72296-47-0
Chemical Structure
Apovincaminic acid hydrochloride salt
- CAS No.: 72296-47-0
- Formula:C20H23ClN2O2
- Molecular Weight:358.86
IUPAC Name: (41S,13aS)-13a-ethyl-2,3,41,5,6,13a-hexahydro-1H-indolo[3,2,1-de]pyrido[3,2,1-ij][1,5]naphthyridine-12-carboxylic acid hydrochloride
InChIKey: LXMYBTYOASVVKL-VDWUQFQWSA-N
SMILES: CC[C@@]12[C@@]3([H])C4=C(CCN3CCC2)C5=CC=CC=C5N4C(C(O)=O)=C1.[H]Cl
Biological Activity: Apovincaminic acid hydrochloride salt is the major metabolite of Vinpocetine (HY-13295), with blood-brain barrier permeability and oral activity. Apovincaminic acid hydrochloride salt is detectable in the plasma of pregnant rabbits after oral administration of Vinpocetine. Apovincaminic acid hydrochloride salt is absorbable from all segments of the gastrointestinal tract of Norway rat, with the stomach as the primary absorption site, and is excreted via urine and feces. Apovincaminic acid hydrochloride salt is used in the research of cerebrovascular diseases[1][2].
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Apovincaminic acid hydrochloride salt | 96.93% | Apovincaminic acid hydrochloride salt is the major metabolite of Vinpocetine (HY-13295), with blood-brain barrier permeability and oral activity. Apovincaminic acid hydrochloride salt is detectable in the plasma of pregnant rabbits after oral administration of Vinpocetine. Apovincaminic acid hydrochloride salt is absorbable from all segments of the gastrointestinal tract of Norway rat, with the stomach as the primary absorption site, and is excreted via urine and feces. Apovincaminic acid hydrochloride salt is used in the research of cerebrovascular diseases. | ||||||||||||||||||||
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Apovincaminic acid hydrochloride salt (Standard) | ≥98% | Apovincaminic acid hydrochloride salt (Standard) is the analytical standard of Apovincaminic acid hydrochloride salt (HY-133813A). This product is intended for research and analytical applications. Apovincaminic acid hydrochloride salt is the major metabolite of Vinpocetine (HY-13295), with blood-brain barrier permeability and oral activity. Apovincaminic acid hydrochloride salt is detectable in the plasma of pregnant rabbits after oral administration of Vinpocetine. Apovincaminic acid hydrochloride salt is absorbable from all segments of the gastrointestinal tract of Norway rat, with the stomach as the primary absorption site, and is excreted via urine and feces. Apovincaminic acid hydrochloride salt is used in the research of cerebrovascular diseases. | ||||||||||||||||||||
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- [1]. Catlin N, et al. Embryo-fetal development studies with the dietary supplement vinpocetine in the rat and rabbit. Birth defects research. 2018 Jun 01;110(10):883-896. [Content Brief]
- [2]. Pudleiner P, et al. Study on the absorption of vinpocetine and apovincaminic acid. European journal of drug metabolism and pharmacokinetics. 1993;18(4):317-21. [Content Brief]
