489-84-9
489-84-9
Chemical Structure
Guaiazulene
- CAS No.: 489-84-9
- Formula:C15H18
- Molecular Weight:198.30
IUPAC Name: 7-isopropyl-1,4-dimethylazulene
InChIKey: FWKQNCXZGNBPFD-UHFFFAOYSA-N
SMILES: CC(C1=CC2=C(C)C=CC2=C(C)C=C1)C
Biological Activity: Guaiazulene is a bicyclic sesquiterpene. Guaiazulene exhibits various biological activities such as anti-inflammatory, antioxidant, hepatoprotective, antibacterial, and anti-tumor properties. Guaiazulene is also commonly used as a colorant in cosmetics. Guaiazulene shows in vitro cytotoxicity to rat neuronal cells and N2a neuroblastoma cells at high concentrations[1][2][3][4].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Guaiazulene | 99.08% | Guaiazulene is a bicyclic sesquiterpene. Guaiazulene exhibits various biological activities such as anti-inflammatory, antioxidant, hepatoprotective, antibacterial, and anti-tumor properties. Guaiazulene is also commonly used as a colorant in cosmetics. Guaiazulene shows in vitro cytotoxicity to rat neuronal cells and N2a neuroblastoma cells at high concentrations. | ||||||||||||||||||||
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Guaiazulene (Standard) | 99.84% | Guaiazulene (Standard) is the analytical standard of Guaiazulene (HY-N6951). This product is intended for research and analytical applications. Guaiazulene is a bicyclic sesquiterpene that can cross the blood-brain barrier. Guaiazulene exhibits various biological activities such as anti-inflammatory, antioxidant, hepatoprotective, antibacterial, and anti-tumor properties. Guaiazulene is also commonly used as a colorant in cosmetics. Guaiazulene shows in vitro cytotoxicity to rat neuronal cells and N2a neuroblastoma cells at high concentrations. | ||||||||||||||||||||
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References
- [1]. Togar B, et al. Guaiazulene biochemical activity and cytotoxic and genotoxic effects on rat neuron and N2a neuroblastom cells. J Intercult Ethnopharmacol. 2015 Jan-Mar;4(1):29-33. [Content Brief]
- [2]. Kourounakis AP, et al. Antioxidant activity of guaiazulene and protection against paracetamol hepatotoxicity in rats. J Pharm Pharmacol. 1997 Sep;49(9):938-42. [Content Brief]
- [3]. Ye Q, et al. Guaiazulene Triggers ROS-Induced Apoptosis and Protective Autophagy in Non-small Cell Lung Cancer. Front Pharmacol. 2021 Apr 15;12:621181. [Content Brief]
- [4]. Akram W, et al. Guaiazulene and related compounds: A review of current perspective on biomedical applications. Life Sci. 2023 Mar 1;316:121389. [Content Brief]
