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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
60 Results for "
feces
" in MedChemExpress (MCE) Product Catalog:
Products (60)
60 Results for "feces" in MCE Product Catalog:
7
Gut restricted-7 (GR-7) is a potent, covalent and orally active pan-bile salt hydrolase (BSH) inhibitor. Gut restricted-7 has a tissue-selective and is restricted to the gut. Gut restricted-7 decreases gut bacterial BSHs and decreases deconjugated bile acid levels in feces of mice .
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6 Cited Publications
Cat. No.: HY-W007355
CAS No.: 83-34-1
Synonyms: 3-Methylindole; 3-Methyl-1H-indole
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Temephos (Temefos) is an orally active, blood-brain barrier-permeable organophosphate insecticide and AChE inhibitor. By irreversibly inhibiting AChE to induce cholinergic overactivation, Temephos effectively blocks larval development of Aedes aegypti (yellow fever mosquito) and Aedes albopictus (Asian tiger mosquito), and is commonly used in studies related to Dengue Virus, Zika Virus and other relevant pathogens. Temephos exhibits genotoxicity and neurodevelopmental toxicity, and may also cause liver injury, reproductive system abnormalities and cholinergic poisoning symptoms in mammals. Temephos tends to accumulate in adipose tissues and aquatic organisms, and is excreted via feces after metabolism through oxidation and hydrolysis. Note that CYP-mediated metabolic detoxification may reduce the actual larvicidal efficacy of Temephos against some mosquito species. Temephos can be used in research related to dengue fever, Zika virus disease, chikungunya and dracunculiasis .
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1 Cited Publications
Synonyms: 4-O-β-D-Galactopyranosyl-D-fructose
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1
Category:
Human Gut Microbiota Metabolites Ketones, Aldehydes, Acids Other Diseases Endogenous metabolite Disease Research Fields
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1
1 Cited Publications
Cat. No.: HY-W399297
CAS No.: 566-17-6
Synonyms: 7α,12α-Dihydroxycholanoic acid
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1 Cited Publications
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Apovincaminic acid hydrochloride salt is the major metabolite of Vinpocetine (HY-13295), with blood-brain barrier permeability and oral activity. Apovincaminic acid hydrochloride salt is detectable in the plasma of pregnant rabbits after oral administration of Vinpocetine. Apovincaminic acid hydrochloride salt is absorbable from all segments of the gastrointestinal tract of Norway rat, with the stomach as the primary absorption site, and is excreted via urine and feces. Apovincaminic acid hydrochloride salt is used in the research of cerebrovascular diseases .
Cat. No.: HY-W004305
CAS No.: 629-80-1
Synonyms: Palmitaldehyde
Category:
Human Gut Microbiota Metabolites Ketones, Aldehydes, Acids Metabolic Disease Endogenous metabolite Disease Research Fields
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Amprolium hydrochloride is a thiamine transporter inhibitor and antiparasitic agent with oral activity and blood-brain barrier penetration. Amprolium hydrochloride blocks thiamine transport at the blood-brain barrier and intestine, and competitively inhibits thiamine pyrophosphokinase, inducing thiamine pyrophosphate deficiency and impairing carbohydrate synthesis. Amprolium hydrochloride induces oxidative stress, alters antioxidant enzyme activity, and inhibits acetylcholinesterase (AchE) activity. Amprolium hydrochloride disrupts reproductive organs and gametogenesis, and causes histopathological and ultrastructural damage to multiple organs. Amprolium hydrochloride induces thiamine deficiency, reduces body weight gain in mice, and causes psychomotor behavioral changes and nephropathy. Amprolium hydrochloride exhibits molluscicidal activity against the terrestrial snail Eobania vermiculata, and reduces the shedding of Eimeria meleagrimitis oocysts in feces and litter. Amprolium hydrochloride can be used for research on thiamine deficiency and coccidiosis .
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MCC-DM1 is a agent-Linker Conjugates for ADC such as Anti-CD22-MCC-DM1. MCC-DM1 can be detected in rat and human plasma, feces, and other tissues .
Cat. No.: HY-W010435
CAS No.: 110-93-0
Synonyms: 6-Methyl-5-hepten-2-one
Cat. No.: HY-W010516
CAS No.: 97-61-0
Synonyms: 2-Methylpentanoic acid
Category:
Ketones, Aldehydes, Acids Metabolic Disease Plants Other Families Extract Endogenous metabolite Disease Research Fields
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Cat. No.: HY-165151
CAS No.: 28925-89-5
Synonyms: Urochrome hydrochloride
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Urobilin hydrochloride is the metabolite of Hemoglobin (HY-P2995), that can be excreted through urine and feces in many mammals. Urobilin hydrochloride can be used as an indicator of human waste pollution .
Cat. No.: HY-W585922
CAS No.: 3338-16-7
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3β-Cholic acid is a derivative of cholic acid (HY-N0324), and can be found in human feces .
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3-Oxochenodeoxycholic acid is an endogenous metabolite that can be found in feces. 3-Oxochenodeoxycholic acid can serve as an indicator for the diagnosis of certain diseases, such as COVID-19 .
Cat. No.: HY-W006449
CAS No.: 168828-90-8
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PNU-105368 is a metabolite of Linezolid (HY-10394) . PNU-105368 exists mainly in the form of the original form and two metabolites in the human body and is excreted through the kidneys and feces .
Cat. No.: HY-N3516
CAS No.: 392274-22-5
Category:
Stilbenes Moraceae Extract Metabolic Disease Phenols Polyphenols Plants Disease Research Fields Morus alba Linn.
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11(Z),14(Z)-Eicosadienoic acid is an unsaturated fatty acid that can serve as a biomarker for Alzheimer's disease. 11(Z),14(Z)-Eicosadienoic acid is downregulated in the feces and upregulated in the hippocampus of Alzheimer's disease model mice. 11(Z),14(Z)-Eicosadienoic acid can be used for research on Alzheimer's disease .
Cat. No.: HY-W007355R
CAS No.: 83-34-1
Synonyms: 3-Methylindole (Standard); 3-Methyl-1H-indole (Standard)
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
