L-Cysteine S-sulfate sodium hydrate
Based on 1 Customer Validation
L-Cysteine S-sulfate sodium hydrate is an S-sulfated derivative of L-cysteine (HY-Y0337). L-Cysteine S-sulfate sodium hydrate is the substrate for cystine lyase, it can be used in mass spectrometry and chromatography analyses.
For research use only. We do not sell to patients.
- Purity : 98.0%
- CAS No.: 150465-29-5
- Formula: C3H7NO5S2.3/2H2O.Na
- Molecular Weight:251.24
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
Description
In Vitro
L-Cysteine S-sulfate sodium hydrate functions as an internal standard for HPLC-based quantification of L-cysteine S-oxygenation products in pooled female human hepatic cytosolic fractions[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 150465-29-5
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Appearance Solid
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Molecular Weight 251.24
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Formula C3H7NO5S2.3/2H2O.Na
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Color White to off-white
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SMILES
O=C(O[Na])[C@@H](N)CSS(=O)(O)=O.O.[3/2]
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
In Vitro:
H2O : 125 mg/mL (497.53 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Steventon GB, et al. Comparison of the sulfur-oxygenation of cysteine and S-carboxymethyl-l-cysteine in human hepatic cytosol and the rôle of cysteine dioxygenase. J Pharm Pharmacol. 2018;70(8):1069-1077. [Content Brief]
[2]. Macaluso V, et al. l-Cysteine Modified by S-Sulfation: Consequence on Fragmentation Processes Elucidated by Tandem Mass Spectrometry and Chemical Dynamics Simulations. J Phys Chem A. 2019;123(17):3685-3696. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 3.9803 mL | 19.9013 mL | 39.8026 mL | 99.5064 mL |
| 5 mM | 0.7961 mL | 3.9803 mL | 7.9605 mL | 19.9013 mL | |
| 10 mM | 0.3980 mL | 1.9901 mL | 3.9803 mL | 9.9506 mL | |
| 15 mM | 0.2654 mL | 1.3268 mL | 2.6535 mL | 6.6338 mL | |
| 20 mM | 0.1990 mL | 0.9951 mL | 1.9901 mL | 4.9753 mL | |
| 25 mM | 0.1592 mL | 0.7961 mL | 1.5921 mL | 3.9803 mL | |
| 30 mM | 0.1327 mL | 0.6634 mL | 1.3268 mL | 3.3169 mL | |
| 40 mM | 0.0995 mL | 0.4975 mL | 0.9951 mL | 2.4877 mL | |
| 50 mM | 0.0796 mL | 0.3980 mL | 0.7961 mL | 1.9901 mL | |
| 60 mM | 0.0663 mL | 0.3317 mL | 0.6634 mL | 1.6584 mL | |
| 80 mM | 0.0498 mL | 0.2488 mL | 0.4975 mL | 1.2438 mL | |
| 100 mM | 0.0398 mL | 0.1990 mL | 0.3980 mL | 0.9951 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Keywords
- L-Cysteine S-sulfate sodium
- 150465-29-5
- Drug Derivative
- human hepatic cytosolic fractions
- L-cysteine
- quantum chemistry calculations
- deprotonated L-cysteine sulfenic acid
- L-cysteine sulfinic acid
- HPLC
- L-cysteic acid
- in vitro enzyme assays
- low-energy collision-induced dissociation
- ion-neutral complex
- Inhibitor
- inhibitor
- inhibit