62 Results for "

cystine

" in MedChemExpress (MCE) Product Catalog:
Products (62)

62 Results for "cystine" in MCE Product Catalog:

878
878 Publications Verification
Cat. No.: HY-15763
CAS No.: 571203-78-6
Purity:  99.62%
Research Areas:  

Cancer

Erastin is a ferroptosis inducer. Erastin exhibits the mechanism of ferroptosis induction related to ROS and iron-dependent signaling. Erastin inhibits voltage-dependent anion channels (VDAC2/VDAC3) and accelerates oxidation, leading to the accumulation of endogenous reactive oxygen species. Erastin also disrupts mitochondrial permeability transition pore (mPTP) with anti-tumor activity. Furthermore, Erastin can block the uptake of cystine mediated by SLC7A11 and also spares UMRC6-EV and -C91A cells from disulfidptosis under glucose starvation .
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52
52 Cited Publications
Cat. No.: HY-114481
CAS No.: 1801530-11-9
Purity:  99.77%
Synonyms: IKE
Target:  

Ferroptosis

Research Areas:  

Cancer

Imidazole ketone erastin is a potent, selective, and metabolically stable inhibitor of the cystine-glutamate antiporter, system xc - and an activator of ferroptosis. Imidazole ketone erastin has anti-tumor activity .
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6
6 Cited Publications
Cat. No.: HY-139087
CAS No.: 1695533-44-8
Purity:  98.55%
Target:  

Ferroptosis

Research Areas:  

Metabolic Disease

Erastin2, an Erastin (HY-15763) analog, is a ferroptosis inducer and a potent, selective inhibitor of the system xc(-) cystine/glutamate transporter
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5
5 Cited Publications
Cat. No.: HY-N0394
CAS No.: 56-89-3
L-Cystine is an orally active extracellular form of L-Cysteine (HY-Y0337), occurring in proteins of plants and animals. L-Cystine elevates Nrf2 protein expression and activates Nrf2 transcription factor. L-cystine reduces ROS generation and protects against oxidant- or Doxorubicin (HY-15142A)-induced apoptosis. L-Cystine combined with L-theanine (HY-15121) enhances the production of antigen-specific IgG by increasing glutathione (GSH) levels and T helper 2 (Th2) mediated responses in mice. L-Cystine is promising for research of cystinuria and kidney stones
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5
5 Cited Publications
Cat. No.: HY-W009203
CAS No.: 30925-07-6
L-Cystine dihydrochloride is the dihydrochloride salt form of L-Cystine (HY-N0394). L-Cystine dihydrochloride elevates Nrf2 protein expression and activates Nrf2 transcription factor. L-cystine dihydrochloride reduces ROS generation and protects against oxidant- or Doxorubicin (HY-15142A)-induced apoptosis. L-Cystine dihydrochloride combined with L-theanine (HY-15121) enhances the production of antigen-specific IgG by increasing glutathione (GSH) levels and T helper 2 (Th2) mediated responses in mice. L-Cystine dihydrochloride is promising for research of cystinuria and kidney stones
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1
1 Cited Publications
Cat. No.: HY-B0373
CAS No.: 1953-02-2
Tiopronin is a diffusible antioxidant, an antidote to heavy metal poisoning and a radioprotective agent. Tiopronin can control the rate of cystine precipitation and excretion and has the potential for cystinuria, rheumatoid arthritis and hepatic disorders .
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1
1 Cited Publications
Cat. No.: HY-Y1147
CAS No.: 141-05-9
Synonyms: Maleic acid diethyl ester
Diethyl maleate (DEM) is an orally available, effective glutathione (GSH) depletor that crosses the blood-brain barrier. Diethyl maleate covalently binds irreversibly to GSH via glutathione S-transferase with an in vitro IC50 of 0.1-0.5 mM. Diethyl maleate selectively depletes GSH in liver, lung, and brain tissues, exacerbating oxidative stress and enhancing hyperbaric oxygen toxicity. Diethyl maleate promotes precursor amino acid uptake and in turn promotes GSH synthesis by upregulating the activity of the cystine-glutamate transporter XO -. Diethyl maleate can be used to study redox homeostasis and GSH protection mechanisms in oxidative stress-related diseases such as hyperbaric oxygen injury and metabolic diseases[1][2][3].
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1
1 Cited Publications
Cat. No.: HY-D1605
CAS No.: 1180490-57-6
BODIPY FL L-Cystine is a thiol-reactive, green-fluorescent dye. BODIPY FL L-Cystine can be the labeling of membrane proteins, proteins with hydrophobic binding sites, or hydrophobic ligands. (λex=504 nm, λem=511 nm) .
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1
1 Cited Publications
Cat. No.: HY-N0394S1
CAS No.: 1192736-38-1
L-Cystine-d4 is the deuterium labeled L-Cystine. L-Cystine is an amino acid and intracellular thiol, which plays a critical role in the regulation of cellular processes.
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1
1 Cited Publications
Cat. No.: HY-N0394S4
CAS No.: 2483736-13-4
L-Cystine-3,3'- 13C2 is the 13C labeled L-Cystine . L-Cystine is an amino acid and intracellular thiol, which plays a critical role in the regulation of cellular processes .
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1
1 Cited Publications
Cat. No.: HY-P80523
Synonyms: cystine/glutamate transporter, Amino acid transport system xc-, Calcium channel blocker resistance protein CCBR1, Solute carrier family 7 member 11, xCT, SLC7A11

Host:  

Mouse

Application:  

WB, IHC-P, ICC/IF, FC

Reactivity:  

Human, Mouse

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1
1 Cited Publications
Cat. No.: HY-P702444
Purity:  ≥ 90%, as determined by reducing SDS-PAGE.
Synonyms: SLC7A11; cystine/Glutamate Transporter; Solute Carrier Family 7 Member 11; Solute Carrier Family 7, (Cationic Amino Acid Transporter, Y+ System) Member 11; XCT; Uncharacterized Protein SLC7A11; Solute Carrier Family 7 (Anionic Amino Acid Transporter Light
Species:  
Source:  
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Cat. No.: HY-114348
CAS No.: 5545-17-5
Purity:  98.92%
Synonyms: DiNAC; (Ac-Cys-OH)2
Research Areas:  

Cardiovascular Disease

N,N'-diacetyl-L-cystine (DiNAC) is the disulphide dimer of N-acetylcysteine with immunomodulating properties. N,N'-diacetyl-L-cystine is a potent, orally active modulator of contact sensitivity/delayed type hypersensitivity reactions in rodents. N,N'-diacetyl-L-cystine also has antiatherosclerotic effects in Watanabe-heritable hyperlipidemic rabbit (WHHL) rabbits .
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Cat. No.: HY-W008876
CAS No.: 201531-88-6
Research Areas:  

Others

Fmoc-Pen(Trt)-OH is an amino acid derivative with an Fmoc protecting group that can be used to synthesize the inhibitory cystine knot (ICK) peptide ProTx-II .
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Cat. No.: HY-W001941
CAS No.: 349-46-2
Category:  

Microorganisms

D-Cystine is the D-enantiomer of L-Cystine. D-Cystine inhibits L-aspartate-β-semialdehyde dehydrogenase (ASADH) from Escherichia coli .
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Cat. No.: HY-W013940S1
CAS No.: 352431-53-9
DL-Cystine-d6 is the deuterium labeled DL-Cystine (HY-W013940). DL-Cystine is a cysteine derivative .
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Cat. No.: HY-W013940
CAS No.: 923-32-0
Research Areas:  

Others

DL-Cystine is a cysteine derivative .
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Cat. No.: HY-131516
CAS No.: 77591-18-5
Purity:  96.8%
Target:  

Drug Derivative

Research Areas:  

Metabolic Disease

Tiopronin-cysteine disulfide is a soluble disulfide metabolite/derivative of Tiopronin (HY-B0373) formed by reaction of Tiopronin with cystine. Tiopronin-cysteine disulfide reduces cystine crystal formation in cystinuria. Tiopronin-cysteine disulfide can be used for the research of cystinuria .
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Cat. No.: HY-W402682
CAS No.: 1695562-36-7
Research Areas:  

Neurological Disease Cancer

SXC2023 is a glutamatergic reagent and cystine-glutamate antiporter (System xc ) activator. SXC2023 can affect SLC7A11. SXC2023 is applicable to the research of colorectal cancer and trichotillomania .
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Cat. No.: HY-45609
CAS No.: 150465-29-5
L-Cysteine S-sulfate sodium hydrate is an S-sulfated derivative of L-cysteine (HY-Y0337). L-Cysteine S-sulfate sodium hydrate is the substrate for cystine lyase, it can be used in mass spectrometry and chromatography analyses .
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