8 Results for "

contraction of the uterus

" in MedChemExpress (MCE) Product Catalog:
Products (8)

8 Results for "contraction of the uterus" in MCE Product Catalog:

Cat. No.: HY-A0195
CAS No.: 58551-69-2
Research Areas:  

Endocrinology

Carboprost tromethamine is the synthetic 15-methyl analogue of prostaglandin F. Carboprost tromethamine can effectively promote law contraction of the uterus and significantly reduce the amount of bleeding during and after delivery .
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Cat. No.: HY-15008
CAS No.: 148927-60-0
Target:  

Oxytocin Receptor

Research Areas:  

Endocrinology

L-368,899 is an orally active and selective OT (oxytocin ) receptor antagonist, with IC50s of 8.9 and 26 nM for uterus of rat and human, respectively. L-368,899 can cross the blood-brain barrier (BBB). L-368,899 inhibits oxytocin-stimulated uterine contractions in rats and can be used in study of preterm labor .
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Cat. No.: HY-P1767
CAS No.: 111366-38-2
Target:  

PACAP Receptor

Research Areas:  

Cardiovascular Disease

Prepro VIP (81-122), human is a prepro-vasoactive intestinal polypeptide (VIP) derived peptide, corresponding to residues 81-122. Peptide histidine valine 42 (PHV-42) has been designated to correspond exactly to Prepro VIP (81-122), which reduces both the force and frequency of spontaneous contractions of isolated rat uterus .
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Cat. No.: HY-129278
CAS No.: 24185-51-1
Lunarine is an alkaloid, which can be isolated from the seeds of kale (Lunaria annua). Lunarine lowers the blood pressure, stimulates small intestinal motility, inhibits spontaneous contractions of uterus and nervous system, and exhibits an acute toxicity with LD50 of 62.3 mg/kg in dogs and rabbits. Lunarine exhibits antiparasitic activity through a competitive inhibition of protozoan oxidoreductase trypanothione reductase (TryR) with Ki of 304 μM .
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Cat. No.: HY-129266
CAS No.: 119953-19-4
Target:  

Drug Derivative

Research Areas:  

Endocrinology

NPC 573 is a Bradykinin (HY-P0206) analog. NPC 573 inhibits contraction of the uterus .
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Cat. No.: HY-A0195R
CAS No.: 58551-69-2
Research Areas:  

Endocrinology

Carboprost (tromethamine) (Standard) is the analytical standard of Carboprost (tromethamine). This product is intended for research and analytical applications. Carboprost tromethamine is the synthetic 15-methyl analogue of prostaglandin F. Carboprost tromethamine can effectively promote law contraction of the uterus and significantly reduce the amount of bleeding during and after delivery .
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Cat. No.: HY-A0252A
CAS No.: 15148-80-8
Target:  

Adrenergic Receptor

Research Areas:  

Cancer

Bupranolol hydrochloride is a non-selective β-adrenergic blocker with potent membrane stabilizing activity. Bupranolol hydrochloride is able to significantly modulate the contractile activity of the non-pregnant human uterus. Bupranolol hydrochloride showed significant effects on spontaneous uterine contractions in an in vitro study in patients with ovarian cancer. Bupranolol hydrochloride is similar in potency to propranolol, another β-adrenergic blocker. Bupranolol hydrochloride is rapidly and completely absorbed in vivo, and its major metabolite is carboxybupranolol .
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Cat. No.: HY-135446
CAS No.: 141595-53-1
Target:  

Endothelin Receptor

BQ-610 is a selective antagonist of the endothelin A receptor (ETA receptor). BQ-610 specifically blocks the ETA receptor, competitively inhibiting the binding of endothelin-1 (ET-1) (a vasoconstrictive peptide) to the receptor, thereby blocking the effects of ET-1 such as vascular smooth muscle contraction, cell mitosis, and inhibition of hormone secretion. BQ-610 significantly alleviates cerebral vasospasm in rabbits. BQ-610 blocks the bronchial epithelial and pulmonary vascular cell proliferation caused by cigarette smoke in rat models. BQ-610 can delay the natural luteal regression in the cow's uterus. BQ-610 can be used for research on vasospasm, abnormal cell proliferation, and reproductive endocrine disorders .
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