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cis-acting ligase ribozyme

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Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-145973B
    3'OMe-m7GpppAmpG Tris

    		Nucleoside Antimetabolite/Analog SARS-CoV Infection
    3'OMe-m7GpppAmpG (Tris) is a trinucleotide Cap1 analog with the structure m7 (3'OMeG)(5') ppp (5')(2'OMeA) pG, and also functions as a cis-acting ligase ribozyme inhibitor. 3'OMe-m7GpppAmpG (Tris) effectively reduces free 5'-triphosphate groups on RNA transcripts, thereby enabling efficient co-transcriptional capping of in vitro transcribed mRNA. 3'OMe-m7GpppAmpG (Tris) is not only widely used in the preparation of modified mRNA including trivalent influenza vaccine candidates, but also applicable to studies related to SARS-CoV-2 infection and other relevant research .
    3'OMe-m7GpppAmpG Tris

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