Search Result

Results for "

fatty acyls

" in MedChemExpress (MCE) Product Catalog:

By Targets:	FAAH (1) FATP (1) Fatty Acid Synthase (FASN) (4) ACSL Family (2) Acyltransferase (2) Antibiotic (6) Apoptosis (5) Bacterial (11) Biochemical Assay Reagents (267) Cannabinoid Receptor (1) Carnitine Palmitoyltransferase (CPT) (1) DNA/RNA Synthesis (1) Drug Derivative (3) Drug Intermediate (1) Endogenous Metabolite (49) Environmental Pollutants (1) Ferroptosis (1) Fluorescent Dye (1) Fungal (5) Glutathione Peroxidase (1) Histone Acetyltransferase (3) Influenza Virus (1) Insulin Receptor (2) Isotope-Labeled Compounds (10) Lipase (1) Parasite (1) Phospholipase (1) PPAR (1) Reference Standards (8)
By Research Areas:	Cancer (20) Cardiovascular Disease (3) Infection (17) Inflammation/Immunology (5) Metabolic Disease (179) Neurological Disease (11)
Oligonucleotides:	Cationic Lipids (2)

351

Inhibitors & Agonists

Fluorescent Dyes

Biochemical Assay Reagents

Peptides

Natural
Products

Isotope-Labeled Compounds

Oligonucleotides

GMP Molecules

Targets Recommended: Free Fatty Acid Receptor Fatty Acid Synthase (FASN) FATP FABP FAAH ELOVL

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-128851

Coenzyme A 2 Publications Verification	Endogenous Metabolite Fatty Acid Synthase (FASN)	Metabolic Disease Cancer
Coenzyme A (CoASH) is a ubiquitous and essential cofactor, which is an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. Coenzyme A plays a central role in the oxidation of pyruvate in the citric acid cycle and the metabolism of carboxylic acids, including short- and long-chain fatty acids .

HY-128851B

Coenzyme A sodium 2 Publications Verification	Endogenous Metabolite Fatty Acid Synthase (FASN)	Metabolic Disease Cancer
Coenzyme A (CoASH) sodium is a ubiquitous and essential cofactor, which is an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. Coenzyme A plays a central role in the oxidation of pyruvate in the citric acid cycle and the metabolism of carboxylic acids, including short- and long-chain fatty acids .

HY-E70009

Acyl-CoA oxidase ACO	Glutathione Peroxidase	Others
Acyl-CoA oxidase (ACO) is a peroxisomal catalyst. Acyl-CoA oxidase acts as a key rate-limiting enzyme in the process of peroxisomal fatty acid β-oxidation. Acyl-CoA oxidase participates in lipid catabolism and phytohormone biosynthesis pathways .

HY-P2832

Acyl coenzyme A synthetase ACS	Endogenous Metabolite	Metabolic Disease Cancer
Acyl coenzyme A synthetase (ACS), namely acetyl coenzyme A synthetase, is often used in biochemical research. Acyl coenzyme A synthetase can catalyze the activation of fatty acids by coenzyme A through a two-step thioesterification reaction to produce acyl coenzyme A, and then participate in a variety of anabolic and catabolic lipid metabolism pathways, and participate in the TCA cycle in aerobic respiration .

HY-128851A

Coenzyme A trilithium 2 Publications Verification	Endogenous Metabolite Fatty Acid Synthase (FASN)	Metabolic Disease Cancer
Coenzyme A (CoASH) is a ubiquitous and essential cofactor, which is an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. Coenzyme A plays a central role in the oxidation of pyruvate in the citric acid cycle and the metabolism of carboxylic acids, including short- and long-chain fatty acids .

HY-D1570

BODIPY FL C12	Fluorescent Dye	Others
BODIPYFL C12 is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells . Maximum excitation/emission wavelength: 480/508 nm .

HY-113367

Suberylglycine	Endogenous Metabolite	Metabolic Disease
Suberylglycine is an acyl glycine, which is a normally minor metabolite of fatty acid.

HY-107396

YM-750	Acyltransferase	Cardiovascular Disease
YM-750 is a potent acyl-CoA:cholesterol acyltransferase (ACAT) inhibitor (IC₅₀=0.18 μM). ACAT catalyzes the formation of cholesteryl esters from cholesterol and long-chain fatty-acyl-coenzyme A .

HY-128851R

Coenzyme A (Standard)	Reference Standards Fatty Acid Synthase (FASN) Endogenous Metabolite	Metabolic Disease Cancer
Coenzyme A (Standard) is the analytical standard of Coenzyme A. This product is intended for research and analytical applications. Coenzyme A (CoASH) is a ubiquitous and essential cofactor, which is an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. Coenzyme A plays a central role in the oxidation of pyruvate in the citric acid cycle and the metabolism of carboxylic acids, including short- and long-chain fatty acids[1].

HY-113873

10-Thiastearic acid	Biochemical Assay Reagents	Metabolic Disease
10-Thiastearic acid inhibits desaturation of stearate to oleate. 10-Thiastearic acid has hypolipidemic effect .

HY-134438

Hexanoyl coenzyme A trilithium	Endogenous Metabolite	Metabolic Disease
Hexanoyl coenzyme A trilithium is a hexanoyl-based medium-chain fatty acyl coenzyme A that is present in all organisms. Hexanoyl coenzyme A trilithium can be used as a precursor for cannabinoid biosynthesis and acts as a competitive inhibitor of medium-chain acyl coenzyme A dehydrogenase (MCAD) .

HY-134428

Arachidonoyl coenzyme A lithium	Endogenous Metabolite	Metabolic Disease
Arachidonoyl coenzyme A lithium is an unsaturated fatty acyl coenzyme A, formed by the condensation of the thiol group of coenzyme A with the carboxyl group of arachidonic acid .

HY-CE00556

2-Hydroxypalmitoyl-CoA 2-Hydroxypalmitoyl-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
2-Hydroxypalmitoyl-CoA (2-Hydroxypalmitoyl-coenzyme A) is a hydroxy fatty-acyl-CoA.

HY-E70271

γ-Linolenoyl-CoA 6Z,9Z,12Z-Octadecatrienoyl-coenzyme A; γ-Linolenoylcoenzyme A; 6Z,9Z,12Z-Octadecatrienoyl-CoA	Endogenous Metabolite	Metabolic Disease
γ-Linolenoyl-CoA (C18:3(n6)-CoA) is a fatty acyl-CoA that can be used for lipidomics analysis of fatty acid-coenzyme A (FA-CoA) through LCMS/MS .

HY-130405

PtdIns-(1,2-dipalmitoyl) ammonium	Drug Derivative	Metabolic Disease
PtdIns-(1,2-dipalmitoyl) ammonium (DPPI) is a derivative of phosphatidylinositol (PtdIns) that contains C16:0 fatty acyl chains .

HY-CE01051

3-Ketostearoyl-CoA 3-Ketostearoyl-Coenzyme A	Biochemical Assay Reagents	Metabolic Disease
3-Ketostearoyl-CoA (3-Ketostearoyl-Coenzyme A) is a 3-oxo-fatty acyl-CoA .

HY-CE00435

(R)-3-Hydroxydecanoyl-CoA (R)-3-Hydroxydecanoyl-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
(R)-3-Hydroxydecanoyl-CoA ((R)-3-Hydroxydecanoyl-coenzyme A) is a 3-hydroxy fatty acyl-CoA.

HY-111199

JP83	FAAH	Neurological Disease
JP83 is an irreversible fatty acyl amide hydrolase (FAAH) inhibitor with an IC₅₀ of 1.6 nM in competitive activity-based protein profiling (ABPP) experiments .

HY-148869A

Hexanoyl-coenzyme A triammonium 06:0 Coenzyme A triammonium	Biochemical Assay Reagents	Metabolic Disease
Hexanoyl-Coenzyme A triammonium (06:0 Coenzyme A) is a medium-chain fatty acyl CoA that is an acyl donor substrate for ghrelin O-acyltransferase (GOAT) .

HY-CE00652

2-Hydroxyhexanoyl-CoA 2-Hydroxyhexanoyl-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
2-Hydroxyhexanoyl-CoA (2-Hydroxyhexanoyl-coenzyme A) is a hydroxy fatty acyl-CoA.

HY-CE00601

2-Hydroxyarachidoyl-CoA 2-Hydroxyarachidoyl-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
2-Hydroxyarachidoyl-CoA (2-Hydroxyarachidoyl-coenzyme A) is a hydroxy fatty-acyl-CoA.

HY-CE00618

2-Hydroxycerotoyl-CoA 2-Hydroxycerotoyl-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
2-Hydroxycerotoyl-CoA (2-Hydroxycerotoyl-coenzyme A) is a hydroxy fatty-acyl-CoA.

HY-CE00915

15-Hydroxypentadecanoyl-CoA 15-Hydroxypentadecanoyl-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
15-Hydroxypentadecanoyl-CoA (15-Hydroxypentadecanoyl-coenzyme A) is a hydroxy fatty acyl-CoA.

HY-CE00604

2-Hydroxybutanoyl-CoA 2-Hydroxybutanoyl-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
2-Hydroxybutanoyl-CoA (2-Hydroxybutanoyl-coenzyme A) is a hydroxy fatty acyl-CoA.

HY-CE00613

2-Hydroxycapryloyl-CoA 2-Hydroxyoctanoyl-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
2-Hydroxycapryloyl-CoA (2-Hydroxyoctanoyl-coenzyme A) is a hydroxy fatty-acyl-CoA.

HY-162298

γ-Linolenoyl monoethanolamide	Cannabinoid Receptor	Metabolic Disease
γ-Linolenoyl monoethanolamide, a kind of fatty N-acyl ethanolamine, is an endocannabinoid .

HY-CE00729

12-Hydroxyoctadecanoyl-CoA 12-Hydroxyoctadecanoyl-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
12-Hydroxyoctadecanoyl-CoA (12-Hydroxyoctadecanoyl-coenzyme A) is a hydroxy fatty acyl-CoA.

HY-CE01040

3-Hydroxyisoheptadecanoyl-CoA 3-Hydroxyisoheptadecanoyl-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
3-Hydroxyisoheptadecanoyl-CoA (3-Hydroxyisoheptadecanoyl-coenzyme A) is a methyl-branched fatty acyl-CoA.

HY-CE01041

3-Hydroxyisopentadecanoyl-CoA 3-Hydroxyisopentadecanoyl-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
3-Hydroxyisopentadecanoyl-CoA (3-Hydroxyisopentadecanoyl-coenzyme A) is a methyl-branched fatty acyl-CoA.

HY-CE00916

15-Keto-ETE-CoA 15-Keto-ETE-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
15-Keto-ETE-CoA (15-Keto-ETE-coenzyme A) is an oxo-fatty acyl-CoA.

HY-CE01037

3-Hydroxyhexacosanoyl-CoA 3-Hydroxyhexacosanoyl-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
3-Hydroxyhexacosanoyl-CoA (3-Hydroxyhexacosanoyl-coenzyme A) is a 3-hydroxy fatty acyl-CoA.

HY-CE01045

3-Hydroxytetracosanoyl-CoA 3-Hydroxytetracosanoyl-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
3-Hydroxytetracosanoyl-CoA (3-Hydroxytetracosanoyl-coenzyme A) is a very long-chain fatty acyl-CoA.

HY-CE00561

18-Hydroxyoleoyl-CoA 18-Hydroxyoleoyl-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
18-Hydroxyoleoyl-CoA (18-Hydroxyoleoyl-coenzyme A) is an omega-hydroxy fatty acyl-CoA.

HY-CE00452

(9Z)-Pentadecenoyl-CoA (9Z)-Pentadecenoyl-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
(9Z)-Pentadecenoyl-CoA ((9Z)-Pentadecenoyl-coenzyme A) is an unsaturated fatty acyl-CoA.

HY-CE00120

(3E)-tetradecenoyl-CoA (3E)-tetradecenoyl-coenzyme A	Biochemical Assay Reagents	Others
(3E)-tetradecenoyl-CoA ((3E)-tetradecenoyl-coenzyme A) is an unsaturated fatty acyl-CoA.

HY-CE01316

4-Methylpentanoyl-CoA 4-Methylpentanoyl-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
4-Methylpentanoyl-CoA (4-Methylpentanoyl-coenzyme A) is a methyl-branched fatty acyl-CoA .

HY-CE00361

(E,E)-Piperonyl-CoA (E,E)-Piperonyl-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
(E,E)-Piperonyl-CoA ((E,E)-Piperonyl-coenzyme A) is an unsaturated fatty acyl-CoA and a member of benzodioxoles.

HY-CE00710

2,6-Dimethylheptanoyl-CoA 2,6-Dimethylheptanoyl-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
2,6-Dimethylheptanoyl-CoA (2,6-Dimethylheptanoyl-coenzyme A) is a medium-chain fatty acyl-CoA.

HY-CE01047

3-Hydroxytetradecanoyl-CoA 3-Hydroxytetradecanoyl-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
3-Hydroxytetradecanoyl-CoA (3-Hydroxytetradecanoyl-coenzyme A) is a 3-hydroxy fatty acyl-CoA .

HY-CE00115

(2E)-Pentenoyl-CoA Pent-2-enoyl-coenzyme A	Biochemical Assay Reagents	Others
(2E)-Pentenoyl-CoA (Pent-2-enoyl-coenzyme A) is a monounsaturated fatty acyl-CoA.

HY-CE00390

(R)-2-Hydroxybutanoyl-CoA (R)-2-Hydroxybutanoyl-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
(R)-2-Hydroxybutanoyl-CoA ((R)-2-Hydroxybutanoyl-coenzyme A) is a hydroxy fatty acyl-CoA.

HY-E70246

Nonanoyl-CoA Pelargonoyl-CoA; S-Nonanoate coenzyme A; Nonanoyl-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
Nonanoyl-CoA (Pelargonoyl-CoA) is a medium-chain fatty acyl-CoA that can be used as substrate for the medium-chain hydrolase .

HY-CE00657

2-Hydroxyisovaleryl-CoA 2-Hydroxy-3-methylbutanoyl-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
2-Hydroxyisovaleryl-CoA (2-Hydroxy-3-methylbutanoyl-coenzyme A) is a hydroxy fatty-acyl-CoA.

HY-CE00702

3,5,7-Trioxododecanoyl-CoA 3,5,7-Trioxododecanoyl-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
3,5,7-Trioxododecanoyl-CoA (3,5,7-Trioxododecanoyl-coenzyme A) is an oxo fatty acyl-CoA.

HY-CE00273

(R)-Carnitinyl-CoA betaine (R)-Carnitinyl-coenzyme A betaine	Biochemical Assay Reagents	Metabolic Disease
(R)-Carnitinyl-CoA betaine ((R)-Carnitinyl-coenzyme A betaine) is an ammonium betaine and a 3-hydroxy fatty acyl-CoA.

HY-CE00644

11-Keto-ETE-CoA 11-Keto-ETE-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
11-Keto-ETE-CoA (11-Keto-ETE-coenzyme A) is a 3-oxo-fatty acyl-CoA.

HY-113367S

Suberylglycine-d4	Endogenous Metabolite	Metabolic Disease
Suberylglycine-d₄ is the deuterium labeled Suberylglycine. Suberylglycine is an acyl glycine, which is a normally minor metabolite of fatty acid .

HY-E70247

(S)-3-Hydroxyhexanoyl-CoA L-3-Hydroxyhexanoyl-CoA	Endogenous Metabolite	Others
(S)-3-Hydroxyhexanoyl-CoA (L-3-Hydroxyhexanoyl-CoA) is a hydroxy fatty acyl-CoA .

HY-CE00457

(Z)-Hex-3-enoyl-CoA (Z)-Hex-3-enoyl-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
(Z)-Hex-3-enoyl-CoA ((Z)-Hex-3-enoyl-coenzyme A) is a fatty acyl-CoA.

HY-CE00410

(S)-3-Hydroxypentanoyl-CoA (3S)-Hydroxyvaleryl-coenzyme A	Biochemical Assay Reagents	Metabolic Disease
(S)-3-Hydroxypentanoyl-CoA ((3S)-Hydroxyvaleryl-coenzyme A) is a 3-hydroxy fatty acyl-CoA.

Cat. No.	Product Name	Type

HY-D1570

BODIPY FL C12

Fluorescent Dyes

BODIPYFL C12 is a BODIPY dye. BODIPY dye is a small molecule dye with strong ultraviolet absorption ability, its fluorescence peak is relatively sharp, and the quantum yield is high. They are relatively insensitive to the polarity and pH of the environment and are relatively stable under different physiological conditions. Due to its structural asymmetry, BODIPY derives a variety of structural products. BODIPY lipid droplet dyes can well pass through the cell membrane into the cell, and localize the neutral lipids in the cell to specifically stain the lipid droplets, which can be used for labeling of live cells and fixed cells . Maximum excitation/emission wavelength: 480/508 nm .

HY-B0399G

L-Carnitine

(R)-Carnitine; Levocarnitine

Fluorescent Dyes

L-Carnitine (GMP) is L-Carnitine (HY-B0399) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. L-Carnitine, a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine is an antioxidant. L-Carnitine can ameliorate metabolic imbalances in many inborn errors of metabolism .

Cat. No.	Product Name	Type

HY-128851B

Coenzyme A sodium 2 Publications Verification	Biochemical Assay Reagents
Coenzyme A (CoASH) sodium is a ubiquitous and essential cofactor, which is an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. Coenzyme A plays a central role in the oxidation of pyruvate in the citric acid cycle and the metabolism of carboxylic acids, including short- and long-chain fatty acids .

HY-128851A

Coenzyme A trilithium 2 Publications Verification	Biochemical Assay Reagents
Coenzyme A (CoASH) is a ubiquitous and essential cofactor, which is an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. Coenzyme A plays a central role in the oxidation of pyruvate in the citric acid cycle and the metabolism of carboxylic acids, including short- and long-chain fatty acids .

HY-W105518

L-Carnitine tartrate

Maximum Cited Publications

20 Publications Verification

Biochemical Assay Reagents

L-Carnitine tartrate is a highly polar, small zwitterion. L-Carnitine tartrate is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine tartrate functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine tartrate is an antioxidant. L-Carnitine tartrate can ameliorate metabolic imbalances in many inborn errors of metabolism ^{[3] ^.}

HY-134438

Hexanoyl coenzyme A trilithium	Biochemical Assay Reagents
Hexanoyl coenzyme A trilithium is a hexanoyl-based medium-chain fatty acyl coenzyme A that is present in all organisms. Hexanoyl coenzyme A trilithium can be used as a precursor for cannabinoid biosynthesis and acts as a competitive inhibitor of medium-chain acyl coenzyme A dehydrogenase (MCAD) .

HY-134428

Arachidonoyl coenzyme A lithium	Biochemical Assay Reagents
Arachidonoyl coenzyme A lithium is an unsaturated fatty acyl coenzyme A, formed by the condensation of the thiol group of coenzyme A with the carboxyl group of arachidonic acid .

HY-W127393

N-Nonanoyl-L-homoserine lactone

Biochemical Assay Reagents

Quorum sensing is a regulatory system used by bacteria to control gene expression in response to increased cell density. This regulatory process manifests itself in a variety of phenotypes, including biofilm formation and virulence factor production. Coordinated gene expression is achieved through the production, release and detection of small diffusible signaling molecules called autoinducers. N-acylated homoserine lactones (AHLs) comprise a class of such autoinducers, each of which generally consists of a fatty acid coupled to a homoserine lactone (HSL). Modulation of bacterial quorum-sensing signaling systems to suppress pathogenesis represents a new approach to antimicrobial research for infectious diseases. AHLs differ in acyl length (C4-C18), C3 substitution (hydrogen, hydroxyl, or oxo group), and the presence or absence of one or more carbon-carbon double bonds in the fatty acid chain. These differences confer signaling specificity through the affinity of the LuxR family of transcriptional regulators. C9-HSL is a rare odd-numbered acyl carbon chain produced by wild-type Erwinia carotovora strain SCC 3193 grown in nutrient-rich Luria-Bertani broth (LB) medium.

HY-134136

Octanoyl Coenzyme A	Biochemical Assay Reagents
Octanoyl coenzyme A is an enoyl-CoA hydratase binder. Octanoyl coenzyme A binds to the active site of enoyl-CoA hydratase, occupies the binding pocket for the fatty acid tail of the enzyme's substrate, and induces a conformational shift in a flexible protein loop via its longer octanoyl chain, forming an open channel leading to the inter-trimer gap .

HY-W127461

Ganglioside GM2, Asialo

Gangliotriosylceramide

Biochemical Assay Reagents

Ganglioside GM2 asialo (asialo-GM2) is a glycosphingolipid containing three monosaccharide residues and one fatty acid of variable chain length, but lacks the sialic acid residue present on ganglioside M2. Asialo-GM2 is found at low or undetectable levels in normal human brains, but it accumulates in the brains of patients with Tay-Sachs disease and Sandhoff disease, which are expressed as lysosomal β- A neurodegenerative disorder characterized by hexosaminidase A and B deficiency. It also binds to various bacteria, including Pseudomonas isolated from cystic fibrosis patients. The Asialo-GM2 mixture contains ganglioside GM2 asialo molecular species with fatty acyl chains of variable length.

HY-114773

N-Undecanoyl-L-homoserine lactone

Biochemical Assay Reagents

Quorum sensing is a regulatory system used by bacteria to control gene expression in response to increased cell density. This regulatory process manifests itself in a variety of phenotypes, including biofilm formation and virulence factor production. Coordinated gene expression is achieved through the production, release and detection of small diffusible signaling molecules called autoinducers. N-acylated homoserine lactones (AHLs) comprise a class of such autoinducers, each of which generally consists of a fatty acid coupled to a homoserine lactone (HSL). Modulation of bacterial quorum-sensing signaling systems to suppress pathogenesis represents a new approach to antimicrobial research for infectious diseases. AHLs differ in acyl length (C4-C18), C3 substitution (hydrogen, hydroxyl, or oxo group), and the presence or absence of one or more carbon-carbon double bonds in the fatty acid chain. These differences confer signaling specificity through the affinity of the LuxR family of transcriptional regulators. C11-HSL has a rare odd-numbered acyl carbon chain and may be a minor quorum-sensing signaling molecule in Pseudomonas aeruginosa strains.

HY-B0399G

L-Carnitine

(R)-Carnitine; Levocarnitine

Biochemical Assay Reagents

HY-W105518R

L-Carnitine tartrate (Standard)

Biochemical Assay Reagents

L-Carnitine (tartrate) (Standard) is the analytical standard of L-Carnitine (tartrate). This product is intended for research and analytical applications. L-Carnitine tartrate is a highly polar, small zwitterion. L-Carnitine tartrate is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine tartrate functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine tartrate is an antioxidant. L-Carnitine tartrate can ameliorate metabolic imbalances in many inborn errors of metabolism ^{[3] ^.}

HY-W127487

N-Octadecanoyl-L-homoserine lactone

Biochemical Assay Reagents

Quorum sensing is a regulatory system used by bacteria to control gene expression in response to increased cell density. This regulatory process manifests itself in a variety of phenotypes, including biofilm formation and virulence factor production. Coordinated gene expression is achieved through the production, release and detection of small diffusible signaling molecules called autoinducers. N-acylated homoserine lactones (AHLs) comprise a class of such autoinducers, each of which generally consists of a fatty acid coupled to a homoserine lactone (HSL). Modulation of bacterial quorum-sensing signaling systems to suppress pathogenesis represents a new approach to antimicrobial research for infectious diseases. AHLs differ in acyl length (C4-C18), C3 substitution (hydrogen, hydroxyl, or oxo group), and the presence or absence of one or more carbon-carbon double bonds in the fatty acid chain. These differences confer signaling specificity through the affinity of the LuxR family of transcriptional regulators. C18-HSL, one of four lipophilic long acyl side chain AHLs produced by the LuxI AHL synthase homolog SinI, is involved in quorum-sensing signaling in strains of Rhizobium meliloti (a nitrogen-fixing bacterial symbiont of the legume M. sativa) . C18-HSL and other hydrophobic AHLs tend to localize in the relatively lipophilic environment of bacterial cells and cannot diffuse freely across the cell membrane. Long-chain N-acyl homoserine lactones can be exported from cells by efflux pumps, or can be transported between communicating cells by extracellular outer membrane vesicles.

Cat. No.	Product Name	Target	Research Area

HY-P1743

Acyl Carrier Protein (ACP) (65-74)	Peptides	Infection
Acyl Carrier Protein (ACP) (65-74) is a key coenzyme fragment of fatty acid synthase (FAS) and participates in fatty acid synthesis as an acyl carrier. Acyl Carrier Protein (ACP) (65-74) mediates condensation, reduction and other cyclic reactions in fatty acid synthesis by covalently binding to acyl chains to form acyl-ACP intermediates, promoting acyl chain extension. Acyl Carrier Protein (ACP) (65-74) can regulate the synthesis ratio of saturated and unsaturated fatty acids. Acyl Carrier Protein (ACP) (65-74) can be used to study the mechanism of bacterial fatty acid synthesis and is a potential target for antibiotics (such as inhibiting the FAS system of pathogens) .

HY-124081

N-Oleoyl-L-serine	Apoptosis	Metabolic Disease
N-Oleoyl-L-Serine is an endogenous amide of long-chain fatty acids with ethanolamine (N-acyl amides). N-Oleoyl-L-Serine is a lipid regulator of bone remodeling and stimulates osteoclast apoptosis. N-Oleoyl-L-Serine can be used for antiosteoporotic drug discovery development .

HY-P11321A

IUB0271 hydrochloride acyl-GIP hydrochloride	Insulin Receptor	Metabolic Disease
IUB0271 (acyl-GIP) hydrochloride is a fatty acylated and long-acting glucose-dependent insulinotropic polypeptide (GIP). IUB0271 hydrochloride increases cFos neuronal activity in hypothalamic feeding centers and decreases body weight, food intake and glycemia in DIO mouse models, and these effects depend on CNS-GIPR signaling. IUB0271 hydrochloride can be used for type 2 diabetes mellitus (T2DM) and obesity research .

HY-P11321

IUB0271 acyl-GIP	Insulin Receptor	Metabolic Disease
IUB0271 (acyl-GIP) is a fatty acylated and long-acting glucose-dependent insulinotropic polypeptide (GIP). IUB0271 increases cFos neuronal activity in hypothalamic feeding centers and decreases body weight, food intake and glycemia in DIO mouse models, and these effects depend on CNS-GIPR signaling. IUB0271 can be used for type 2 diabetes mellitus (T2DM) and obesity research .

Cat. No.	Product Name	Category	Target	Chemical Structure

HY-B0399

L-Carnitine Maximum Cited Publications 20 Publications Verification (R)-Carnitine; Levocarnitine	Natural Products Human Gut Microbiota Metabolites Immune System Disorder Microorganisms Neurological Disease Disease markers Endocrine diseases Nervous System Disorder Endogenous metabolite Disease Research Fields Cancer Source Classification	Endogenous Metabolite
L-Carnitine ((R)-Carnitine), a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine is an antioxidant. L-Carnitine can ameliorate metabolic imbalances in many inborn errors of metabolism .

HY-128851

Coenzyme A 2 Publications Verification	Natural Products Human Gut Microbiota Metabolites Microorganisms Endogenous metabolite Source Classification	Endogenous Metabolite Fatty Acid Synthase (FASN)
Coenzyme A (CoASH) is a ubiquitous and essential cofactor, which is an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. Coenzyme A plays a central role in the oxidation of pyruvate in the citric acid cycle and the metabolism of carboxylic acids, including short- and long-chain fatty acids .

HY-113166

Dodecanoylcarnitine 1 Publications Verification (-)-Lauroylcarnitine	Structural Classification Immune System Disorder Classification of Application Fields Ketones, Aldehydes, Acids Disease markers Endocrine diseases Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Dodecanoylcarnitine ((-)-Lauroylcarnitine) is a medium long-chain acylcarnitine, an intermediate product in key energy metabolic pathways of fatty acid β-oxidation and amino acids catabolism. The abnormal decrease in the Dodecanoylcarnitine levels indicats that mitochondrial fuel metabolism, including fatty acid oxidation is significantly disturbed. Changes in plasma concentrations of Dodecanoylcarnitine are not only associated with type II diabetes, but also with pre-diabetes status. Dodecanoylcarnitine is present in fatty acid oxidation disorders such as long-chain acyl CoA dehydrogenase deficiency, carnitine palmitoyltransferase I/II deficiency, and is also associated with celiac disease. Dodecanoylcarnitine deomonstrates high sensitivities and specificities in predicting asthma. Combined model of Decanoylcarnitine (HY-113069), Dodecanoylcarnitine, PC (16:0/0:0), and Asp Arg Pro can be used as a potential biomarker for the diagnosis of Yin-deficiency-heat syndrome .

HY-B2246

L-Carnitine hydrochloride Maximum Cited Publications 20 Publications Verification (R)-Carnitine hydrochloride; Levocarnitine hydrochloride	Classification of Application Fields Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
L-Carnitine hydrochloride ((R)-Carnitine hydrochloride), a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine hydrochloride functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine hydrochloride is an antioxidant. L-Carnitine hydrochloride can ameliorate metabolic imbalances in many inborn errors of metabolism .

HY-113201

Tetradecanoylcarnitine	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Disease markers Endocrine diseases Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Tetradecanoylcarnitine is an acylcarnitine involved in mitochondrial β-oxidation of long-chain saturated fatty acids and fatty acid metabolism. Tetradecanoylcarnitine serves as a biomarker for *very long-chain acyl-CoA dehydrogenase* deficiency and MPTP (HY-15608)-induced Parkinson's disease. Tetradecanoylcarnitine exhibits a characteristic significant elevation in plasma levels in patients with sarcopenia, including those complicated with hypertension, and this elevation is closely associated with an increased risk of death. Tetradecanoylcarnitine is widely used in research on the pathological mechanisms of diseases such as Parkinson's disease and sarcopenia .

HY-141466

Crotonyl-CoA	Structural Classification Natural Products Classification of Application Fields Metabolic Disease Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite Histone Acetyltransferase
Crotonyl-CoA, a high-energy acyl donor, is an intermediate in the fermentation of butyric acid, and in the metabolism of lysine and tryptophan. Crotonyl-CoA is important in the metabolism of fatty acids and amino acids. Crotonyl-CoA acts as a substrate for p300’s histone crotonyltransferase activity, competing with acetyl-CoA for p300-mediated histone acylation reactions. Crotonyl-CoA regulates global and gene-specific histone crotonylation levels in cells, with cellular concentration changes altering histone crotonylation at regulatory elements of activated genes. Crotonyl-CoA serves as the substrate for crotonyl-CoA reductase/carboxylase (CCRC)-catalyzed NADPH-mediated reduction and carbon dioxide trapping to form unusual alkylmalonyl-CoA polyketide synthase extender units. Crotonyl-CoA can be used for the research of LPS-induced inflammatory response .

HY-W015580

(+)-Fenchone	Structural Classification Classification of Application Fields Ketones, Aldehydes, Acids Other Diseases Umbelliferae Plants Vernonia Schreb. Disease Research Fields Source Classification	Bacterial Fungal
(+)-Fenchone is an antibacterial agent. (+)-Fenchone interferes with bacterial fatty acid synthesis, disrupts fungal cell wall construction, and inhibits bacterial biofilm formation. (+)-Fenchone can be used in studies related to bacterial and fungal infections .

HY-113367

Suberylglycine	Classification of Application Fields Ketones, Aldehydes, Acids Disease markers Metabolic Disease Endocrine diseases Endogenous metabolite Disease Research Fields Source Classification	Endogenous Metabolite
Suberylglycine is an acyl glycine, which is a normally minor metabolite of fatty acid.

HY-B0399R

L-Carnitine (Standard) (R)-Carnitine (Standard); Levocarnitine (Standard)	Structural Classification Natural Products Human Gut Microbiota Metabolites Immune System Disorder Microorganisms Disease markers Endocrine diseases Nervous System Disorder Endogenous metabolite Cancer Source Classification	Reference Standards Endogenous Metabolite
L-Carnitine (Standard) is the analytical standard of L-Carnitine. This product is intended for research and analytical applications. L-Carnitine ((R)-Carnitine), a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine is an antioxidant. L-Carnitine can ameliorate metabolic imbalances in many inborn errors of metabolism .

HY-128851R

Coenzyme A (Standard)	Structural Classification Natural Products Human Gut Microbiota Metabolites Microorganisms Endogenous metabolite Source Classification	Reference Standards Fatty Acid Synthase (FASN) Endogenous Metabolite
Coenzyme A (Standard) is the analytical standard of Coenzyme A. This product is intended for research and analytical applications. Coenzyme A (CoASH) is a ubiquitous and essential cofactor, which is an acyl group carrier and carbonyl-activating group for the citric acid cycle and fatty acid metabolism. Coenzyme A plays a central role in the oxidation of pyruvate in the citric acid cycle and the metabolism of carboxylic acids, including short- and long-chain fatty acids[1].

HY-113367R

Suberylglycine (Standard)	Structural Classification Ketones, Aldehydes, Acids Disease markers Endocrine diseases Endogenous metabolite Source Classification	Endogenous Metabolite Reference Standards
Suberylglycine (Standard) is the analytical standard of Suberylglycine. This product is intended for research and analytical applications. Suberylglycine is an acyl glycine, which is a normally minor metabolite of fatty acid.

HY-136821

Polymyxin D2	Microorganisms Antibiotics Other Antibiotics Source Classification	Bacterial Antibiotic
Polymyxin D2 is an antibiotic discovered from Bacillus polymyxa, exhibiting antibacterial activity. Its core structure consists of a cyclic heptapeptide moiety and a tripeptide side chain with a fatty acyl residue. Polymyxin D2 can be used in anti-infective research .

HY-B2246R

L-Carnitine hydrochloride (Standard) (R)-Carnitine hydrochloride (Standard); Levocarnitine hydrochloride (Standard)	Structural Classification Ketones, Aldehydes, Acids Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
L-Carnitine (hydrochloride) (Standard) is the analytical standard of L-Carnitine (hydrochloride). This product is intended for research and analytical applications. L-Carnitine hydrochloride ((R)-Carnitine hydrochloride), a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine hydrochloride functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine hydrochloride is an antioxidant. L-Carnitine hydrochloride can ameliorate metabolic imbalances in many inborn errors of metabolism .

HY-113166R

Dodecanoylcarnitine (Standard) (-)-Lauroylcarnitine (Standard)	Structural Classification Immune System Disorder Microorganisms Ketones, Aldehydes, Acids Disease markers Endocrine diseases Endogenous metabolite Source Classification	Reference Standards Endogenous Metabolite
Dodecanoylcarnitine (Standard) is the analytical standard of Dodecanoylcarnitine (HY-113166). This product is intended for research and analytical applications. Dodecanoylcarnitine ((-)-Lauroylcarnitine) is a medium long-chain acylcarnitine, an intermediate product in key energy metabolic pathways of fatty acid β-oxidation and amino acids catabolism. The abnormal decrease in the Dodecanoylcarnitine levels indicats that mitochondrial fuel metabolism, including fatty acid oxidation is significantly disturbed. Changes in plasma concentrations of Dodecanoylcarnitine are not only associated with type II diabetes, but also with pre-diabetes status. Dodecanoylcarnitine is present in fatty acid oxidation disorders such as long-chain acyl CoA dehydrogenase deficiency, carnitine palmitoyltransferase I/II deficiency, and is also associated with celiac disease. Dodecanoylcarnitine deomonstrates high sensitivities and specificities in predicting asthma. Combined model of Decanoylcarnitine (HY-113069), Dodecanoylcarnitine, PC (16:0/0:0), and Asp Arg Pro can be used as a potential biomarker for the diagnosis of Yin-deficiency-heat syndrome .

HY-N15804

28:0 Coenzyme A ammonium	Lipid	Biochemical Assay Reagents
28:0 Coenzyme A ammonium is an acyl coA-saturated fatty acid.

HY-N17702

CerPCho (d18:0/22:0)	Structural Classification Endogenous metabolite Lipid Source Classification	Endogenous Metabolite
CerPCho (d18:0/22:0) is a sphingomyelin with a d18:0-type sphingosine long-chain base and a 22:0-type N-acyl fatty acid .

Cat. No.	Product Name	Chemical Structure

HY-B0399S

L-Carnitine-d9

1 Publications Verification

L-Carnitine-d₉ is the deuterium labeled L-Carnitine. L-Carnitine (Levocarnitine) is an endogenous molecule involved in fatty acid metabolism, biosynthesized within the human body using amino acids: L-lysine and L-methionine, as substrates. L-Carnitine functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-carnitine can ameliorate metabolic imbalances in many inborn errors of metabolism .

HY-B2246S

L-Carnitine-d9 chloride

1 Publications Verification

L-Carnitine-d₉ (chloride)e is the deuterium labeled L-Carnitine chloride. L-Carnitine chloride, a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine chloride functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine chloride is an antioxidant. L-Carnitine chloride can ameliorate metabolic imbalances in many inborn errors of metabolism .

HY-W747491

Triclosan-13C12

Triclosan- ¹³C₁₂ is ¹³C labeled Triclosan (HY-B1119). Triclosan is a broad-spectrum antibacterial agent that inhibits bacterial fatty acid synthesis at the enoyl-acyl carrier protein reductase (FabI) step. Triclosan inhibits E. coli enoyl-acyl carrier protein reductase (FabI) and FabI containing a glycine-to-valine substitution at position 93 (FabIG93V) with IC₅₀s of 2 μM and 10 μM, respectively. Triclosan causes apoptotic effect in cultured rat neural stem cells (NSC). Triclosan exacerbates colitis and colitis-associated colorectal tumorigenesis in animal models .

HY-W653962

Triclosan-13C6

Triclosan- ¹³C₆ is ¹³C labeled Triclosan. Triclosan is a broad-spectrum antibacterial agent that inhibits bacterial fatty acid synthesis at the enoyl-acyl carrier protein reductase (FabI) step. Triclosan inhibits E. coli enoyl-acyl carrier protein reductase (FabI) and FabI containing a glycine-to-valine substitution at position 93 (FabIG93V) with IC₅₀s of 2 μM and 10 μM, respectively. Triclosan causes apoptotic effect in cultured rat neural stem cells (NSC). Triclosan exacerbates colitis and colitis-associated colorectal tumorigenesis in animal models .

HY-B0399S2

L-Carnitine-13C3

L-Carnitine- ¹³C₃ ((R)-Carnitine- ¹³C₃) is the ¹³C--labeled L-Carnitine (HY-B0399). L-Carnitine ((R)-Carnitine), a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine is an antioxidant. L-Carnitine can ameliorate metabolic imbalances in many inborn errors of metabolism .

HY-113367S

Suberylglycine-d4
Suberylglycine-d₄ is the deuterium labeled Suberylglycine. Suberylglycine is an acyl glycine, which is a normally minor metabolite of fatty acid .

HY-113367S1

Suberylglycine-d2
Suberylglycine-d₂ is the deuterium labeled Suberylglycine. Suberylglycine is an acyl glycine, which is a normally minor metabolite of fatty acid .

HY-W769723

3-Hydroxyhippuric acid-13C2,15N
3-Hydroxyhippuric acid- ¹³C₂, ¹⁵N is the ¹³C- and ¹⁵N-labeled 3-Hydroxyhippuric acid (HY-113085). 3-Hydroxyhippuric acid is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids.

HY-W769171

Suberylglycine-13C2,15N
Suberylglycine- ¹³C₂, ¹⁵N is the ¹³C- and ¹⁵N-labeled Suberylglycine (HY-113367). Suberylglycine is an acyl glycine, which is a normally minor metabolite of fatty acid.

HY-W706234

Nonanoyl-CoA-d17
Nonanoyl-CoA-d₁₇ (Pelargonoyl-CoA-d₁₇) is the deuterium labeled Nonanoyl-CoA (HY-E70246). Nonanoyl-CoA is a medium-chain fatty acyl-CoA that can be used as substrate for the medium-chain hydrolase .

HY-W754236

(R)-Carnitine Hydrochloride-13C3

(R)-Carnitine Hydrochloride- ¹³C₃ is the ¹³C-labeled L-Carnitine hydrochloride (HY-B2246). L-Carnitine hydrochloride ((R)-Carnitine hydrochloride), a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine hydrochloride functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine hydrochloride is an antioxidant. L-Carnitine hydrochloride can ameliorate metabolic imbalances in many inborn errors of metabolism .

Cat. No.	Product Name		Classification

HY-113166

Dodecanoylcarnitine 1 Publications Verification (-)-Lauroylcarnitine		Cationic Lipids
Dodecanoylcarnitine ((-)-Lauroylcarnitine) is a medium long-chain acylcarnitine, an intermediate product in key energy metabolic pathways of fatty acid β-oxidation and amino acids catabolism. The abnormal decrease in the Dodecanoylcarnitine levels indicats that mitochondrial fuel metabolism, including fatty acid oxidation is significantly disturbed. Changes in plasma concentrations of Dodecanoylcarnitine are not only associated with type II diabetes, but also with pre-diabetes status. Dodecanoylcarnitine is present in fatty acid oxidation disorders such as long-chain acyl CoA dehydrogenase deficiency, carnitine palmitoyltransferase I/II deficiency, and is also associated with celiac disease. Dodecanoylcarnitine deomonstrates high sensitivities and specificities in predicting asthma. Combined model of Decanoylcarnitine (HY-113069), Dodecanoylcarnitine, PC (16:0/0:0), and Asp Arg Pro can be used as a potential biomarker for the diagnosis of Yin-deficiency-heat syndrome .

HY-169794

N-Palmitoyl-phenylalanine		Cationic Lipids
N-Palmitoyl-phenylalanine is an N-acyl amide that contains the long-chain saturated fatty acid Palmitic acid (HY-N0830) conjugated via an amide bond to the essential amino acid L-Phenylalanine (HY-N0215). N-Palmitoyl-phenylalanine inhibits pre-mRNA splicing in HeLa cell nuclear lysates (IC₅₀ ＞ 400 μM) but has no splicing activity in intact HeLa cells .

Targets Recommended: Free Fatty Acid Receptor Fatty Acid Synthase (FASN) FATP FABP FAAH ELOVL

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-B0399G

L-Carnitine (R)-Carnitine; Levocarnitine	Endogenous Metabolite	Neurological Disease Cancer
L-Carnitine (GMP) is L-Carnitine (HY-B0399) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. L-Carnitine, a highly polar, small zwitterion, is an essential co-factor for the mitochondrial β-oxidation pathway. L-Carnitine functions to transport long chain fatty acyl-CoAs into the mitochondria for degradation by β-oxidation. L-Carnitine is an antioxidant. L-Carnitine can ameliorate metabolic imbalances in many inborn errors of metabolism .

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