611168-24-2
611168-24-2
Chemical Structure
Glycerol phenylbutyrate
Synonym(s): HPN-100
- CAS No.: 611168-24-2
- Formula:C33H38O6
- Molecular Weight:530.65
IUPAC Name: propane-1,2,3-triyl tris(4-phenylbutanoate)
InChIKey: ZSDBFLMJVAGKOU-UHFFFAOYSA-N
SMILES: O=C(CCCC1=CC=CC=C1)OC(COC(CCCC2=CC=CC=C2)=O)COC(CCCC3=CC=CC=C3)=O
Biological Activity: Glycerol phenylbutyrate is a sigma-2 (σ2) receptor ligand, with a pKi of 8.02. Glycerol phenylbutyrate (GPB) is a new generation ammonia scavenger agent[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
Glycerol phenylbutyrate | 99.81% | Glycerol phenylbutyrate is a sigma-2 (σ2) receptor ligand, with a pKi of 8.02. Glycerol phenylbutyrate (GPB) is a new generation ammonia scavenger agent. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Glycerol phenylbutyrate (Standard) | ≥98% | Glycerol phenylbutyrate (Standard) is the analytical standard of Glycerol phenylbutyrate. This product is intended for research and analytical applications. Glycerol phenylbutyrate is a sigma-2 (σ2) receptor ligand, with a pKi of 8.02. Glycerol phenylbutyrate (GPB) is a new generation ammonia scavenger agent. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Rescifina A, et al. Development of a Sigma-2 Receptor affinity filter through a Monte Carlo based QSAR analysis. Eur J Pharm Sci. 2017 Aug 30;106:94-101. [Content Brief]
- [2]. Oishi K, et al. Glycerol phenylbutyrate for the chronic management of urea cycle disorders. Expert Rev Endocrinol Metab. 2014 Sep;9(5):427-434. [Content Brief]
