1. GPCR/G Protein
    Neuronal Signaling
    Immunology/Inflammation
    Metabolic Enzyme/Protease
  2. Histamine Receptor
    Endogenous Metabolite
  3. Tripelennamine hydrochloride

Tripelennamine hydrochloride 

Cat. No.: HY-17428 Purity: 99.90%
COA Handling Instructions

Tripelennamine hydrochloride, an ethylenediamine derivative, is a potent histamine H1-receptor antagonist. Tripelennamine hydrochloride lessens the allergic response of the organism caused by histamine. Tripelennamine hydrochloride can be used for the research of rhinitis, conjunctivitis, and allergic and anaphylactic reactions.

For research use only. We do not sell to patients.

Tripelennamine hydrochloride Chemical Structure

Tripelennamine hydrochloride Chemical Structure

CAS No. : 154-69-8

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply Now  
Solution
10 mM * 1 mL in DMSO USD 92 In-stock
Estimated Time of Arrival: December 31
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
USD 92 In-stock
Estimated Time of Arrival: December 31
Solid
100 mg USD 84 In-stock
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200 mg USD 132 In-stock
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500 mg USD 228 In-stock
Estimated Time of Arrival: December 31
1 g USD 312 In-stock
Estimated Time of Arrival: December 31
5 g USD 624 In-stock
Estimated Time of Arrival: December 31
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Description

Tripelennamine hydrochloride, an ethylenediamine derivative, is a potent histamine H1-receptor antagonist. Tripelennamine hydrochloride lessens the allergic response of the organism caused by histamine. Tripelennamine hydrochloride can be used for the research of rhinitis, conjunctivitis, and allergic and anaphylactic reactions[1][2][3].

Molecular Weight

291.82

Formula

C16H22ClN3

CAS No.
SMILES

CN(C)CCN(CC1=CC=CC=C1)C2=NC=CC=C2.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (342.68 mM; Need ultrasonic)

DMSO : 25 mg/mL (85.67 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.4268 mL 17.1338 mL 34.2677 mL
5 mM 0.6854 mL 3.4268 mL 6.8535 mL
10 mM 0.3427 mL 1.7134 mL 3.4268 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (8.57 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (8.57 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (8.57 mM); Clear solution

*All of the co-solvents are available by MCE.
Purity & Documentation
References
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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× = ×
C1   V1   C2   V2

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Product Name:
Tripelennamine hydrochloride
Cat. No.:
HY-17428
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