2553218-46-3
Chemical Structure
Gut restricted-7
Synonym(s): GR-7
- CAS No.: 2553218-46-3
- Formula:C25H40FNaO6S
- Molecular Weight:510.63
IUPAC Name: sodium (3R,5R,7R,8R,9S,10S,13R,14S,17R)-17-((R)-6-fluoro-5-oxohexan-2-yl)-7-hydroxy-10,13-dimethylhexadecahydro-1H-cyclopenta[a]phenanthren-3-yl sulfate
InChIKey: GVCGSXGVFOXFAT-CTSSCMOWSA-M
SMILES: O=C(CF)CC[C@@H](C)[C@@]1([H])CC[C@@]2([H])[C@]3([H])[C@H](O)C[C@]4([H])C[C@H](OS(=O)(O[Na])=O)CC[C@]4(C)[C@@]3([H])CC[C@@]21C
Biological Activity: Gut restricted-7 (GR-7) is a potent, covalent and orally active pan-bile salt hydrolase (BSH) inhibitor. Gut restricted-7 has a tissue-selective and is restricted to the gut. Gut restricted-7 decreases gut bacterial BSHs and decreases deconjugated bile acid levels in feces of mice[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Gut restricted-7 | 99.54% | Gut restricted-7 (GR-7) is a potent, covalent and orally active pan-bile salt hydrolase (BSH) inhibitor. Gut restricted-7 has a tissue-selective and is restricted to the gut. Gut restricted-7 decreases gut bacterial BSHs and decreases deconjugated bile acid levels in feces of mice. | ||||||||||||||||||||
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