42 Results for "

exercise

" in MedChemExpress (MCE) Product Catalog:
Products (42)

42 Results for "exercise" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-150012
CAS No.: 183241-73-8
Purity:  99.94%
Synonyms: Lac-Phe
N-Lactoyl-phenylalanine, a N-lactoyl-amino acid, is a blood-derived signaling metabolite that can be induced by exercise. N-Lactoyl-phenylalanine can reduce obesity and improve glucose tolerance .
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2
2 Cited Publications
Cat. No.: HY-109121
CAS No.: 1345410-31-2
Purity:  99.63%
Synonyms: CK-2127107
Target:  

Calcium Channel

Research Areas:  

Cardiovascular Disease

Reldesemtiv (CK-2127107) is a selective, orally active and next-generation fast skeletal muscle troponin activator (FSTA). Reldesemtiv selectively activates fast skeletal myofibrils with an EC50 of 3.4 μM. Reldesemtiv increases exercise performance in a heart failure model .
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2
2 Cited Publications
Cat. No.: HY-15344
CAS No.: 1208313-97-6
Purity:  ≥95.0%
Ketone monoester is an orally available ketone monoester that serves as a source of nutritional ketones. Ketone monoester increases plasma beta-hydroxybutyrate, acetoacetate, blood glucose, blood sodium, and blood creatinine levels in mouse models. Ketone monoester has the potential to improve athletic performance and endurance in animals. Ketone monoester partially prevents myasthenia in septic mice. Ketone monoester may also be used to study Parkinson's disease or diabetes .
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1
1 Cited Publications
Cat. No.: HY-113380
CAS No.: 4249-19-8
Purity:  ≥98.0%
(S)-β-Aminoisobutyric acid is an orally active S-isomer of β-Aminoisobutyric acid (HY-W012974). (S)-β-Aminoisobutyric acid can be produced through the catabolism of thymine and valine. (S)-β-Aminoisobutyric acid reduces apoptosis and increases the ratio of p-AMPK. (S)-β-Aminoisobutyric acid has cardioprotective effects. (S)-β-Aminoisobutyric acid is associated with acute aerobic exercise .
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1
1 Cited Publications
Cat. No.: HY-P2048A
MOTS-c (human) acetate is a blood-brain barrier-penetrating, mitochondrial-derived peptide that modulates the AMPK/PGC-1α pathway to enhance insulin sensitivity. MOTS-c (human) acetate inhibits the folate cycle and de novo purine synthesis, increases AICAR levels to activate AMPK, and then regulates the Nrf2/Keap1 antioxidant pathway and inhibits the NF-κB inflammatory pathway, while promoting mitochondrial biogenesis and energy metabolism. MOTS-c (human) acetate has the effects of improving glucose and lipid metabolism, anti-oxidative stress, anti-inflammatory and neuroprotection, and can be used in the study of type 2 diabetes, traumatic brain injury, inflammatory diseases and aging-related metabolic disorders .
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1
1 Cited Publications
Cat. No.: HY-W023323
CAS No.: 925704-45-6
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

(S)-β-Aminoisobutyric acid hydrochloride is a cytoprotective agent, which is a non-proteinogenic amino acid enantiomer derived from valine metabolism in skeletal muscle mitochondria. The plasma level of (S)-β-Aminoisobutyric acid hydrochloride increases significantly after acute aerobic exercise (and is not affected by the AGXT2 rs37369 genotype), and it is secreted by mouse extensor digitorum longus and soleus muscles in ex vivo contraction assays. (S)-β-Aminoisobutyric acid hydrochloride specifically protects osteocytes from oxidative stress-induced cell death .
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Cat. No.: HY-W012241
CAS No.: 693-23-2
Dodecanedioic acid is an orally active straight-chain dicarboxylic acid. As an alternative energy substrate between lipids and carbohydrates, Dodecanedioic acid can be rapidly oxidized during exercise, reducing muscle fatigue without stimulating insulin secretion. Dodecanedioic acid also exhibits blood glucose-lowering activity in non-insulin-dependent diabetes mellitus .
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Cat. No.: HY-30216A
CAS No.: 498-36-2
Synonyms: α-Hydroxyisocaproic acid
Leucic acid (α-Hydroxyisocaproic acid) is an orally active end-product of the microbial metabolism of leucine. Leucic acid can bind to HCAR2, alters AMPK and ERK1/2 phosphorylation status, suppresses lipid synthesis, promotes catabolism, reduces adiposity, enhances lean mass and exercise capacity. Leucic acid suppresses pro-inflammatory cytokine secretion, inflammation-related gene mRNA expression. Leucic acid decreases basal protein synthesis, attenuates myotube atrophy. Leucic acid can be used for the research of obesity .
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Cat. No.: HY-17428
CAS No.: 154-69-8
Tripelennamine hydrochloride is a histamine H1-receptor antagonist. Tripelennamine hydrochloride effectively reverses histamine-induced bronchoconstriction, increased transpulmonary pressure, elevated pulmonary vascular resistance and reduced dynamic compliance. Tripelennamine hydrochloride does not significantly affect arterial hypoxemia, hemoglobin desaturation and hypercapnia in horses undergoing short-term high-intensity exercise. Tripelennamine hydrochloride exhibits local and central analgesic activity. Tripelennamine hydrochloride can be used in studies related to emphysema, urticaria and acute laminitis .
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Cat. No.: HY-P991083
Synonyms: Arumakimig

Target:  

Interleukin Related

Research Areas:  

Infection Inflammation/Immunology

MAS825 (Arumakimig) is a bispecific monoclonal antibody targeting IL-1β and IL-18. MAS825 reduces inflammatory infiltration and pulmonary alveolar proteinosis, and improves blood oxygen saturation, exercise tolerance and quality of life. MAS825 also promotes viral clearance. MAS825 can be used in research related to systemic juvenile idiopathic arthritis complicated with interstitial lung disease or macrophage activation syndrome, as well as COVID-19 .
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Cat. No.: HY-158110
CAS No.: 848127-67-3
Purity:  99.77%
Target:  

TRP Channel

Research Areas:  

Inflammation/Immunology

Phenylcapsaicin is an analogue of Capsaicin (HY-10448). Phenylcapsaicin is a TRPV1 receptor activator. Phenylcapsaicin enhances fat oxidation during aerobic exercise .
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Cat. No.: HY-150012S1
Synonyms: Lac-Phe-13C6
N-Lactoyl-phenylalanine- 13C6 (Lac-Phe- 13C6) is 13C labeled N-Lactoyl-phenylalanine. N-Lactoyl-phenylalanine, a N-lactoyl-amino acid, is a blood-derived signaling metabolite that can be induced by exercise. N-Lactoyl-phenylalanine can reduce obesity and improve glucose tolerance .
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Cat. No.: HY-152006S
CAS No.: 2692623-94-0
Propionyl-L-carnitine-d3 (hydrochloride) is deuterium labeled Propionyl-L-carnitine. Propionyl-L-carnitine is a carnitine derivative and has a high affinity for muscular carnitine transferase. Propionyl-L-carnitine increases cellular carnitine content, thereby allowing free fatty acid transport into the mitochondria. Propionyl-L-carnitine alleviates the symptoms of PAD through a metabolic pathway, thereby improving exercise performance .
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Cat. No.: HY-107928A
CAS No.: 9004-66-4
Iron-Dextran is an injectable complex of iron and dextran, a complex carbohydrate. It is often used to improve iron deficiency anemia, a condition characterized by low levels of iron in the blood due to insufficient dietary intake or malabsorption. Iron-glucan works by providing a source of supplemental iron that the body can use to produce hemoglobin, the protein responsible for carrying oxygen in the blood. However, caution should be exercised when taking iron dextran because it may cause hypersensitivity reactions, including anaphylaxis, and may also increase the risk of infection or other adverse reactions. Therefore, it should only be administered under the supervision of a qualified healthcare provider in a clinical setting.
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Cat. No.: HY-W012241S1
CAS No.: 97543-02-7
Dodecanedioic acid-d4 is the deuterium labeled Dodecanedioic acid (HY-W012241). Dodecanedioic acid is an orally active straight-chain dicarboxylic acid. As an alternative energy substrate between lipids and carbohydrates, Dodecanedioic acid can be rapidly oxidized during exercise, reducing muscle fatigue without stimulating insulin secretion. Dodecanedioic acid also exhibits blood glucose-lowering activity in non-insulin-dependent diabetes mellitus .
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Cat. No.: HY-W012241R
CAS No.: 693-23-2
Dodecanedioic acid (Standard) is the analytical standard of Dodecanedioic acid (HY-W012241). This product is intended for research and analytical applications. Dodecanedioic acid is an orally active straight-chain dicarboxylic acid. As an alternative energy substrate between lipids and carbohydrates, Dodecanedioic acid can be rapidly oxidized during exercise, reducing muscle fatigue without stimulating insulin secretion. Dodecanedioic acid also exhibits blood glucose-lowering activity in non-insulin-dependent diabetes mellitus .
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Cat. No.: HY-N2361
CAS No.: 18286-71-0
Target:  

Others

N-Benzyllinoleamide can be isolated from Lepidium meyenii Walp., has pharmaceutical property against exercise-induced fatigue .
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Cat. No.: HY-Y1150
CAS No.: 75-98-9
Synonyms: Trimethylmethanecarboxylic acid; Versatic 5 acid; tert-Pentanoic acid
Target:  

Antibiotic

Research Areas:  

Inflammation/Immunology

Pivalic acid (Trimethylmethanecarboxylic acid) is a carboxylic acid. Pivalic acid induces Carnitine deficiency. Pivalic acid conjugated with Antibiotics, such as Pivmecillinam (HY-B0810) and Pivampicillin (HY-119011), are used in urinary tract infection. Pivalic acid can be used in physical exercise research .
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Cat. No.: HY-B2202R
CAS No.: 77-91-8
Research Areas:  

Others

Choline dihydrogen citrate (Standard) is the analytical standard of Choline dihydrogen citrate. This product is intended for research and analytical applications. Choline dihydrogen citrate is a choline-rich hydrochloride that can be absorbed by the body and converted into acetylcholine, which enhances the function of the nervous system and muscles and promotes good health. In addition, this compound is widely used in supplements such as certain energy drinks and protein powders to help improve the body's metabolism and exercise capacity.
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Cat. No.: HY-19596
CAS No.: 75184-94-0
Research Areas:  

Inflammation/Immunology

Fenprinast is a cromotyn-like bronchodilator used for the research of allergy and exercise-induced asthma. Fenprinast has oral bioactivity .
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