammonium carbonate, 99% is a GRAS-grade direct food additive with no restricted daily intake specified by FAO/WHO, and it shows no acute skin toxicity, clinical signs of toxicity, or effects on body weight in rats. Ammonium carbonate, 99% undergoes electrocatalytic oxidation in alkaline solutions with a Pt/C catalyst (carbonate adsorption interferes with activity). Ammonium carbonate, 99% can serve as a fuel for low-temperature polymer fuel cells and anion exchange membrane fuel cells (with performance superior to pure ammonia), and can also form pores in the carrier-free Pt cathode catalyst layer after low-temperature decomposition, thereby enhancing catalyst activity under low-humidity conditions and the performance of proton exchange membrane fuel cells .

HY-E70003

Glutamate dehydrogenase	Biochemical Assay Reagents	Endocrinology
Glutamate dehydrogenase is an enzyme in both prokaryotes and eukaryotic mitochondria. Glutamate dehydrogenase can be used for the enzymatic determination of ammonia, alpha-ketoglutaric acid, L-glutamate and urease .

HY-W004494

2-Aminoindan-2-phosphonic acid 1 Publications Verification	Biochemical Assay Reagents	Others
2-Aminoindan-2-phosphonic acid is an inhibitor of phenylalanine ammonia-lyase (PAL). 2-Aminoindan-2-phosphonic acid reduces the biosynthesis and accumulation of total phenolic compounds in the suspension cell culture system of Cistanche .

HY-B1529A

Citric acid triammonium 5+ Cited Publications Triammonium citrate	Apoptosis Endogenous Metabolite Bacterial	Others Cancer
Citric acid triammonium (Triammonium citrate) is formed by Citric acid (HY-N1428) reacting with ammonia in a molar ratio of 1:3. Citric acid triammonium can be used as the carbon source to prepare carbon quantum dots (CDs). Citric acid triammonium with higher nitrogen components might promote the nitrogen-based functional groups in CDs, leading to a more efficient emission-color tunability .

HY-P2987

L-Amino acid oxidase	Endogenous Metabolite Amino Acid Oxidase	Metabolic Disease
L-Amino acid oxidase is a homodimeric proteins containing flavin adenine dinucleotide. L-Amino acid oxidase can catalyze the stereospecific oxidative deamination of L-amino acids to α-keto acids and ammonia .

HY-D2493

Cyanine7 carboxylic acid Cy7 COOH	Fluorescent Dye	Others
Cyanine7 carboxylic acid (Cy7 COOH) is a derivative of Cy7 (HY-D0825) dye. Cyanine7 carboxylic acid contains carboxyl groups, which can condense ammonia to form covalent bonds .

HY-D2166

AF 594 NHS ester	Fluorescent Dye	Others
AF 594 NHS ester is a derivative of the red fluorescent dye AF 594 with high fluorescence quantum yield and high photostability (Ex=594 nm, Em=615 nm). AF 594 NHS ester can form an ester bond by reacting the NHS group with ammonia, with maximum excitation wavelength of 594 nm .

HY-134230

L-2-Aminooxy-3-phenylpropanoic acid L-α-aminooxy-β-phenylpropionic acid; AOPP	Biochemical Assay Reagents	Metabolic Disease
L-2-Aminooxy-3-phenylpropanoic acid (L-α-aminooxy-β-phenylpropionic acid; AOPP) is an inhibitor of L-phenylalanine ammonia-lyase (PAL). L-2-Aminooxy-3-phenylpropanoic acid inhibits lignification without reducing the number of tracheary elements formed .

HY-N10574A

Queuine dihydrochloride 1 Publications Verification	Others	Metabolic Disease Cancer
Queuine dihydrochloride is a selective substrate for tRNA guanine transglycosylase (TGT) and can be incorporated into eukaryotic tRNA. Queuine dihydrochloride promotes tRNA modification, affecting mitochondrial function and Warburg metabolic phenotype. If Queuine dihydrochloride is deficient, aerobic glycolysis can be enhanced, oxidative phosphorylation can be inhibited, and Warburg metabolism can be promoted, accompanied by increased ammonia and lactate production and increased lactate dehydrogenase activity. Queuine dihydrochloride can be used for autoimmune diseases (such as experimental models of multiple sclerosis) and cancer metabolic regulation, and its deficiency is associated with low tRNA modification in tumor cells .

HY-W115789

Sodium silicate	Environmental Pollutants Reactive Oxygen Species (ROS)	Others
Sodium silicate is a water-soluble silicate. Sodium silicate is widely used as a binder, particularly in the production of detergents, soaps, and cleaners. Sodium silicate promotes the deposition of suberin polyphenols and lignin at wound sites of potato tubers, accelerates callus structure formation, enhances ROS production, and induces the synthesis of total phenols and flavonoids. Sodium silicate reduces the weight loss rate and disease index of wounded potato tubers during storage .

HY-P3188

Nitrilase	Biochemical Assay Reagents	Others
Nitrilase is able to hydrolyze nitriles into their corresponding carboxylic acids and ammonia. Nitrilase is a green biocatalyst for the production of high value-added products .

HY-W004078

4-Hydroxybenzylamine	Endogenous Metabolite	Metabolic Disease
4-Hydroxybenzylamine is a natural biogenic amine. 4-Hydroxybenzylamine can be produced through the breakdown metabolism of glucosinolates, with glutamine serving as the non-classical ammonia donor. 4-Hydroxybenzylamine can be utilized for the study of plant amine biosynthesis .

HY-W041895

DL-Glutamic acid	Endogenous Metabolite DNA/RNA Synthesis Bacterial	Infection
DL-Glutamic acid is a racemic amino acid mixture and an antibacterial agent. DL-Glutamic acid reduces RNA and DNA levels, with a more significant effect on RNA. DL-Glutamic acid inhibits cell division of Rhodospirillum rubrum .

HY-W017692

2-Aminoindan-2-phosphonic acid hydrochloride 1 Publications Verification	Biochemical Assay Reagents	Metabolic Disease
2-Aminoindan-2-phosphonic acid hydrochloride is a competitive *phenylalanine ammonia* lyase (PAL)** inhibitor that significantly decreases the levels of total phenolic compounds and PheGs in plant cultured cells .

HY-169004

CBT-295	TGF-beta/Smad Interleukin Related	Neurological Disease Inflammation/Immunology
CBT-295 is an orally active autotaxin (ATX) inhibitor. CBT-295 exhibits a significant reduction in inflammatory cytokines like TGF-β, TNF-α and IL-6 levels, also reduced bile duct proliferation marker CK-19 and lowered liver fibrosis. The reversal of liver fibrosis with CBT-295 led to a reduction in blood and brain ammonia levels. CBT-295 also reduced neuroinflammation induced by ammonia. CBT-295 is promising for research of liver cirrhosis and associated encephalopathy .

HY-E70410

NAD Synthetase NAD+ Synthetase; Nicotinamide adenine dinucleotide synthetase	Endogenous Metabolite	Neurological Disease Metabolic Disease Cancer
NAD synthetase is responsible for the final step in the synthesis of nicotinamide adenine dinucleotide (NAD). The K_m values for NAD, ATP, and ammonia of NAD synthetase from Escherichia coli are 200 μM, 11 μM, and 0.65 μM, respectively, while the K_m values for NAD, ATP, and ammonia of NAD synthetase from yeast are 170 μM, 190 μM, and 64 μM, respectively. NAD synthetase can be used for enzymatic assays to determine ATP, ammonia, urea, or creatinine, and is also suitable for enzymatic cycling methods. Additionally, NAD synthetase holds potential for research into metabolic diseases, cancer, aging, and neurodegenerative diseases .

HY-P2736

Amidase	Endogenous Metabolite	Metabolic Disease
Amidases, a member of nitrilase superfamily, catalyzes the hydrolysis of an amide, leading to the formation of carboxylic acid and ammonia. Amidases contain a conserved stretch of approximately 130 amino acids known as the AS sequence, and play a role in important metabolic processes .

HY-N1964A

Gibberellic acid, suitable for plant cell culture	Drug Derivative	Metabolic Disease
Gibberellic acid, suitable for plant cell culture (GA₃, suitable for plant cell culture) is a natural plant growth regulator with oral bioactivity. Gibberellic acid, suitable for plant cell culture governs multiple plant developmental events, including seed germination, cell elongation, floral organ formation, and rice spikelet fertility. Gibberellic acid, suitable for plant cell culture optimizes root morphology and secondary metabolite production in Echinacea purpurea hairy roots, and serves as a bioactive seed priming agent to improve chilling stress tolerance in chickpea. Gibberellic acid, suitable for plant cell culture mediates modulation of enzyme activity and secondary metabolism in plants and exerts tissue-specific regulatory effects on antioxidant systems and lipid peroxidation in rats. Gibberellic acid, suitable for plant cell culture can be used in studies of plant growth, metabolism, and abiotic stress responses .

HY-E70002

Deamino-NADPH	Biochemical Assay Reagents	Others
Deamino-NADPH is a 2'-phosphorylated coenzyme. Deamino-NADPH can be used in ammonia determination .

HY-D2487

Sulfo Cy5 bis COOH	Fluorescent Dye	Others
Sulfo Cy5 bis COOH is a derivative of Cy5 (HY-D0821) dye containing sulfonate ions. Sulfo Cy5 bis COOH contains carboxyl groups, which can condense ammonia to form covalent bonds.

HY-129982

SC-435	Apical Sodium-Dependent Bile Acid Transporter	Metabolic Disease
SC-435 is an orally effective apical sodium codependent bile acid transporter (ASBT) inhibitor. SC-435 effectively removes neurotoxic bile acids and ammonia from the blood by inhibiting intestinal ASBT, thereby alleviating liver and brain damage caused by liver failure. SC-435 can alter hepatic cholesterol metabolism and lower plasma low-density lipoprotein-cholesterol concentrations .

HY-P2951

*Phenylalanine ammonia-lyase*	Biochemical Assay Reagents	Metabolic Disease
Phenylalanine ammonia-lyase is a non-mammalian enzyme converting phenylalanine into trans-cinnamic acid and ammonia. Phenylalanine ammonia-lyase can be used in the research of phenylketonuria .

HY-107792

Benurestat	Bacterial	Infection
Benurestat is an orally active urease inhibitor. Benurestat can be used for infected ureolysis research .

HY-E70003A

Glutamate Dehydrogenase, Bovine Liver	NADH Dehydrogenase	Others
Glutamate Dehydrogenase, Bovine Liver (EC 1.4.1.4) catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate and ammonia.

HY-W134309

Nickel(II) carbonate hydroxide tetrahydrate	Biochemical Assay Reagents	Others
Nickel(II) carbonate (hydroxide tetrahydrate) is insoluble in water but soluble in ammonia water and dilute acids. Nickel(II) carbonate (hydroxide tetrahydrate) is a kind of biological materials or organic compounds that are widely used in life science research .

HY-W142169

N-Formyl-L-histidine Formyl-L-histidine	Aminoacyl-tRNA Synthetase	Others
N-Formyl-L-histidine shows binding affinity to histidyl-tRNA synthetase with a K_i value of 4.6 μM. N-Formyl-L-histidine shows a competitive inhibition against L-histidine ammonia-lyase, inhibits urocanic acid formation from L-histidine with a K_i value of 4.26 mM .

HY-P2965

L-Lysine α-oxidase	Endogenous Metabolite	Cancer
L-Lysine α-oxidase is a potent anticancer agent. L-Lysine α-oxidase also a L-amino acid oxidase, deaminates L-lysine with the yield of H2O2, ammonia, and α-keto-ε-aminocaproate. L-Lysine α-oxidase shows cytotoxicity and anticancer activity .

HY-135078

2,5-Deoxyfructosazine NSC 270912	DNA/RNA Synthesis	Others
2,5-Deoxyfructosazine is a pyrazine derivative that can be found in cured tobacco and is used as a flavoring agent in the food and tobacco industry. Pyrazines, including 2,5-deoxyfructosazine, can be produced either by pyrolytic decomposition of natural compounds or by the reaction of sugars with alcoholic ammonia. 2,5-Deoxyfructosazine is also formed by the breakdown of D-glucosamine at neutral pH. Like glucosamine, 2,5-deoxyfructosazine has DNA strand breakage activity and strongly inhibits IL-2 production by Jurkat cells stimulated with phytohemagglutinin (IC₅₀=~1.25 mM).

HY-N11886

5-NH2-Baicalein	Drug Metabolite	Others
5-NH2-Baicalein is an aminated metabolite of Baicalein (HY-N0196). 5-NH2-Baicalein can be used for research of ammonia and ammonia-associated chronic diseases .

HY-114929

THDP17	Glutaminase	Neurological Disease
THDP17 is an orally active glutaminase inhibitor. THDP17 decreases ammonia production through glutaminase inhibition .

HY-134230A

L-2-Aminooxy-3-phenylpropanoic acid hydrobromide L-α-aminooxy-β-phenylpropionic acid hydrobromide; AOPP hydrobromide	Others	Metabolic Disease
L-2-Aminooxy-3-phenylpropanoic acid hydrobromide is a potent inhibitor of L-phenylalanine ammonia-lyase .

HY-W276162

Parvoline 2-Ethyl-3,5-dimethylpyridine	Biochemical Assay Reagents	Others
Parvoline (2-Ethyl-3,5-dimethylpyridine) is an aromatic compound that can be prepared from propanal and ammonia using the method of Oude-Alink .

HY-B0543R

Allylthiourea (Standard) Thiosinamine (Standard); N-Allylthiourea (Standard)	Reference Standards Reactive Oxygen Species (ROS)	Cancer
Allylthiourea (Standard) is the analytical standard of Allylthiourea. This product is intended for research and analytical applications. Allylthiourea can selectively inhibit the oxidation of ammonia. Allylthiourea is commonly used to inhibit nitrification by targeting ammonia monooxygenase and chelating copper in the active site to suppress its activity. Allylthiourea also exhibits anticancer activity, showing cytotoxicity against the MCF-7 cell line with an IC50 of 5.22 mM. Allylthiourea can be utilized in research related to micropollutant biodegradability and cancer studies [4].

HY-D2105

TAMRA-PEG3-NHS	Fluorescent Dye	Others
TAMRA-PEG3-NHS is a dye derivative of TAMRA (HY-135640) containing 3 PEG units. TAMRA-PEG3-NHS contains NHS groups that react with ammonia to form ester bonds.

HY-D2106

TAMRA-PEG4-NHS	Fluorescent Dye	Others
TAMRA-PEG4-NHS is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG4-NHS contains NHS groups that react with ammonia to form ester bonds.

HY-D2107

TAMRA-PEG8-NHS	Fluorescent Dye	Others
TAMRA-PEG8-NHS is a dye derivative of TAMRA (HY-135640) containing 8 PEG units. TAMRA-PEG8-NHS contains NHS groups that react with ammonia to form ester bonds.

HY-D1596B

(E)-Cyanine 3.5 chloride (E)-Cy3.5 NHS ester chloride; (E)-Cy 3.5 chloride	Fluorescent Dye	Others
(E)-Cyanine 3.5 ((E)-Cy3.5 NHS ester) chloride is a cyanine dye functionalized with a N-hydroxysuccinimide (NHS) group. (E)-Cyanine 3.5 chloride contains NHS groups that react with ammonia to form ester bonds (Ex/Em = 586/612 nm).

HY-D2110

TAMRA-PEG8-COOH	Fluorescent Dye	Others
TAMRA-PEG8-COOH is a dye derivative of TAMRA (HY-135640) containing 8 PEG units. TAMRA-PEG8-COOH contains carboxyl groups, which can condense ammonia to form covalent bonds.

HY-D2109

TAMRA-PEG4-COOH	Fluorescent Dye	Others
TAMRA-PEG4-COOH is a dye derivative of TAMRA (HY-135640) containing 4 PEG units. TAMRA-PEG4-COOH contains carboxyl groups, which can condense ammonia to form covalent bonds.

HY-D2108

TAMRA-PEG3-COOH	Fluorescent Dye	Others
TAMRA-PEG3-COOH is a dye derivative of TAMRA (HY-135640) containing 3 PEG units. TAMRA-PEG3-COOH contains carboxyl groups, which can condense ammonia to form covalent bonds.

HY-B2087R

Glycerol phenylbutyrate (Standard) HPN-100 (Standard)	Reference Standards Sigma Receptor	Cardiovascular Disease
Glycerol phenylbutyrate (Standard) is the analytical standard of Glycerol phenylbutyrate. This product is intended for research and analytical applications. Glycerol phenylbutyrate is a sigma-2 (σ2) receptor ligand, with a pK_i of 8.02. Glycerol phenylbutyrate (GPB) is a new generation ammonia scavenger agent .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B1142

Lipoamide Maximum Cited Publications 9 Publications Verification (±)-α-Lipoamide; DL-Lipoamide; DL-6,8-Thioctamide	Natural Products Human Gut Microbiota Metabolites Microorganisms Classification of Application Fields Other Diseases Endogenous metabolite Disease Research Fields Source Classification	NO Synthase
Lipoamide ((±)-α-Lipoamide) is a monocarboxylic acid derivative of a neutral amide, formed by the condensation of the carboxyl group of lipoic acid and ammonia. Lipoamide protects against oxidative stress-mediated neuronal cell damage and also acts as a coenzyme to transfer acetyl groups and hydrogen during pyruvate deacylation. Lipoamide also stimulates mitochondrial biogenesis in adipocytes through the endothelial NO synthase-cGMP-protein kinase G signaling pathway .

HY-N10574

Queuine 1 Publications Verification	Alkaloids Microorganisms Pyrrole Alkaloids Source Classification	Bacterial
Queuine is a selective substrate for tRNA guanine transglycosylase (TGT) and can be incorporated into eukaryotic tRNA. Queuine promotes tRNA modification, affecting mitochondrial function and Warburg metabolic phenotype. If Queuine is deficient, aerobic glycolysis can be enhanced, oxidative phosphorylation can be inhibited, and Warburg metabolism can be promoted, accompanied by increased ammonia and lactate production and increased lactate dehydrogenase activity. Queuine can be used for autoimmune diseases (such as experimental models of multiple sclerosis) and cancer metabolic regulation, and its deficiency is associated with low tRNA modification in tumor cells .

HY-N10574A

Queuine dihydrochloride 1 Publications Verification	Alkaloids Microorganisms Pyrrole Alkaloids Source Classification	Others
Queuine dihydrochloride is a selective substrate for tRNA guanine transglycosylase (TGT) and can be incorporated into eukaryotic tRNA. Queuine dihydrochloride promotes tRNA modification, affecting mitochondrial function and Warburg metabolic phenotype. If Queuine dihydrochloride is deficient, aerobic glycolysis can be enhanced, oxidative phosphorylation can be inhibited, and Warburg metabolism can be promoted, accompanied by increased ammonia and lactate production and increased lactate dehydrogenase activity. Queuine dihydrochloride can be used for autoimmune diseases (such as experimental models of multiple sclerosis) and cancer metabolic regulation, and its deficiency is associated with low tRNA modification in tumor cells .

HY-W004078

4-Hydroxybenzylamine	Monophenols other families Classification of Application Fields Phenols Metabolic Disease Plants Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
4-Hydroxybenzylamine is a natural biogenic amine. 4-Hydroxybenzylamine can be produced through the breakdown metabolism of glucosinolates, with glutamine serving as the non-classical ammonia donor. 4-Hydroxybenzylamine can be utilized for the study of plant amine biosynthesis .

HY-W041895

DL-Glutamic acid	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Other Diseases Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite DNA/RNA Synthesis Bacterial
DL-Glutamic acid is a racemic amino acid mixture and an antibacterial agent. DL-Glutamic acid reduces RNA and DNA levels, with a more significant effect on RNA. DL-Glutamic acid inhibits cell division of Rhodospirillum rubrum .

HY-N11886

5-NH2-Baicalein	Flavonoids Classification of Application Fields Animals Flavones Other Diseases Endogenous metabolite Disease Research Fields Source Classification	Drug Metabolite
5-NH2-Baicalein is an aminated metabolite of Baicalein (HY-N0196). 5-NH2-Baicalein can be used for research of ammonia and ammonia-associated chronic diseases .

HY-D1596B

(E)-Cyanine 3.5 chloride (E)-Cy3.5 NHS ester chloride; (E)-Cy 3.5 chloride	Lipid	Fluorescent Dye
(E)-Cyanine 3.5 ((E)-Cy3.5 NHS ester) chloride is a cyanine dye functionalized with a N-hydroxysuccinimide (NHS) group. (E)-Cyanine 3.5 chloride contains NHS groups that react with ammonia to form ester bonds (Ex/Em = 586/612 nm).

HY-W004078R

4-Hydroxybenzylamine (Standard)	Structural Classification Monophenols other families Phenols Plants Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
4-Hydroxybenzylamine (Standard) is the analytical reference standard of 4-Hydroxybenzylamine (HY-W004078). This product is used for research and analytical applications. 4-Hydroxybenzylamine is a natural biogenic amine. 4-Hydroxybenzylamine can be produced through the breakdown metabolism of glucosinolates, with glutamine serving as the non-classical ammonia donor. 4-Hydroxybenzylamine can be used for studying the biosynthesis of plant amines.

HY-N1836

3-Acetonyl-3-hydroxyoxindole 3-Hydroxy-3-acetonyloxindole	Infection Alkaloids Acanthaceae Classification of Application Fields Plants Disease Research Fields Indole Alkaloids Jacobaea cannabifolia (Less.) E. Wiebe Source Classification	TMV
3-Acetonyl-3-hydroxyoxindole (AHO) is a potent systemic acquired resistance (SAR) inducer in plants. 3-Acetonyl-3-hydroxyoxindole induces resistance in tobacco plants against infection with tobacco mosaic virus (TMV) and the fungal pathogen Erysiphe cichoracearum. 3-Acetonyl-3-hydroxyoxindole increases the level of pathogenesis-related gene 1 (PR-1) expression, salicylic acid (SA) accumulation and phenylalanine ammonia-lyase activity .

HY-N17443

Lobscurinine	Lycopodiaceae Structural Classification Natural Products Dendrolycopodium obscurum (L.) A. Haines Plants Source Classification	Drug Intermediate
Lobscurinine is a fascaplysin-type alkaloid that reacts with ammonia water to form Obscurinine .

HY-N15975

12:0 N-Biotinyl fatty acid, NHS	Lipid	Biochemical Assay Reagents
12:0 N-Biotinyl fatty acid, NHS is a biotinylated lipid. 12:0 N-Biotinyl fatty acid, NHS contains NHS groups that react with ammonia to form ester bonds .

Cat. No.	Product Name	Chemical Structure

HY-W777675

2,5-Deoxyfructosazine-13C4

2,5-Deoxyfructosazine- ¹³C₄ (NSC 270912- ¹³C₄) is the ¹³C-labeled 2,5-Deoxyfructosazine (HY-135078). 2,5-Deoxyfructosazine is a pyrazine derivative that can be found in cured tobacco and is used as a flavoring agent in the food and tobacco industry. Pyrazines, including 2,5-deoxyfructosazine, can be produced either by pyrolytic decomposition of natural compounds or by the reaction of sugars with alcoholic ammonia. 2,5-Deoxyfructosazine is also formed by the breakdown of D-glucosamine at neutral pH. Like glucosamine, 2,5-deoxyfructosazine has DNA strand breakage activity and strongly inhibits IL-2 production by Jurkat cells stimulated with phytohemagglutinin (IC₅₀=~1.25 mM).

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