1. 天然物
  2. Disease Research Fields Plants Phenols
  3. Euphorbiaceae Other Diseases Monophenols
  4. Neoboutonia macrocalyx Pax
  5. 2,3,8-Tri-O-methylellagic acid

2,3,8-Tri-O-methylellagic acid  (Synonyms: 3,3′,4-Tri-O-methylellagic acid)

製品番号: HY-N1652 純度: 97.0%
COA 取扱説明書 Technical Support

2,3,8-Tri-O-methylellagic acid is a terpenoids that can be isolated from the stem bark of Neoboutonia macrocalyx. 2,3,8-Tri-O-methylellagic acid is found to be 50 times more active than the parent ellagic acid.

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2,3,8-Tri-O-methylellagic acid

2,3,8-Tri-O-methylellagic acid 構造式

CAS 番号 : 1617-49-8

容量 価格(税別) 在庫状況 数量
1 mg $516 在庫あり
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製品説明

2,3,8-Tri-O-methylellagic acid is a terpenoids that can be isolated from the stem bark of Neoboutonia macrocalyx. 2,3,8-Tri-O-methylellagic acid is found to be 50 times more active than the parent ellagic acid[1][2].

Cellular Effect
Cell Line Type Value Description References
Col2 ED50
>5 μg/mL
Compound: 10
Cytotoxicity against human Col2 cells after 72 hrs by sulforhodamine B assay
Cytotoxicity against human Col2 cells after 72 hrs by sulforhodamine B assay
[PMID: 18271551]
HT-29 IC50
>10 μM
Compound: S3
Cytotoxicity against human HT-29 cells assessed as reduction in cell viability after 72 hrs by CellTiter 96 aqueous one solution assay
Cytotoxicity against human HT-29 cells assessed as reduction in cell viability after 72 hrs by CellTiter 96 aqueous one solution assay
[PMID: 30057155]
HT-29 IC50
>10 μM
Compound: S3
Inhibition of mitochondrial membrane potential in human HT-29 cells after 3 hrs by JC-1 staining based fluorescence assay
Inhibition of mitochondrial membrane potential in human HT-29 cells after 3 hrs by JC-1 staining based fluorescence assay
[PMID: 30057155]
KB ED50
>5 μg/mL
Compound: 10
Cytotoxicity against human KB cells after 72 hrs by sulforhodamine B assay
Cytotoxicity against human KB cells after 72 hrs by sulforhodamine B assay
[PMID: 18271551]
Lu1 ED50
>5 μg/mL
Compound: 10
Cytotoxicity against human Lu1 cells after 72 hrs by sulforhodamine B assay
Cytotoxicity against human Lu1 cells after 72 hrs by sulforhodamine B assay
[PMID: 18271551]
MCF7 ED50
>5 μg/mL
Compound: 10
Cytotoxicity against human MCF7 cells after 72 hrs by sulforhodamine B assay
Cytotoxicity against human MCF7 cells after 72 hrs by sulforhodamine B assay
[PMID: 18271551]
MDA-MB-435 IC50
>10 μM
Compound: S3
Cytotoxicity against human MDA-MB-435 cells assessed as reduction in cell viability after 72 hrs by CellTiter 96 aqueous one solution assay
Cytotoxicity against human MDA-MB-435 cells assessed as reduction in cell viability after 72 hrs by CellTiter 96 aqueous one solution assay
[PMID: 30057155]
OVCAR-3 IC50
>10 μM
Compound: S3
Cytotoxicity against human OVCAR3 cells assessed as reduction in cell viability after 72 hrs by CellTiter 96 aqueous one solution assay
Cytotoxicity against human OVCAR3 cells assessed as reduction in cell viability after 72 hrs by CellTiter 96 aqueous one solution assay
[PMID: 30057155]
P388 ED50
>5 μg/mL
Compound: 10
Cytotoxicity against mouse P388 cells after 72 hrs by sulforhodamine B assay
Cytotoxicity against mouse P388 cells after 72 hrs by sulforhodamine B assay
[PMID: 18271551]
分子量

344.27

分子式

C17H12O8

CAS 番号
Appearance

Solid

Color

White to off-white

SMILES

O=C1C2=CC(OC)=C(OC)C(O3)=C2C4=C(C3=O)C=C(O)C(OC)=C4O1

Structure Classification
Initial Source
輸送条件

Room temperature in continental US; may vary elsewhere.

保管条件

-20°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

純度とドキュメンテーション
参考文献
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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製品名:
2,3,8-Tri-O-methylellagic acid
製品番号:
HY-N1652
数量:
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