1. Metabolic Enzyme/Protease
  2. Endogenous Metabolite
  3. Guaiazulene

Guaiazulene 

Cat. No.: HY-N6951 Purity: >98.0%
Handling Instructions

Guaiazulene is present in several essential oils of medicinal and aromatic plants, with antioxidant activity. Guaiazulene has in vitro cytotoxic activity against neuron and N2a neuroblastom (N2a-NB) cells.

For research use only. We do not sell to patients.

Guaiazulene Chemical Structure

Guaiazulene Chemical Structure

CAS No. : 489-84-9

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Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Description

Guaiazulene is present in several essential oils of medicinal and aromatic plants, with antioxidant activity. Guaiazulene has in vitro cytotoxic activity against neuron and N2a neuroblastom (N2a-NB) cells[1][2].

IC50 & Target

Human Endogenous Metabolite

 

Molecular Weight

198.30

Formula

C₁₅H₁₈

CAS No.

489-84-9

SMILES

CC(C1=CC2=C(C)C=CC2=C(C)C=C1)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 250 mg/mL (1260.72 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.0429 mL 25.2143 mL 50.4286 mL
5 mM 1.0086 mL 5.0429 mL 10.0857 mL
10 mM 0.5043 mL 2.5214 mL 5.0429 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 6.25 mg/mL (31.52 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 6.25 mg/mL (31.52 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

GuaiazuleneEndogenous MetaboliteInhibitorinhibitorinhibit

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Product Name:
Guaiazulene
Cat. No.:
HY-N6951
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