1. Immunology/Inflammation
  2. Complement System
  3. POT-4

POT-4 (Synonyms: AL-78898A)

Cat. No.: HY-P3204
Handling Instructions

POT-4 (AL-78898A), a Compstatin derivative, is a potent inhibitor of complement factor C3 activation. POT-4 can be used for age-related macular degeneration research

For research use only. We do not sell to patients.

Custom Peptide Synthesis

POT-4 Chemical Structure

POT-4 Chemical Structure

CAS No. : 934461-40-2

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Description

POT-4 (AL-78898A), a Compstatin derivative, is a potent inhibitor of complement factor C3 activation. POT-4 can be used for age-related macular degeneration research[1][2]

In Vitro

A derivative of compstatin, a potent C3 inhibitor, POT-4 is a cyclic peptide that exhibits binding activity to C3, preventing cleavage to its active fragments C3a and C3b[2].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

1627.85

Formula

C₇₂H₁₀₂N₂₂O₁₈S₂

CAS No.
Sequence Shortening

Ac-ICV{Trp(Me)}QDWGAHRCT-NH2 (Disulfide bridge:Cys2-Cys12)

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

POT-4AL-78898APOT4POT 4Complement SystemCompstatinC3age-relatedmaculardegenerationInhibitorinhibitorinhibit

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