2-Aminoindan-2-phosphonic acid
Based on 1 publication(s) in Google Scholar
2-Aminoindan-2-phosphonic acid is an inhibitor of phenylalanine ammonia-lyase (PAL). 2-Aminoindan-2-phosphonic acid reduces the biosynthesis and accumulation of total phenolic compounds in the suspension cell culture system of Cistanche.
For research use only. We do not sell to patients.
- Purity: 99.55%
- CAS No.: 141120-17-4
- Formula: C9H12NO3P
- Molecular Weight:213.17
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) 2-Aminoindan-2-phosphonic acid
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Biological Activity
Phenylalanine aminolyase (PAL)[1]
2-Aminoindan-2-phosphonic acid (0-2.0 μM; 0-28 days) significantly inhibits PAL activity (reducing it to 35.1%-82.7% of that in untreated cells on days 4-28) and decreases the accumulation of total phenolic compounds, Echinacoside (HY-N0020), Verbascoside (HY-N0021), Cistanoside A (HY-N0023), Tubuloside A (HY-N2155) and Salidroside (HY-N0109); except for Salidroside, PAL activity shows a strong correlation with the accumulation of all tested compounds[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 141120-17-4
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Appearance Solid
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Molecular Weight 213.17
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Formula C9H12NO3P
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Color Light yellow to yellow
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SMILES
O=P(O)(C1(CC2=C(C1)C=CC=C2)N)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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Plants
Integrative Analysis of Metabolic Signature and Phytohormone Response in Potato Under Heat, Drought and Salt Stresses. [Abstract]2026 Mar 9;15(5):844. PMID: 41829874
Solvent & Solubility
0.1 M NaOH : 10 mg/mL (46.91 mM; ultrasonic and adjust pH to 10 with 0.1 M NaOH)
H2O : 5.83 mg/mL (27.35 mM; ultrasonic and warming and adjust pH to 1 with 1 M HCL and heat to 60°C)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (277 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O / 0.1 M NaOH | 1 mM | 4.6911 mL | 23.4555 mL | 46.9109 mL | 117.2773 mL |
| 5 mM | 0.9382 mL | 4.6911 mL | 9.3822 mL | 23.4555 mL | |
| 10 mM | 0.4691 mL | 2.3455 mL | 4.6911 mL | 11.7277 mL | |
| 15 mM | 0.3127 mL | 1.5637 mL | 3.1274 mL | 7.8185 mL | |
| 20 mM | 0.2346 mL | 1.1728 mL | 2.3455 mL | 5.8639 mL | |
| 25 mM | 0.1876 mL | 0.9382 mL | 1.8764 mL | 4.6911 mL | |
| 0.1 M NaOH | 30 mM | 0.1564 mL | 0.7818 mL | 1.5637 mL | 3.9092 mL |
| 40 mM | 0.1173 mL | 0.5864 mL | 1.1728 mL | 2.9319 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
2-Aminoindan-2-phosphonic acid Related Classifications
HY-W004494 Related Classifications
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