646-07-1
646-07-1
Chemical Structure
4-Methylpentanoic acid
Synonym(s): Isocaproic acid
- CAS No.: 646-07-1
- Formula:C6H12O2
- Molecular Weight:116.16
IUPAC Name: 4-methylpentanoic acid
InChIKey: FGKJLKRYENPLQH-UHFFFAOYSA-N
SMILES: CC(C)CCC(O)=O
Biological Activity:
4-Methylpentanoic acid (Isocaproic Acid) is a short-chain fatty acid and a metabolite of 20 α-hydroxycholesterol (HY-12316) that can be detected in feces. The concentration of 4-Methylpentanoic acid is closely associated with several diseases, such as depression. 4-Methylpentanoic acid is also applicable to studies on cholesterol metabolism[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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4-Methylpentanoic acid | 99.15% | 4-Methylpentanoic acid (Isocaproic Acid) is a short-chain fatty acid and a metabolite of 20 α-hydroxycholesterol (HY-12316) that can be detected in feces. The concentration of 4-Methylpentanoic acid is closely associated with several diseases, such as depression. 4-Methylpentanoic acid is also applicable to studies on cholesterol metabolism. |
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4-Methylpentanoic acid (Standard) | 99.14% | 4-Methylpentanoic acid (Isocaproic acid) (Standard) is an analytical standard form of 4-Methylpentanoic acid (HY-W015882). This product is intended for research and analytical applications. 4-Methylpentanoic acid (Isocaproic Acid) is a short-chain fatty acid, an endogenous metabolite, and a metabolite of 20 α-hydroxycholesterol (HY-12316), which can be found in feces. The concentration of 4-Methylpentanoic acid is closely related to some diseases, such as depression. 4-Methylpentanoic acid can also be used in the research of cholesterol metabolism. | ||||||||||||||||||||
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4-Methylpentanoic acid-d11 | 99.28% | 4-Methylpentanoic acid-d11 (Isocaproic Acid-d11) is the deuterium labeled 4-Methylpentanoic acid. 4-Methylpentanoic acid is a short-chain fatty acid and a metabolite of 20 α-hydroxycholesterol (HY-12316) that can be detected in feces. The concentration of 4-Methylpentanoic acid is closely associated with several diseases, such as depression. 4-Methylpentanoic acid is also applicable to studies on cholesterol metabolism. |
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5-Hydroxyhexanoic acid | 5-Hydroxyhexanoic acid is a normal monohydroxy carboxylic acid degradation product of fatty acids with medium chain lengths (particularly hexanoic acid). 5-Hydroxyhexanoic acid functions as a predictor of early renal functional decline in type 2 diabetes with microalbuminuria. |
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(±)-Leucine-d10 | 98.0% | (±)-Leucine-d10 is the deuterium labeled (±)-Leucine. (±)-Leucine (DL-Leucine), an isomer of Leucine, chemosterilant and dietary additive. (±)-Leucine inhibits growth of Escherichia coli HfrH by 92.08%. | ||||||||||||||||||||
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L-Alloisoleucine-d10 | L-Alloisoleucine-d10 is the deuterium labeled L-Alloisoleucine. L-Alloisoleucine is a branched chain amino acid and is a stereo-isomer of L-isoleucine. L-Alloisoleucine is a common constituent of human plasma (albeit at low levels). | |||||||||||||||||||||
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DL-Isoleucine-d10 | 98.6% | DL-Isoleucine-d10 is the deuterium labeled L-Isoleucine. L-isoleucine is a nonpolar hydrophobic amino acid. L-Isoleucine is an essential amino acid. | ||||||||||||||||||||
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L-Isoleucine-d10 | 99.89% | L-Isoleucine-d10 is the deuterium labeled L-Isoleucine. L-isoleucine is a nonpolar hydrophobic amino acid. L-Isoleucine is an essential amino acid. | ||||||||||||||||||||
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L-Isoleucine-13C6,15N,d10 | 99.9% | L-Isoleucine-13C6,15N,d10 is the deuterium, 13C-, and 15-labeled L-Isoleucine. L-isoleucine is a nonpolar hydrophobic amino acid. L-Isoleucine is an essential amino acid. | ||||||||||||||||||||
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4-Methyloctanoic acid (Standard) | ≥98% | 4-Methyloctanoic acid (Standard) is the analytical standard of 4-Methyloctanoic acid (HY-W010178). This product is intended for research and analytical applications. 4-Methyloctanoic acid is an endogenous branched-chain medium-chain fatty acid and a negative regulator of the cAMP/PKA signaling pathway. 4-Methyloctanoic acid exerts antiepileptic effects by inhibiting epileptiform discharges and terminating behavioral and electroencephalographic seizures. 4-Methyloctanoic acid has neuroprotective effects; its polar metabolites can cross the blood-brain barrier, repair presynaptic release defects, improve motor function and alleviate neuromuscular degeneration in ALS models. 4-Methyloctanoic acid regulates phosphatidylinositol metabolism, reduces PIP/PIP2 levels and increases inositol levels. 4-Methyloctanoic acid can be used in studies related to epilepsy and amyotrophic lateral sclerosis. | ||||||||||||||||||||
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3-Methylvaleric acid (Standard) | 99.54% | 3-Methylvaleric acid (Standard) is an analytical standard form of 3-Methylvaleric acid (HY-W010513). This product is intended for research and analytical applications. 3-Methylvaleric Acid is a branched alkanoic acid. 3-Methylvaleric Acid can be utilized by Pseudomonas citronettotis as a sole carbon source for its growth. 3-Methylvaleric Acid derivatives exhibit anti-hyperalgesic and anticonvulsant activities. | ||||||||||||||||||||
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2-Methylvaleric acid | 99.98% | 2-Methylvaleric acid is a branched short-chain fatty acid (SCFA) produced by the metabolism of branched-chain amino acids by gut microbes. 2-Methylvaleric acid can be used as a potential biomarker for metabolic diseases such as type 2 diabetes, and its content is significantly reduced in the feces of diabetic mice. 2-Methylvaleric acid may regulate host energy metabolism and inflammatory response through G protein-coupled receptors (GPCRs) or histone deacetylase (HDAC) inhibition. 2-Methylvaleric acid can be used to study gut microbe-host interactions and metabolic diseases as a fecal biomarker. | ||||||||||||||||||||
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Isovaleric acid (Standard) | 99.81% | Isovaleric acid (Standard) is the analytical standard of Isovaleric acid. This product is intended for research and analytical applications. Isovaleric acid is an oral active short-chain fatty acid that inhibits osteoclast differentiation by stimulating AMPK phosphorylation and promotes colonic smooth muscle relaxation by activating the cAMP/PKA pathway. Isovaleric acid can be used in research on skeletal diseases (such as osteoporosis) and intestinal disorders. | ||||||||||||||||||||
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Isovaleric acid-d9 | 99.27% | Isovaleric acid-d9 is the deuterium labeled Isovaleric acid. Isovaleric acid is a natural fatty acid and known to effect on neonatal death and possible Jamaican vomiting sickness in human. | ||||||||||||||||||||
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Isovaleric acid-13C | 99.0% | Isovaleric acid-13C is the 13C labeled Isovaleric acid. Isovaleric acid is a natural fatty acid and known to effect on neonatal death and possible Jamaican vomiting sickness in human. | ||||||||||||||||||||
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2,2-Dimethylbutanoic acid-d11 | 99.09% | 2,2-Dimethylbutanoic acid-d11 is the deuterium labeled 2,2-Dimethylbutanoic acid. | ||||||||||||||||||||
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4-Methylpentanoic acid-d12 | 99.25% | 4-Methylpentanoic acid-d12 (Isocaproic Acid-d12) is the deuterium labeled 4-Methylpentanoic acid. 4-Methylpentanoic acid is a short-chain fatty acid and a metabolite of 20 α-hydroxycholesterol (HY-12316) that can be detected in feces. The concentration of 4-Methylpentanoic acid is closely associated with several diseases, such as depression. 4-Methylpentanoic acid is also applicable to studies on cholesterol metabolism. |
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6-Methylheptanoic acid | 95.76% | 6-Methylheptanoic acid is an ester product. | ||||||||||||||||||||
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8-Methylnonanoic acid | 8-Methylnonanoic acidIt is an organic compound belonging to fatty acids. It has a faint waxy smell and is commonly found in a variety of foods, such as cheese and butter. 8-Methylnonanoic acidIt has various applications in the chemical and pharmaceutical industries, especially as an intermediate in the synthesis of various chemicals and pharmaceuticals. In addition, it can also be used as a flavoring agent in food. | |||||||||||||||||||||
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2,6-Dimethylheptanoic acid | 2,6-Dimethylheptanoic acid is an ester product. | |||||||||||||||||||||
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Methyl 4-methylpentanoate | 99.25% | Methyl 4-methylpentanoate (Methyl isohexanoate) is a natural product. Methyl 4-methylpentanoate can be isolated from the essential oil of Bourbon geranium (Pelargonium sp.) from Reunion. | ||||||||||||||||||||
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D-Leucine-d10 | 99.96% | D-Leucine-d10 is the deuterium labeled D-Leucine. D-Leucine is a more potent anti-seizure agent than L-leucine. D-leucine potently terminates seizures even after the onset of seizure activity. D-leucine, but not L-leucine, reduces long-term potentiation but had no effect on basal synaptic transmission in vitro. | ||||||||||||||||||||
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References
- [1]. Api AM, et al. RIFM fragrance ingredient safety assessment, 4-methylpentanoic acid, CAS Registry Number 646-07-1. Food Chem Toxicol. 2020;144 Suppl 1:111456. [Content Brief]
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[2]. Shimizu K, et al. Isocaproic acid, a metabolite of 20α-hydroxycholesterol. Journal of Biological Chemistry. 1960 Jun 1;235(6):PC25.
