909561-15-5
Chemical Structure
AS1810722
- No. CAS: 909561-15-5
- Formula:C25H25F2N7O
- Molecular Weight:477.51
IUPAC Name: 2-(4-(4-((7-(3,5-difluorobenzyl)-7H-pyrrolo[2,3-d]pyrimidin-2-yl)amino)phenyl)piperazin-1-yl)acetamide
InChIKey: IJFRMEXSGYTWGY-UHFFFAOYSA-N
SMILES: O=C(N)CN1CCN(C2=CC=C(NC3=NC=C4C(N(CC5=CC(F)=CC(F)=C5)C=C4)=N3)C=C2)CC1
Biological Activity: AS1810722 is an orally active and potent STAT6 inhibitor with an IC50 of 1.9 nM. AS1810722 shows a good profile of CYP3A4 inhibition. AS1810722, a derivative of fused bicyclic pyrimidine, has the potential for allergic diseases such as asthma and atopic diseases research[1].
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AS1810722 | 98.10% | AS1810722 is an orally active and potent STAT6 inhibitor with an IC50 of 1.9 nM. AS1810722 shows a good profile of CYP3A4 inhibition. AS1810722, a derivative of fused bicyclic pyrimidine, has the potential for allergic diseases such as asthma and atopic diseases research. | ||||||||||||||||||||
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Keywords
