SXC2023
Based on 1 Customer Validation
SXC2023 is a glutamatergic reagent and cystine-glutamate antiporter (System xc−) activator. SXC2023 can affect SLC7A11. SXC2023 is applicable to the research of colorectal cancer and trichotillomania.
For research use only. We do not sell to patients.
- Purity: 99.85%
- CAS No.: 1695562-36-7
- Formula: C13H15NO4S
- Molecular Weight:281.33
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
SXC2023 binds to the ferroptosis suppressor protein SLC7A11 with a binding energy of -6.2 kcal/mol via multiple hydrogen bond, pi-stacking, and alkyl interactions, indicating potential to modulate SLC7A11 function and sensitize colorectal cancer cells to ferroptosis[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 1695562-36-7
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Appearance Solid
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Molecular Weight 281.33
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Formula C13H15NO4S
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Color White to off-white
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SMILES
CC(N[C@H](C(O)=O)CSC(C1=CC=C(C=C1)C)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 125 mg/mL (444.32 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Ahmadizad Firouzjaei A, et al. Regulation of ferroptosis in colorectal cancer through therapeutic modulation and miRNA targeting. Biochem Biophys Rep. 2026;45:102444. Published 2026 Jan 8. [Content Brief]
[2]. CNS Summit: Selected Abstracts from the 2019 Meeting. Innov Clin Neurosci. 2019 Sep 1;16(9-10):S5-S19. [Content Brief]
[3]. Stein DJ, et al. Body-Focused Repetitive Behavior Disorders: From Competing Paradigms Toward Iterative Integration. Annu Rev Clin Psychol. 2026 May;22(1):481-503. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.5545 mL | 17.7727 mL | 35.5454 mL | 88.8636 mL |
| 5 mM | 0.7109 mL | 3.5545 mL | 7.1091 mL | 17.7727 mL | |
| 10 mM | 0.3555 mL | 1.7773 mL | 3.5545 mL | 8.8864 mL | |
| 15 mM | 0.2370 mL | 1.1848 mL | 2.3697 mL | 5.9242 mL | |
| 20 mM | 0.1777 mL | 0.8886 mL | 1.7773 mL | 4.4432 mL | |
| 25 mM | 0.1422 mL | 0.7109 mL | 1.4218 mL | 3.5545 mL | |
| 30 mM | 0.1185 mL | 0.5924 mL | 1.1848 mL | 2.9621 mL | |
| 40 mM | 0.0889 mL | 0.4443 mL | 0.8886 mL | 2.2216 mL | |
| 50 mM | 0.0711 mL | 0.3555 mL | 0.7109 mL | 1.7773 mL | |
| 60 mM | 0.0592 mL | 0.2962 mL | 0.5924 mL | 1.4811 mL | |
| 80 mM | 0.0444 mL | 0.2222 mL | 0.4443 mL | 1.1108 mL | |
| 100 mM | 0.0355 mL | 0.1777 mL | 0.3555 mL | 0.8886 mL |
SXC2023 Related Classifications
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