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euphorbiaceae

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Bacterial (1) Collagen (1) Fungal (1)
By Research Areas:	Infection (1) Metabolic Disease (1) Neurological Disease (1)

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Natural
Products

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-N1652

2,3,8-Tri-O-methylellagic acid 3,3′,4-Tri-O-methylellagic acid	Others	Others
2,3,8-Tri-O-methylellagic acid is a terpenoids that can be isolated from the stem bark of Neoboutonia macrocalyx. 2,3,8-Tri-O-methylellagic acid is found to be 50 times more active than the parent ellagic acid .

HY-125116

Jatrophane 2	Others	Others
Jatrophane 2 is a kind of jatrophane diterpene polyester that can be isolated from the highly irritant extract of whole fresh plants of E. peplus L. (Euphorbiaceae) .

HY-125115

Jatrophane 3	Others	Others
Jatrophane 3 is a kind of jatrophane diterpene polyester that can be isolated from the highly irritant extract of whole fresh plants of E. peplus L. (Euphorbiaceae) .

HY-N3952

Glochidonol	Others	Others
Glochidonol is a triterpene ketol that can be isolated from the stems of Glochidion wrightii Benth (Euphorbiaceae) .

HY-N12345

5-Dexyexcoecafolin B	Others	Others
5-Dexyexcoecafolin B is a tigliane-type diterpenoid isolated from the EtOAc extract of Excoecaria acerifolia Didr. 5-Dexyexcoecafolin B has anti-HIV-1 activity with a EC₅₀ value of 0.036 μM .

HY-N3970

Gopherenediol	Others	Neurological Disease
Gopherenediol is a diterpenoid with putative antifeedant activity against Mammalian herbivores. Gopherenediol is the active compound in to form deterrent effect, protects gopherweed, Euphorbia lathyris (Euphorbiaceae) from feeding by Mammalian herbivores .

HY-N12752

(-)-Casbene Casbene	Bacterial Fungal	Infection
(-)-Casbene (Casbene) is an antimicrobial agent that can be found in Euphorbiaceae plants. (-)-Casbene retards Aspergillus niger development, and inhibits Escherichia coli growth. (-)-Casbene can be used for the research of bacterial and fungal infection .

HY-N13822

Trigothysoid P	Others	Others
Trigothysoid P is a daphnane-type diterpenoid compound that can be used in antiviral and natural product chemistry research. Trigothysoid P can be extracted from the dried branches and leaves of Trigonostemon thyrsoideum (a plant of the Euphorbiaceae family, genus Trigonostemon) .

HY-N11736

12-O-Tiglyl-phorbol 13-dodecanoate	Collagen	Metabolic Disease
12-O-Tiglyl-phorbol 13-dodecanoate (TD13) is a potential inhibitor with anti-hepatic fibrosis activity, and it belongs to a series of derivatives of oral APOL2 inhibitors and anti-hepatic fibrosis agents. It shows no obvious toxicity in preclinical models. Compounds of the 12-O-Tiglyl-phorbol 13-dodecanoate series inhibit the expression of fibronectin, type I collagen and α-smooth muscle actin in hepatic stellate cells. 12-O-Tiglyl-phorbol 13-dodecanoate can be isolated from the Euphorbiaceae plant Euphorbia fischeriana, and it is applicable to the research of hepatic fibrosis .

2,3,8-Tri-O-methylellagic acid 3,3′,4-Tri-O-methylellagic acid	Monophenols Classification of Application Fields Neoboutonia macrocalyx Pax Other Diseases Phenols Euphorbiaceae Plants Disease Research Fields Source Classification	Others
2,3,8-Tri-O-methylellagic acid is a terpenoids that can be isolated from the stem bark of Neoboutonia macrocalyx. 2,3,8-Tri-O-methylellagic acid is found to be 50 times more active than the parent ellagic acid .

Jatrophane 2	Structural Classification Terpenoids Euphorbia peplus Linn. Diterpenoids Euphorbiaceae Plants Source Classification	Others
Jatrophane 2 is a kind of jatrophane diterpene polyester that can be isolated from the highly irritant extract of whole fresh plants of E. peplus L. (Euphorbiaceae) .

Jatrophane 3	Terpenoids Euphorbia peplus Linn. Diterpenoids Euphorbiaceae Plants Source Classification	Others
Jatrophane 3 is a kind of jatrophane diterpene polyester that can be isolated from the highly irritant extract of whole fresh plants of E. peplus L. (Euphorbiaceae) .

Glochidonol	Triterpenes Structural Classification Dianthus chinensis L. Terpenoids Plants Pentacyclic Triterpenoids Caryophyllaceae Source Classification	Others
Glochidonol is a triterpene ketol that can be isolated from the stems of Glochidion wrightii Benth (Euphorbiaceae) .

5-Dexyexcoecafolin B	Triterpenes Excoecaria acertiflia Didr Terpenoids Euphorbiaceae Plants Source Classification	Others
5-Dexyexcoecafolin B is a tigliane-type diterpenoid isolated from the EtOAc extract of Excoecaria acerifolia Didr. 5-Dexyexcoecafolin B has anti-HIV-1 activity with a EC₅₀ value of 0.036 μM .

Gopherenediol	Terpenoids Euphorbia lathylris Linnaeus Diterpenoids Euphorbiaceae Plants Source Classification	Others
Gopherenediol is a diterpenoid with putative antifeedant activity against Mammalian herbivores. Gopherenediol is the active compound in to form deterrent effect, protects gopherweed, Euphorbia lathyris (Euphorbiaceae) from feeding by Mammalian herbivores .

(-)-Casbene Casbene	Structural Classification Ricinus communis L. Terpenoids Diterpenoids Euphorbiaceae Plants Source Classification	Bacterial Fungal
(-)-Casbene (Casbene) is an antimicrobial agent that can be found in Euphorbiaceae plants. (-)-Casbene retards Aspergillus niger development, and inhibits Escherichia coli growth. (-)-Casbene can be used for the research of bacterial and fungal infection .

Trigothysoid P	Structural Classification Terpenoids Diterpenoids Euphorbiaceae Plants Trigonostemon thyrsoideus Stapf Source Classification	Others
Trigothysoid P is a daphnane-type diterpenoid compound that can be used in antiviral and natural product chemistry research. Trigothysoid P can be extracted from the dried branches and leaves of Trigonostemon thyrsoideum (a plant of the Euphorbiaceae family, genus Trigonostemon) .

12-O-Tiglyl-phorbol 13-dodecanoate	Structural Classification Natural Products Euphorbia fischeriana Steud. Euphorbiaceae Plants Source Classification	Collagen
12-O-Tiglyl-phorbol 13-dodecanoate (TD13) is a potential inhibitor with anti-hepatic fibrosis activity, and it belongs to a series of derivatives of oral APOL2 inhibitors and anti-hepatic fibrosis agents. It shows no obvious toxicity in preclinical models. Compounds of the 12-O-Tiglyl-phorbol 13-dodecanoate series inhibit the expression of fibronectin, type I collagen and α-smooth muscle actin in hepatic stellate cells. 12-O-Tiglyl-phorbol 13-dodecanoate can be isolated from the Euphorbiaceae plant Euphorbia fischeriana, and it is applicable to the research of hepatic fibrosis .

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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euphorbiaceae

Inhibitors & Agonists

NaturalProducts

Natural
Products