4618-18-2
Chemical Structure
Lactulose
Synonym(s): 4-O-β-D-Galactopyranosyl-D-fructose
- CAS No.: 4618-18-2
- Formula:C12H22O11
- Molecular Weight:342.30
IUPAC Name: (3S,4R,5R)-1,3,5,6-tetrahydroxy-4-(((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)hexan-2-one
InChIKey: PFCRQPBOOFTZGQ-VZXVHDRGSA-N
SMILES: OCC([C@H]([C@@H]([C@@H](CO)O)O[C@H]1[C@@H]([C@H]([C@H]([C@@H](CO)O1)O)O)O)O)=O
Biological Activity: Lactulose is an orally active galactose-fructose disaccharide. Lactulose suppresses upregulation of TNF-α and IL-6. Lactulose decreases the degree of DNA damage. Lactulose exhibits many of the properties of other oligosaccharides, including increasing the numbers of Bifidobacteria in feces. Lactulose restores the structure and composition of the intestinal microbiota, mitigates inflammation, and suppresses inflammatory tumorigenesis in mice with colitis-associated cancer. Lactulose can be used in the research of constipation[1][2].
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Lactulose | 99.88% | Lactulose is an orally active galactose-fructose disaccharide. Lactulose suppresses upregulation of TNF-α and IL-6. Lactulose decreases the degree of DNA damage. Lactulose exhibits many of the properties of other oligosaccharides, including increasing the numbers of Bifidobacteria in feces. Lactulose restores the structure and composition of the intestinal microbiota, mitigates inflammation, and suppresses inflammatory tumorigenesis in mice with colitis-associated cancer. Lactulose can be used in the research of constipation. | ||||||||||||||||||||
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Lactulose (Standard) | ≥98% | Lactulose (Standard) is the analytical standard of Lactulose. This product is intended for research and analytical applications. Lactulose (4-O-β-D-Galactopyranosyl-D-fructose) is a poorly absorbed sugar that can be used to study constipation and hepatic encephalopathy. The drug generally begins to take effect 8 to 12 hours after administration, but it may take two days to improve constipation. | ||||||||||||||||||||
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- [1]. Hiraishi K, et al. Lactulose Modulates the Structure of Gut Microbiota and Alleviates Colitis-Associated Tumorigenesis. Nutrients. 2022;14(3):649. Published 2022 Feb 3. [Content Brief]
- [2]. Rowland IR, et al. The effect of lactulose on DNA damage induced by DMH in the colon of human flora-associated rats. Nutr Cancer. 1996;26(1):37-47. [Content Brief]
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