4249-19-8
Chemical Structure
(S)-β-Aminoisobutyric acid
- CAS No.: 4249-19-8
- Formula:C4H9NO2
- Molecular Weight:103.12
IUPAC Name: (S)-3-amino-2-methylpropanoic acid
InChIKey: QCHPKSFMDHPSNR-VKHMYHEASA-N
SMILES: O=C(O)[C@@H](C)CN
Biological Activity: (S)-β-Aminoisobutyric acid is an orally active S-isomer of β-Aminoisobutyric acid (HY-W012974). (S)-β-Aminoisobutyric acid can be produced through the catabolism of thymine and valine. (S)-β-Aminoisobutyric acid reduces apoptosis and increases the ratio of p-AMPK. (S)-β-Aminoisobutyric acid has cardioprotective effects. (S)-β-Aminoisobutyric acid is associated with acute aerobic exercise[1][2][3].
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(S)-β-Aminoisobutyric acid | 99.59% | (S)-β-Aminoisobutyric acid is an orally active S-isomer of β-Aminoisobutyric acid (HY-W012974). (S)-β-Aminoisobutyric acid can be produced through the catabolism of thymine and valine. (S)-β-Aminoisobutyric acid reduces apoptosis and increases the ratio of p-AMPK. (S)-β-Aminoisobutyric acid has cardioprotective effects. (S)-β-Aminoisobutyric acid is associated with acute aerobic exercise. | ||||||||||||||||||||
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(S)-β-Aminoisobutyric acid (Standard) | ≥98% | (S)-β-Aminoisobutyric acid (Standard) is the analytical standard of (S)-β-Aminoisobutyric acid. This product is intended for research and analytical applications. (S)-β-Aminoisobutyric acid is a non-protein amino acid originating from the catabolism of thymine and valine. | ||||||||||||||||||||
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- [1]. CRUMPLER HR, et al. beta-Aminoisobutyric acid (alpha-methyl-beta-alanine); a new amino-acid obtained from human urine. Nature. 1951 Feb 24;167(4243):307-8. [Content Brief]
- [2]. Yu Y, et al. Exercise-Generated β-Aminoisobutyric Acid (BAIBA) Reduces Cardiomyocyte Metabolic Stress and Apoptosis Caused by Mitochondrial Dysfunction Through the miR-208b/AMPK Pathway. Front Cardiovasc Med. 2022 Feb 25;9:803510. [Content Brief]
- [3]. Stautemas J, et al. Acute Aerobic Exercise Leads to Increased Plasma Levels of R- and S-β-Aminoisobutyric Acid in Humans. Front Physiol. 2019 Sep 25;10:1240. [Content Brief]