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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
80 Results for "
bicyclic
" in MedChemExpress (MCE) Product Catalog:
Products (80)
80 Results for "bicyclic" in MCE Product Catalog:
8
Category:
Infection Microorganisms Antibiotics Disease Research Anticancer Disease Research Fields Other Antibiotics
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4
4 Cited Publications
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GRK5-IN-2 (compound 707), a pyridine-based bicyclic compound, is a potent G-protein-coupled receptor kinase 5 (GRK5) inhibitor with an IC50 of 49.7 μM. GRK5-IN-2 regulates the expression and/or release of insulin and is useful for the metabolic disease research .
2
Category:
Other Monoterpenes other families Terpenoids Other Diseases Plants Disease Research Fields
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1
1 Cited Publications
Cat. No.: HY-P1206
CAS No.: 174688-78-9
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DBU (1,8-diazabicyclo[5.4.0]undec-7-ene) is a bicyclic sterically hindered amidine with strong basicity, which possesses multiple properties such as nucleophilicity and coordination ability. DBU is prone to hydrolysis and can undergo addition, substitution, cyclization and other reactions with various substrates to form derivatives containing its scaffold. DBU can also be used as a catalyst .
Cat. No.: HY-P10033
CAS No.: 245080-24-4
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Category:
Santalum album Linn. Terpenoids Sesquiterpenes Other Diseases Plants Disease Research Fields Santalaceae
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AS1810722 is an orally active and potent STAT6 inhibitor with an IC50 of 1.9 nM. AS1810722 shows a good profile of CYP3A4 inhibition. AS1810722, a derivative of fused bicyclic pyrimidine, has the potential for allergic diseases such as asthma and atopic diseases research .
Cat. No.: HY-P2031
CAS No.: 26645-35-2
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Category:
Other Monoterpenes Terpenoids Other Diseases Plants Umbelliferae Vernonia Schreb. Disease Research Fields
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Cat. No.: HY-W010922
CAS No.: 162558-25-0
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Cat. No.: HY-W010649
CAS No.: 288-14-2
Target:
HSP Epigenetic Reader Domain ATP-binding cassette (ABC) transporters Bacterial Fungal Antibiotic
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Isoxazole is a member of the five-membered heterocycle drug scaffold. Isoxazole has been used as a BET bromodomain inhibitor and can improve β-cell function in a diabetic mouse model. Isoxazole and its derivatives exhibit broad biological activities (such as antimicrobial, antibacterial, antifungal, antiviral, anticancer, anti-inflammatory, immunomodulatory, analgesic, anti-tuberculosis, and anti-diabetic effects). For example, the bicyclic Isoxazole can act as an HSP90 inhibitor, and the tricyclic Isoxazole is promising as a selective multidrug resistance protein (MRP1) inhibitor .
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RNA splicing modulator 3 is an RNA splicing modulator. RNA splicing modulator 3 modulates nucleic acid splicing, including pre-mRNA splicing .
Cat. No.: HY-P6292
CAS No.: 2724212-01-3
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Cat. No.: HY-W570888
CAS No.: 206055-69-8
Synonyms: LNA-C(Bz)
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2'-O,4'-C-Methylenecytidine (LNA-C(Bz)) is a bicyclic nucleoside analogue with fixed N-type conformation. 2'-O,4'-C-Methylenecytidine can be used to synthesize oligonucleotides. 2'-O,4'-C-Methylenecytidine forms duplexes with complementary DNA and RNA strands .
Cat. No.: HY-W068697
CAS No.: 625-38-7
Synonyms: Vinylacetic acid
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3-Butenoic acid (Vinylacetic acid) can be used to synthesize bicyclic 3,6-dihydro-1,2-oxazine. Strained bicyclic 3,6-dihydro-1,2-oxazine is a reactive substrate in domino metathesis with an external alkene .
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
