Scientific Reviews
Product Guides
Blogs
Topics
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
104 Results for "
complement C3
" in MedChemExpress (MCE) Product Catalog:
Products (104)
104 Results for "complement C3" in MCE Product Catalog:
13
13 Publications Verification
Synonyms: LNP023
Target:
Research Areas:
Iptacopan (LNP023) is an effective and orally-active highly selective factor B inhibitor with an IC50 value of 10 nM and KD of 7.9 nM. Iptacopan exerts a proximal effect in the complement cascade reaction, preventing the destruction (hemolysis) of red blood cells in PNH and the damage of renal cells in IgAN and C3G. Iptacopan can be used for the study of complement-mediated diseases, particularly paroxysmal nocturnal hemoglobinuria (PNH), primary immunoglobulin A nephropathy (IgAN), and complement 3 glomerulopathy (C3G) .
13
13 Publications Verification
Synonyms: LNP023 hydrochloride
Target:
Research Areas:
Iptacopan (LNP023) hydrochloride is an effective and orally-active highly selective factor B inhibitor with an IC50 value of 10 nM and KD of 7.9 nM. Iptacopan hydrochloride exerts a proximal effect in the complement cascade reaction, preventing the destruction (hemolysis) of red blood cells in PNH and the damage of renal cells in IgAN and C3G. Iptacopan hydrochloride can be used for the study of complement-mediated diseases, particularly paroxysmal nocturnal hemoglobinuria (PNH), primary immunoglobulin A nephropathy (IgAN), and complement 3 glomerulopathy (C3G) .
10
10 Cited Publications
Cat. No.: HY-P7863
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: C3; complement Component 3; complement C3; C3a Anaphylatoxin; CPAMD1; Prepro-C3; ARMD9; Epididymis Secretory Sperm Binding Protein Li 62p; C3a; Acylation-Stimulating Protein Cleavage Product; C3b; HEL-S-62p; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Co
Species:
Mouse
Source:
E. coli
9
9 Cited Publications
Target:
Research Areas:
JR14a is a potent thiophene antagonist of human complement C3a receptor. JR14a shows selectivity for the human C3a receptor over C5a receptor. JR14a can suppress C3aR-mediated inflammation .
9
Target:
Research Areas:
7
Target:
Research Areas:
7
Target:
Research Areas:
7
Target:
Research Areas:
7
7 Cited Publications
Cat. No.: HY-P7862
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: C3; complement Component 3; complement C3; C3a Anaphylatoxin; CPAMD1; Prepro-C3; ARMD9; Epididymis Secretory Sperm Binding Protein Li 62p; C3a; Acylation-Stimulating Protein Cleavage Product; C3b; HEL-S-62p; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Containing Protein 1; AHUS5; complement Component C3a; ASP; complement Component C3b
Species:
Human
Source:
E. coli
7
7 Cited Publications
Cat. No.: HY-P7695
Purity: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: C5; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Containing Protein 4; complement C5; C5a Anaphylatoxin; CPAMD4; Prepro-C5; complement Component 5; Anaphylatoxin C5a Analog; C5a; ECLZB; C5b; C5D
Species:
Mouse
Source:
E. coli
3
3 Cited Publications
Cat. No.: HY-P1036
CAS No.: 206645-99-0
Target:
Research Areas:
3
3 Cited Publications
Cat. No.: HY-P1036A
Target:
Research Areas:
2
2 Cited Publications
Cat. No.: HY-P3252A
Target:
Research Areas:
2
2 Cited Publications
Cat. No.: HY-N9481
CAS No.: 56411-57-5
2
2 Cited Publications
Cat. No.: HY-P1345A
Target:
Research Areas:
1
Target:
Research Areas:
1
Target:
Research Areas:
1
Target:
Research Areas:
1
1 Cited Publications
Cat. No.: HY-P78247
Purity: ≥ 95%, as determined by reducing SDS-PAGE or Bis-Tris PAGE.
Synonyms: C3; complement Component 3; complement C3; C3a Anaphylatoxin; CPAMD1; Prepro-C3; ARMD9; Epididymis Secretory Sperm Binding Protein Li 62p; C3a; Acylation-Stimulating Protein Cleavage Product; C3b; HEL-S-62p; C3 And PZP-Like Alpha-2-Macroglobulin Domain-Co
Species:
Mouse
Source:
HEK293
1
1 Cited Publications
Cat. No.: HY-P72137
Purity: ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: CFB; complement Factor B Preproprotein; Prev. BFD; Glycine-Rich Beta Glycoprotein; Prev. BF; C3 Proaccelerator; Properdin Factor B; C3 Proactivator; C3/C5 Convertase; ARMD14; H2-Bf; AHUS4; B-Factor, Properdin; FBI12; Properdin B; CFAB; PBF2; CFBD; GBG; FB
Species:
Mouse
Source:
E. coli
-
-
Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
