2 Results for "

cotranslational protein translocation

" in MedChemExpress (MCE) Product Catalog:
Products (2)

2 Results for "cotranslational protein translocation" in MCE Product Catalog:

Cat. No.: HY-P3987A
Target:  

Sec61

Research Areas:  

Cancer

Cotransin TFA is a cyclic ester peptide and a Sec61 translocator binder with signal sequence-selective activity to inhibit co-translational protein translocation. Cotransin TFA inhibits the biogenesis of a subset of secretory and membrane proteins in a signal peptide-dependent manner. Cotransin TFA is applicable for cancer-related research .
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Cat. No.: HY-182690
CAS No.: 1883356-12-4
Target:  

HIV

Research Areas:  

Infection

CK147 is a Sec61α translocase inhibitor that blocks the co-translational translocation of proteins by binding to and inhibiting the Sec61 protein translocation channel on the endoplasmic reticulum membrane. CK147 exhibits potent CD4 downregulation activity with an IC50 of 0.04 µM. CK147 prevents HIV entry into host cells and shows significant cytotoxicity. CK147 can be used in studies related to HIV infection .
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