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contraction of the uterus

" in MedChemExpress (MCE) Product Catalog:

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天然物

製品番号 製品名 Target 研究分野 構造式
  • HY-A0195
    Carboprost tromethamine

    		Prostaglandin Receptor Endocrinology
    Carboprost tromethamine is the synthetic 15-methyl analogue of prostaglandin F2α. Carboprost tromethamine can effectively promote law contraction of the uterus and significantly reduce the amount of bleeding during and after delivery .
    Carboprost tromethamine
  • HY-15008
    L-368,899

    		Oxytocin Receptor Endocrinology
    L-368,899 is an orally active and selective OT (oxytocin ) receptor antagonist, with IC50s of 8.9 and 26 nM for uterus of rat and human, respectively. L-368,899 can cross the blood-brain barrier (BBB). L-368,899 inhibits oxytocin-stimulated uterine contractions in rats and can be used in study of preterm labor .
    L-368,899
  • HY-P1767
    Prepro VIP (81-122), human

    		PACAP Receptor Cardiovascular Disease
    Prepro VIP (81-122), human is a prepro-vasoactive intestinal polypeptide (VIP) derived peptide, corresponding to residues 81-122. Peptide histidine valine 42 (PHV-42) has been designated to correspond exactly to Prepro VIP (81-122), which reduces both the force and frequency of spontaneous contractions of isolated rat uterus .
    Prepro VIP (81-122), human
  • HY-129278
    Lunarine

    		Parasite Infection Cardiovascular Disease Neurological Disease
    Lunarine is an alkaloid, which can be isolated from the seeds of kale (Lunaria annua). Lunarine lowers the blood pressure, stimulates small intestinal motility, inhibits spontaneous contractions of uterus and nervous system, and exhibits an acute toxicity with LD50 of 62.3 mg/kg in dogs and rabbits. Lunarine exhibits antiparasitic activity through a competitive inhibition of protozoan oxidoreductase trypanothione reductase (TryR) with Ki of 304 μM .
    Lunarine
  • HY-129266
    NPC 573

    		Drug Derivative Endocrinology
    NPC 573 is a Bradykinin (HY-P0206) analog. NPC 573 inhibits contraction of the uterus .
    NPC 573
  • HY-A0195R
    Carboprost tromethamine (Standard)

    		Reference Standards Prostaglandin Receptor Endocrinology
    Carboprost (tromethamine) (Standard) is the analytical standard of Carboprost (tromethamine). This product is intended for research and analytical applications. Carboprost tromethamine is the synthetic 15-methyl analogue of prostaglandin F2α. Carboprost tromethamine can effectively promote law contraction of the uterus and significantly reduce the amount of bleeding during and after delivery .
    Carboprost tromethamine (Standard)
  • HY-A0252A
    Bupranolol hydrochloride

    		Adrenergic Receptor Cancer
    Bupranolol hydrochloride is a non-selective β-adrenergic blocker with potent membrane stabilizing activity. Bupranolol hydrochloride is able to significantly modulate the contractile activity of the non-pregnant human uterus. Bupranolol hydrochloride showed significant effects on spontaneous uterine contractions in an in vitro study in patients with ovarian cancer. Bupranolol hydrochloride is similar in potency to propranolol, another β-adrenergic blocker. Bupranolol hydrochloride is rapidly and completely absorbed in vivo, and its major metabolite is carboxybupranolol .
    Bupranolol hydrochloride
  • HY-135446
    BQ-610

    		Endothelin Receptor Cardiovascular Disease Endocrinology
    BQ-610 is a selective antagonist of the endothelin A receptor (ETA receptor). BQ-610 specifically blocks the ETA receptor, competitively inhibiting the binding of endothelin-1 (ET-1) (a vasoconstrictive peptide) to the receptor, thereby blocking the effects of ET-1 such as vascular smooth muscle contraction, cell mitosis, and inhibition of hormone secretion. BQ-610 significantly alleviates cerebral vasospasm in rabbits. BQ-610 blocks the bronchial epithelial and pulmonary vascular cell proliferation caused by cigarette smoke in rat models. BQ-610 can delay the natural luteal regression in the cow's uterus. BQ-610 can be used for research on vasospasm, abnormal cell proliferation, and reproductive endocrine disorders .
    BQ-610

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