Pivalic acid
Based on 1 Customer Validation
Pivalic acid (Trimethylmethanecarboxylic acid) is a carboxylic acid. Pivalic acid induces Carnitine deficiency. Pivalic acid conjugated with Antibiotics, such as Pivmecillinam (HY-B0810) and Pivampicillin (HY-119011), are used in urinary tract infection. Pivalic acid can be used in physical exercise research.
For research use only. We do not sell to patients.
- Purity: 99.93%
- CAS No.: 75-98-9
- Formula: C5H10O2
- Molecular Weight:102.13
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Hepatocyte | EC50 |
5.53 μM
Compound: 9
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Reduction of propionyl-CoA in human hepatocytes derived from propionic acidemia patient pretreated for 30 mins followed by 13C-isoleucine addition and measured after 1 hr by MS/MS analysis
Reduction of propionyl-CoA in human hepatocytes derived from propionic acidemia patient pretreated for 30 mins followed by 13C-isoleucine addition and measured after 1 hr by MS/MS analysis
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[PMID: 33848153] |
| K562 | IC50 |
4.5 mM
Compound: Pivalic acid
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Inhibition of cell growth against human myeloid leukemia K562(S) cells
Inhibition of cell growth against human myeloid leukemia K562(S) cells
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[PMID: 10560743] |
Chemical Information
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CAS No. 75-98-9
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Appearance Solid-Liquid Mixture
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Molecular Weight 102.13
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Formula C5H10O2
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Color White to off-white
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SMILES
CC(C)(C)C(O)=O
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Synonyms
Trimethylmethanecarboxylic acid; Versatic 5 acid; tert-Pentanoic acid
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Purity & Documentation
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Data Sheet (265 KB)
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SDS (476 KB)
- English - EN (476 KB)
- Français - FR (476 KB)
- Deutsch - DE (476 KB)
- Norwegian - NO (476 KB)
- Español - ES (476 KB)
- Swedish - SV (476 KB)
- Italian - IT (476 KB)
- Korean - KR (476 KB)
- Portuguese - PT (476 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pivalic acid Related Classifications
HY-Y1150 Related Classifications
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- Pivalic acid
- 75-98-9
- Trimethylmethanecarboxylic acid
- Versatic 5 acid
- tert-Pentanoic acid
- Antibiotic
- skeletal muscle glycogen consumption
- carnitine ester formation
- hepatic fatty acid oxidation
- healthy adults
- substrate metabolism
- carnitine deficiency
- left ventricular mass
- ketone body production
- urinary carnitine excretion
- bodily carnitine depletion
- Inhibitor
- inhibitor
- inhibit