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Results for "

cassia

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Akt (4) Apoptosis (5) Bacterial (5) Bcl-2 Family (1) Biochemical Assay Reagents (1) Calcium Channel (1) Caspase (2) COX (3) DNA Alkylator/Crosslinker (1) DNA/RNA Synthesis (3) Drug Derivative (3) Drug Intermediate (2) Endogenous Metabolite (1) Estrogen Receptor/ERR (1) Fungal (1) GLUT (4) Glycosidase (3) HCV (4) HIV (2) Isotope-Labeled Compounds (1) Keap1-Nrf2 (1) MDM-2/p53 (1) Mitochondrial Metabolism (2) MMP (1) Monoamine Oxidase (3) NF-κB (4) PAK (1) Parasite (2) PDGFR (1) Phosphatase (1) Reactive Oxygen Species (ROS) (1) Reference Standards (12) STAT (1) TNF Receptor (2) Topoisomerase (2) Tyrosinase (2) Wnt (1) Xanthine Oxidase (2) β-catenin (1)
By Research Areas:	Cancer (12) Cardiovascular Disease (3) Endocrinology (2) Infection (16) Inflammation/Immunology (16) Metabolic Disease (7) Neurological Disease (9)

By Targets:

Akt (4)

Apoptosis (5)

Bacterial (5)

Bcl-2 Family (1)

Biochemical Assay Reagents (1)

Calcium Channel (1)

Caspase (2)

COX (3)

DNA Alkylator/Crosslinker (1)

DNA/RNA Synthesis (3)

Drug Derivative (3)

Drug Intermediate (2)

Endogenous Metabolite (1)

Estrogen Receptor/ERR (1)

Fungal (1)

GLUT (4)

Glycosidase (3)

HCV (4)

HIV (2)

Isotope-Labeled Compounds (1)

Keap1-Nrf2 (1)

MDM-2/p53 (1)

Mitochondrial Metabolism (2)

MMP (1)

Monoamine Oxidase (3)

NF-κB (4)

PAK (1)

Parasite (2)

PDGFR (1)

Phosphatase (1)

Reactive Oxygen Species (ROS) (1)

Reference Standards (12)

STAT (1)

TNF Receptor (2)

Topoisomerase (2)

Tyrosinase (2)

Wnt (1)

Xanthine Oxidase (2)

β-catenin (1)

By Research Areas:

Cancer (12)

Cardiovascular Disease (3)

Endocrinology (2)

Infection (16)

Inflammation/Immunology (16)

Metabolic Disease (7)

Neurological Disease (9)

Inhibitors & Agonists

Biochemical Assay Reagents

Natural
Products

Isotope-Labeled Compounds

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N0365

Sennoside A Maximum Cited Publications 6 Publications Verification	DNA/RNA Synthesis HIV	Infection
Sennoside A is an anthraquinone glycoside found in senna (Cassia angustifolia). Sennoside A is an HIV-1 inhibitor (IC₅₀=3.8 μM) that inhibits HIV-1 replication. Sennoside A also inhibits HIV-1 reverse transcriptase (RT)-related DNA polymerase (RDDP) and ribonuclease H (Ribonuclease H) with IC₅₀s of 1.9 μM and 5.3 μM, respectively .

HY-Y1426

2'-Hydroxyacetophenone o-Hydroxyacetophenone; o-Acetylphenol	Drug Intermediate	Others
2'-Hydroxyacetophenone is found in alcoholic beverages. 2'-Hydroxyacetophenone is present in tomato, cassia, fried beef, rum, whiskey, cocoa, coffee and black tea. 2'-Hydroxyacetophenone is a flavouring ingredient. Building block in chemical synthesis.

HY-N0261

Aurantio-obtusin 1 Publications Verification	TNF Receptor COX	Cardiovascular Disease Inflammation/Immunology
Aurantio-obtusin is a anthraquinone compound that can be extracted from cassia seed. Aurantio-obtusin has the effects of decreasing blood pressure, decreasing blood lipids and anti-inflammatory.Aurantio-obtusin is an orally active vasodilator. Aurantio-obtusin ameliorates hepatic steatosis through AMPK/ autophagy- and AMPK/TFEB mediated inhibition of lipid accumulation .

HY-N2098

Obtusifolin 4 Publications Verification	NF-κB	Cancer
Obtusifolin, isolated from the seeds of Cassia obtusifolia, regulates the gene expression and production of MUC5AC mucin in airway epithelial cells via inhibiting NF-kB pathway . Obtusifolin suppresses phthalate esters-induced breast cancer bone metastasis by targeting parathyroid hormone-related protein .

HY-W046353

2-Methoxycinnamaldehyde o-Methoxycinnamaldehyde	Apoptosis NF-κB Topoisomerase Mitochondrial Metabolism Caspase	Cancer
2-Methoxycinnamaldehyde (o-Methoxycinnamaldehyde) is a natural compound that can be isolated from Cinnamomum cassia. 2-Methoxycinnamaldehyde inhibits topoisomerase-I/II and NF-κB signaling pathway, causes mitochondrial dysfunction, induces lysosomal vesiculation, thereby leading to DNA damage and cell apoptosis. 2-Methoxycinnamaldehyde exhibits antitumor effects .

HY-N6057

Obtusin	Monoamine Oxidase	Neurological Disease
Obtusin, isolated from Cassia obtusifolia Linn seed, is a highly selective and competitive human monoamine oxidase-A (hMAO-A) inhibitor with an IC₅₀ of 11.12 μM and a K_i of 6.15 μM. Obtusin plays a preventive role in neurodegenerative diseases, especially anxiety and depression .

HY-N1973

Sennoside D	Others	Infection Inflammation/Immunology
Sennoside D is an anthraquinone glycoside, found in leaves and pods of Senna (Cassia angustifolia) .

HY-N4177

Rubrofusarin gentiobioside	Others	Metabolic Disease
Rubrofusarin gentiobioside is isolated from the seeds of Cassia tora L. Rubrofusarin gentiobioside has a radical scavenging effect .

HY-N3149A

2-Hydroxycinnamaldehyde	Wnt β-catenin STAT Apoptosis	Inflammation/Immunology
2-Hydroxycinnamaldehyde is a phenylpropanoid that can be isolated from the bark of Cinnamomum cassia. 2-Hydroxycinnamaldehyde inhibits Wnt/β-catenin, STAT3 signaling. 2-Hydroxycinnamaldehyde induces cell apoptosis 2-Hydroxycinnamaldehyde has antitumor and anti-inflammation activities .

HY-N6935

Sennidin B	DNA/RNA Synthesis HCV Akt GLUT	Infection Metabolic Disease
Sennidin B, a stereoisomer isolated from the leaves of Cassia angustifolia, has lower activity than Sennidin A. Sennidin A inhibits HCV NS3 helicase, with an IC₅₀ of 0.8 μM. Sennidin A induces phosphorylation of Akt and glucose transporter 4 (GLUT4) translocation. Sennidin A stimulates the glucose incorporation .

HY-N12281

Sennoside	Apoptosis MDM-2/p53 PAK Calcium Channel	Endocrinology Cancer
Sennoside is an orally active apoptosis inducer and stimulant laxative, found in Senna (Cassia angustifolia). Sennoside induces overexpression of wild-type p53 and p21/WAF as part of pathways mediating colonic epithelial cell apoptosis. Sennoside stimulates colonic peristalsis, reverses net water, sodium, chloride absorption to secretion and enhances potassium and calcium secretion. Sennoside increases paracellular permeability to small molecules, accelerates colon transit and softens fecal pellets. Sennoside can be used for the research of constipation, melanosis coli, and colorectal cancer .

HY-N7628

Cassiaside C Toralactone 9-O-β-D-gentiobioside	Endogenous Metabolite	Metabolic Disease
Cassiaside C (Toralactone 9-O-β-D-gentiobioside) is a naphthopyrone isolated from the seed of Cassia tora and has inhibitory activity on advanced glycation end products (AGE) formation in vitro .

HY-N11063

Obtusifolin-2-O-glucoside	Tyrosinase	Cancer
Obtusifolin-2-O-glucoside (compound 7) is a Tyrosinase inhibitor (IC₅₀=9.2 μM). Obtusifolin-2-O-glucoside can be isolated from cassia seed .

HY-N0365R

Sennoside A (Standard) Maximum Cited Publications 6 Publications Verification	Reference Standards HIV	Infection
Sennoside A (Standard) is the analytical standard of Sennoside A. This product is intended for research and analytical applications. Sennoside A is an anthraquinone glycoside, found in Senna (Cassia angustifolia) . Sennoside A is a HIV-1 inhibitor effective on HIV-1 replication .

HY-N7617

Toralactone 1 Publications Verification	Keap1-Nrf2	Cancer
Toralactone, isolated from Cassia obtusifolia, mediates hepatoprotection via an Nrf2-dependent anti-oxidative mechanism .

HY-130307

Rubrofusarin	Bacterial	Neurological Disease Inflammation/Immunology Cancer
Rubrofusarin is an orange polyketide pigment from Fusarium graminearum . Rubrofusarin is also an active ingredient of the Cassia species and ameliorates chronic restraint stress (CRS) -induced depressive symptoms through PI3K/Akt signaling. Rubrofusarin has anticancer, antibacterial, and antioxidant effects .

HY-N8581

5,5'-Dimethoxysecoisolariciresinol (-)-8,8'-Bisdihydrosiringenin	Others	Others
5,5'-Dimethoxysecoisolariciresinol ((-)-8,8'-Bisdihydrosiringenin) is a lignin. 5,5'-Dimethoxysecoisolariciresinol can be isolated from twigs of Cinnamomum cassia .

HY-N7604

Isorubrofusarin-6-O-β-gentiobioside Isorubrofusarin gentiobioside	Others	Others
Isorubrofusarin-6-O-β-gentiobioside (Isorubrofusarin gentiobioside) is a naphthopyrone glycoside isolated from Cassia obtusifolia Linn seeds .

HY-N0366R

Sennoside B (Standard)	Reference Standards PDGFR	Cancer
Sennoside B (Standard) is the analytical standard of Sennoside B. This product is intended for research and analytical applications. Sennoside B is an anthraquinone glycoside, found in large quantities in leaves and pods of Senna (Cassia angustifolia) . Sennoside B can inhibit PDGF-stimulated cell proliferation by binding to PDGF-BB and its receptor and by down-regulating the PDGFR-beta signaling pathway .

HY-W015069

4-Nitrocinnamic acid	Xanthine Oxidase	Others
4-Nitrocinnamic acid is a Phenylpropanoids product that can be isolated from the heartwoods of Cassia garrettiana .

HY-W019715

trans-4-(Trifluoromethyl)cinnamic acid	Drug Derivative	Others
trans-4-(Trifluoromethyl)cinnamic acid is a Phenylpropanoids product that can be isolated from the barks of Cinnamomum cassia Presl .

HY-N4179

Aurantio-obtusin β-D-glucoside Glucoaurantio-obtusin	Others	Metabolic Disease
Aurantio-obtusin β-D-glucoside (Glucoaurantio-obtusin), isolated from Cassiae Semen (seeds of Cassia tora), is a glucoside of aurantio-obtusin .

HY-N7603

Rubrofusarin triglucoside	Monoamine Oxidase	Neurological Disease
Rubrofusarin triglucoside is a glycoside compound isolated from Cassia obtusifolia Linn seeds. Rubrofusarin triglucoside inhibits human monoamine oxidase A (hMAO-A) with an IC₅₀ of 85.5 μM .

HY-N6936

Sennidin A	DNA/RNA Synthesis HCV Akt GLUT	Infection
Sennidin A, isolated from the leaves of Cassia angustifolia, inhibits HCV NS3 helicase, with an IC₅₀ of 0.8 μM. Sennidin A induces phosphorylation of Akt and glucose transporter 4 (GLUT4) translocation. Sennidin A stimulates the glucose incorporation .

HY-W046353A

(E)-2-Methoxycinnamaldehyde (E)-o-Methoxycinnamaldehyde	Tyrosinase	Neurological Disease
(E)-2-Methoxycinnamaldehyde ((E)-o-Methoxycinnamaldehyde) is a tyrosinase inhibitor with an IC₅₀ of 0.42 mM for mushroom tyrosinase. (E)-2-Methoxycinnamaldehyde is found in the twigs of Cinnamomum cassia. (E)-2-Methoxycinnamaldehyde can be used for the research of Parkinson's disease .

HY-Y1426R

2'-Hydroxyacetophenone (Standard) o-Hydroxyacetophenone (Standard); o-Acetylphenol (Standard)	Reference Standards Others	Others
2'-Hydroxyacetophenone (Standard) is the analytical standard of 2'-Hydroxyacetophenone. This product is intended for research and analytical applications. 2'-Hydroxyacetophenone is found in alcoholic beverages. 2'-Hydroxyacetophenone is present in tomato, cassia, fried beef, rum, whiskey, cocoa, coffee and black tea. 2'-Hydroxyacetophenone is a flavouring ingredient. Building block in chemical synthesis.

HY-167825

Barakol	MMP Apoptosis Bcl-2 Family Reactive Oxygen Species (ROS)	Neurological Disease Inflammation/Immunology Cancer
Barakol is a major compound found in Cassia siamea. Barakol inhibits MMP-3 activity. Barakol potentiates the anti-metastatic effect of Doxorubicin (HY-15142). Barakol induces apoptosis, with ROS generation, increase in expression ratio of Bax/Bcl-2, and caspase-9 activation. Barakol has laxative, anxiolytic, CNS depressant, and antioxidant, anticancer effects .

HY-N0261R

Aurantio-obtusin (Standard)	Reference Standards TNF Receptor COX	Cardiovascular Disease Inflammation/Immunology
Aurantio-obtusin (Standard) is the analytical standard of Aurantio-obtusin. This product is intended for research and analytical applications. Aurantio-obtusin is a anthraquinone compound that can be extracted from cassia seed. Aurantio-obtusin has the effects of decreasing blood pressure, decreasing blood lipids and anti-inflammatory.Aurantio-obtusin is an orally active vasodilator. Aurantio-obtusin ameliorates hepatic steatosis through AMPK/ autophagy-and AMPK/TFEB mediated inhibition of lipid accumulation .

HY-N16529

1,6,8-Trihydroxy-2,7-dimethoxy-3-methylanthraquinone	Glycosidase	Metabolic Disease
1,6,8-Trihydroxy-2,7-dimethoxy-3-methylanthraquinone (Compound 2) is a anthraquinone aglycone found in Cassia obtusefolia. 1,6,8-Trihydroxy-2,7-dimethoxy-3-methylanthraquinone can inhibit α-glucosidase with an IC₅₀ of 120.65 μg/mL. 1,6,8-Trihydroxy-2,7-dimethoxy-3-methylanthraquinone can be used for the research of diabetes .

HY-N12998

Torachrysone tetraglucoside	Others	Others
Torachrysone tetraglucoside is a phenolic glycoside , and can be isolated from the leguminous plant cassia .

HY-N15520

Moracin J	Others	Others
Moracin J is found in the leaves of Cassia fistula. Moracin J is a derivative of the benzofuran compound Moracin .

HY-N10939

Gluco-obtusin	Others	Infection Neurological Disease Inflammation/Immunology
Gluco-obtusin is an anthraquinone. Gluco-obtusin can be isolated from the seeds of Cassia obtusifolia .

HY-N15693

2-O-B-D-Glucopyranosyloxy-1,7,8-trimethoxy- 3-methylanthraquinone	Biochemical Assay Reagents	Infection Inflammation/Immunology
2-O-B-D-Glucopyranosyloxy-1,7,8-trimethoxy-3-methylanthraquinone can be found in the seeds of Cassia obtusifolia .

HY-N10369

1,2,3,7-Tetrahydroxy-8-methoxy-6-methyl-9,10-anthraquinone	Others	Others
1,2,3,7-Tetrahydroxy-8-methoxy-6-methyl-9,10-anthraquinone is an anthraquinone compound isolated from the seeds of Cassia obtusifolia .

HY-N16482

Cassiatannin A	COX	Inflammation/Immunology
Cassiatannin A is a tetramer of proanthocyanidin (HY-N0794) found in Cinnamomum cassia. Cassiatannin A shows COX-2 inhibitor activity with inhibition rate of 38, 52 and 97% at 10, 100 and 1000 μg/mL. Cassiatannin A can be used for the research of inflammation .

HY-N12006

6,8-Dihydroxy-1,2,7-trimethoxy-3-methylanthraquinone	Glycosidase	Others
6,8-Dihydroxy-1,2,7-trimethoxy-3-methylanthraquinone (compound 1) is an anthraquinone α-glucosidase inhibitor (IC₅₀:185 μM), which can be isolated from Cassia seeds .

HY-N7599

Chrysophanol triglucoside	Phosphatase Glycosidase	Metabolic Disease
Chrysophanol triglucoside is an anthraquinone isolated from Cassia obtusifolia, inhibits protein tyrosine phosphatases 1B (PTP1B) and α-glucosidase with IC₅₀s of 80.17 and 197.06 µM, respectively. Chrysophanol triglucoside has the potential for diabetes research .

HY-159104

Cinnamon bark oil, from Cinnamonum zeylanicum Blume Cinnamomum cassia oil	Fungal	Infection
Cinnamon bark oil, from Cinnamonum zeylanicum Blume is a antifungal agent against fungi causing respiratory tract mycoses .

HY-N3546

Cassiachromone	Parasite	Others
Cassiachromone can be isoalted from Cassia siamea .

HY-N1142

Torachrysone Nakahalene; Trachrysone; Torachryson	Others	Others
Torachrysone (Nakahalene; Trachrysone), a naphthalene, can be isolated from Cassia tora L .

HY-N4091

Tinnevellin glucoside	Others	Others
Tinnevellin glucoside, a naphthalene glycoside, isolated from Cassia senna leaves and pods .

HY-N3886

Evofolin C	Others	Others
Evofolin C is a Phenylpropanoids product that can be isolated from the barks of Cinnamomum cassia Presl .

HY-W037875

α-Acetamidocinnamic acid	Drug Derivative	Others
α-Acetamidocinnamic acid is a Alkaloids product that can be isolated from the barks of Cinnamomum cassia Presl .

HY-W015131

3-(4-(Dimethylamino)phenyl)acrylic acid	Drug Derivative	Others
3-(4-(Dimethylamino)phenyl)acrylic acid is a Alkaloids product that can be isolated from the barks of Cinnamomum cassia Presl .

HY-138213

Afzelechin-(4α→8)-epiafzelechin	Others	Others
Afzelechin-(4α→8)-epiafzelechin is a Flavonoids product that can be isolated from the herbs of Cassia javanica .

HY-N9961

2-Hydroxyl emodin-1-methyl ether	Others	Others
2-Hydroxyl emodin-1-methyl ether (Compound 5) is an anthraquinone that can be isolated from the seeds of Cassia obtusifolia .

HY-N9111

Bisabola-3,10-dien-2-one 1-Bisabolone	Others	Others
Bisabola-3,10-dien-2-one (1-Bisabolone) is a Phenylpropanoids product that can be isolated from the heartwoods of Cassia garrettiana .

HY-N1973R

Sennoside D (Standard)	Reference Standards Others	Infection Inflammation/Immunology
Sennoside D (Standard) is the analytical standard of Sennoside D. This product is intended for research and analytical applications. Sennoside D is an anthraquinone glycoside, found in leaves and pods of Senna (Cassia angustifolia) .

HY-N15709

Nor-Rubrofusarin gentiobioside	Bacterial	Infection
Nor-Rubrofusarin gentiobioside is a phenolic glycoside de-rubrofusarin that can be isolated from the seeds of Cassia tora. The same series of extracts of Nor-Rubrofusarin gentiobioside have antibacterial effects on Staphylococcus aureus strains .

HY-N7598

Chrysophanol-1-O-β-gentiobioside	Monoamine Oxidase	Neurological Disease
Chrysophanol-1-O-β-gentiobioside, an anthraquinone glycoside isolated from Cassia obtusifolia seeds. Chrysophanol-1-O-β-gentiobioside shows selective inhibition of hMAO-A isozyme activity (IC₅₀=96.15 μM) .

Cat. No.	Product Name	Category	Target	Chemical Structure