Search Result

Results for "

fluorescent peptide

" in MedChemExpress (MCE) Product Catalog:

By Targets:	Amyloid-β (3) Fluorescent Dye (103) Peptide-Drug Conjugates (PDCs) (2) Angiotensin-converting Enzyme (ACE) (2) Apoptosis (1) Autophagy (1) Bacterial (4) Bcl-2 Family (1) Beta-secretase (2) Biochemical Assay Reagents (15) Bombesin Receptor (1) Caspase (5) Cathepsin (1) DNA Stain (1) Drug Intermediate (1) E1/E2/E3 Enzyme (1) EBV (2) EGFR (2) GLP Receptor (2) HDAC (2) HIV (2) Insulin Receptor (1) Integrin (5) Isotope-Labeled Compounds (1) Liposome (4) MetAP (1) MMP (7) Neurokinin Receptor (1) NF-κB (1) p38 MAPK (1) PKA (1) Potassium Channel (1) Proteasome (2) Radionuclide-Drug Conjugates (RDCs) (1) Reference Standards (1) Ser/Thr Protease (2) Sirtuin (2) STAT (2) Thrombin (2) α-synuclein (1)
By Research Areas:	Cancer (26) Infection (7) Inflammation/Immunology (5) Metabolic Disease (3) Neurological Disease (12)
Click Chemistry:	DBCO (2) Azide (1)

156

Inhibitors & Agonists

Fluorescent Dyes

Biochemical Assay Reagents

Peptides

Isotope-Labeled Compounds

Click Chemistry

Targets Recommended: Fluorescent Dye RXFP Receptor Formyl Peptide Receptor (FPR) Peptide-Drug Conjugates (PDCs) Natriuretic Peptide Receptor (NPR) Connective Peptide CGRP Receptor Amyloid-β

Cat. No.	Product Name	Target	Research Areas	Chemical Structure

HY-D0017

Dansyl chloride DNSCl	Fluorescent Dye	Others
Dansyl chloride is a reagent that produces stable blue or blue-green fluorescent sulfonamide adducts in the reaction of aliphatic and aromatic amines with primary amino groups, and is widely used for modified amino acids, protein sequencing and amino acid analysis .

HY-66022

5-FAM 4 Publications Verification 5-Carboxyfluorescein	Fluorescent Dye	Others
5-FAM (5-Carboxyfluorescein) is a green fluorescent reagent used for in situ labeling peptides, proteins and nucleotides. 5-FAM is a single isomer with Ex/Em of 490 nm/520 nm .

HY-138200

Cy5 maleimide 1 Publications Verification Cyanine5 maleimide	DNA Stain Fluorescent Dye	Others
Cy5 maleimide (Cyanine5 maleimide) is a single-reactive dye containing a maleimide group and a CY5 fluorescent group, which can selectively couple with a thiol group. Cy5 maleimide can be used to label antibodies, peptides, or proteins (Ex/Em = 646/664 nm).

HY-15944

5(6)-TAMRA 3 Publications Verification 5(6)-Carboxytetramethylrhodamine	Fluorescent Dye	Others
5(6)-TAMRA (5(6)-Carboxytetramethylrhodamine) is a fluorescent dye molecule widely used as a label for peptides and proteins (Ex/Em = 520/600 nm).

HY-D0715

Fluorescamine 1 Publications Verification Ro 20-7234	Fluorescent Dye	Others
Fluorescamine is a spirocyclic compound that is non-fluorescent. Fluorescamine reacts rapidly with primary amine groups in proteins under alkaline conditions to generate products with strong fluorescence (Ex/Em: 390/475 nm). Fluorescamine can be used to detect amine-containing compounds, including amino acids, peptides, and proteins .

HY-135414

Cyanine5 NHS ester chloride 1 Publications Verification	Fluorescent Dye	Others
Cyanine5 NHS ester chloride is a red emitting fluorescent dye for labeling of amino-groups in peptides, proteins, and oligonucleotides .

HY-15938

5-FAM SE	Fluorescent Dye	Others
5-FAM SE is a single isomer, is a fluorescent labeling reagent used for labeling peptides, proteins and nucleotides. 5-FAM SE can react with amines and can yield stable amine conjugates .

HY-79647

Fmoc-OSu N-(Fmoc-oxy)succinimide	Biochemical Assay Reagents	Others
Fmoc-OSu (N-(Fmoc-oxy)succinimide) is an acylating agent that targets amino groups (-NH2). It can selectively protect the amino groups of amino acids by covalently binding with primary or secondary amines through nucleophilic substitution reactions. Fmoc-OSu forms a stable amide bond with the amino group to avoid side reactions of the amino group in peptide synthesis. It can also be used as a fluorescent labeling reagent to react with glycosylamines for efficient labeling of N-sugar chains. Fmoc-OSu can be used as an Fmoc protection strategy in peptide synthesis, and as a fluorescent labeling and analysis method for N-sugar chains .

HY-P4931

Mca-KPLGL-Dap(Dnp)-AR-NH2 1 Publications Verification	MMP	Cancer
Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 (FS-6) is a fluorescent peptide that is a quenched MMP peptide substrate. Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 can be used for real-time quantification of MMP enzymatic activity. Mca-Lys-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 is an elongated peptide of MMP substrate (FS-1) and is active against collagenases (MMP-1, MMP-8, MMP-13 ) and MT1-MMP with higher specificity constants than FS-1 . (Ex/Em=325 nm/400 nm)

HY-129420

WSP-5	Fluorescent Dye	Cancer
WSP-5 is a H₂S-selective fluorescent probe (Ex/Em = 502/525 nm). WSP-5 enables visual monitoring of H₂S released and accumulated from peptide-H₂S donor conjugates in glioma cells. WSP-5 is applicable to glioma research .

HY-P4154

Bevonescein ALM-488	Fluorescent Dye	Neurological Disease Cancer
Bevonescein (ALM-488) is a fluorescein-conjugated peptide that facilitates the targeted delivery of a fluorescent moiety (5-FAM (HY-66022)) to nerves after intravenous (IV) administration. Bevonescein binds nerve-associated connective tissue, labels peripheral nerves under real-time fluorescence imaging (FL) in living mice and human ex vivo nerve tissue. Bevonescein is a peptide-linked tracer which fluorescently labeled both intact and degenerated nerves (Ex/Em = 480/530 nm) .

HY-D1872

800CW NHS ester	Fluorescent Dye	Others
800CW NHS ester is a near-infrared fluorescent dye active ester that can conjugate with amine-containing small molecules, antibodies, peptides, and other substances to form fluorescent conjugates. 800CW NHS ester exhibits high fluorescence quantum yield and low non-specific binding properties. 800CW NHS ester can be used in biomedical research such as microbial infection imaging, tumor imaging, and biochemical detection .

HY-15940

5(6)-Carboxyfluorescein 5 Publications Verification 5(6)-FAM; 5-(and-6)-Carboxyfluorescein mixed isomers	Fluorescent Dye	Cancer
5(6)-Carboxyfluorescein (5(6)-FAM) is an amine-reactive pH-sensitive green fluorescent probe. 5(6)-Carboxyfluorescein (5(6)-FAM) can be used to label proteins, peptides and nucleotides. 5(6)-Carboxyfluorescein can be used for the detection of tumour areas in vivo .

HY-D1849

Cy3B NHS ester	Fluorescent Dye	Others
Cy3B NHS ester is a fluorescent dye compound that is commonly used in biomarking and fluorescent labeling experiments, especially for labeling biomolecules containing amino functional groups (amine groups), such as proteins, antibodies or peptides.

HY-W027544

MCA 7-Methoxycoumarin-4-acetic acid	Fluorescent Dye	Others
MCA (7-Methoxycoumarin-4-acetic acid) is a Coumarin (HY-N0709) derivative. MCA quantitates platelet-activating factor (PAF) by high-performance liquid chromatography with fluorescent detection. MCA can modify FRET peptide substrates for analyzing protease activities .

HY-D0154

6-TRITC Tetramethylrhodamine-6-isothiocyanate	Fluorescent Dye	Others
6-TRITC (Tetramethylrhodamine-6-isothiocyanate) is a potent fluorescent tracer. 6-TRITC can be used as an probe for haptenated proteins/peptides for the research of contact allergy. 6-TRITC can be used as a tracer for the confocal imaging in living cells .

HY-P4344

Met-Gly-Pro-AMC	MetAP	Others
Met-Gly-Pro-AMC is a fluorescent peptide substrate of MetAP2 .

HY-P5287

cRGDfK-thioacetyl ester	Integrin	Cancer
cRGDfK-thioacetyl ester is a bioactive polypeptide molecule. cRGDfK peptide has a selective affinity for integrins. cRGDfK peptide can modify NIR fluorescent probes for cancer targeting imaging .

HY-D1800

Vari Fluor 680 SE VF 680 SE	Fluorescent Dye	Others
Vari Fluor 680 SE (VF 680 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=680 nm/700 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.

HY-D1801

Vari Fluor 488 SE VF 488 SE	Fluorescent Dye	Others
Vari Fluor 488 SE (VF 488 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=488 nm/513 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.

HY-P10202

5-FAM-GpYLPQTV-NH2	STAT	Cancer
5-FAM-GpYLPQTV-NH2 is a fluorescently labeled peptide and has STAT3 inhibitory activity. 5-FAM-GpYLPQTV-NH2 can be used in cancer research .

HY-171179

BD-Oligo	Fluorescent Dye	Neurological Disease
BD-Oligo is an oligomer-specific fluorescent chemical probe. BD-Oligo preferentially identifies Aβ oligomer assemblies over monomers or fibrils by using diversity-directed fluorescent library (DOFL) screening and computational techniques. BD-Oligo exhibits dynamic oligomer monitoring capabilities during Aβ peptide fibril formation as Aβ is induced to form oligomers and ultimately fibrils over time. BD-Oligo also exhibits blood-brain barrier permeability with the ability to stain Aβ oligomers in vivo .

HY-125372

2-Amino benzamidoxime ABAO	Biochemical Assay Reagents	Others
2-Amino benzamidoxime (ABAO) acts as a bioconjugation reagent precursor and a fluorescent probe precursor. 2-Amino benzamidoxime contains an aniline group for imine activation of aldehydes, as well as a nucleophilic group (Nu:) located at the ortho position of the amine, which is responsible for intramolecular cyclization. 2-Amino benzamidoxime reacts with glyoxal at the N-terminus of phage-displayed peptide libraries. Derivatives of 2-Amino benzamidoxime can be used for protein bioconjugation. Derivatives of 2-Amino benzamidoxime serve as fluorescent probes .\n

HY-P1188

LDV-FITC	Integrin	Cancer
LDV-FITC, a fluorescent peptide, is a FITC-conjugated LDV peptide (HY-P2267). LDV-FITC binds to the α4β1 integrin with high affinity (K_d: 0.3 nM and 12 nM for binding to U937 cells in the presence and absence of Mn ²⁺ respectively). LDV-FITC can be used to detect α4β1 integrin affinity .

HY-P1362F

Cy5-β-Amyloid (42-1), human Tris Cy5-Amyloid β peptide (42-1)(human) Tris	Amyloid-β	Neurological Disease
Cy5-β-Amyloid (42-1), human is a Cy5 fluorescently-labelled β-Amyloid (42-1, human) peptide (λ_ex= 633 nm and λ_em= 670 nm) .

HY-137367

Z-Val-Val-Arg-AMC	Cathepsin	Infection
Z-Val-Val-Arg-AMC is a fluorescent peptide substrate that can be used to test the activity of cathepsins .

HY-P2550A

β-Amyloid (1-40), FAM-labeled TFA	Amyloid-β	Neurological Disease
β-Amyloid (1-40), FAM-labeled TFA is a FAM fluorescently-labelled β-Amyloid (1-40) peptide (λex= 492 nm and λem= 518 nm).

HY-D2498

Cy7 maleimide	Fluorescent Dye	Others
Cy7 maleimide is a fluorescent dye containing a Maleimide (HY-W007324) functional group. Maleimide can be used to label thiol groups on antibodies, proteins and peptides .

HY-P4349A

Pyr-Arg-Thr-Lys-Arg-AMC TFA	Biochemical Assay Reagents Thrombin	Others
Pyr-Arg-Thr-Lys-Arg-AMC TFA is a AMC peptide, and a fluorescent substrate. Pyr-Arg-Thr-Lys-Arg-AMC TFA can be used to detect the activity of specific proteases, such as Furin, Trypsin, and Thrombin .

HY-D2441

TAT-PEG-Cy3	Fluorescent Dye	Cancer
TAT-PEG-Cy3 is a fluorescent labeling reagent that combines Cy3 fluorescent dye, Cell membrane penetrating peptide (TAT) and polyethylene glycol (PEG). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. TAT-PEG-Cy3 can be used for cell targeted delivery and biological imaging .

HY-D1802

Vari Fluor 425 SE VF 425 SE	Fluorescent Dye	Others
Vari Fluor 425 SE (VF 425 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=430 nm/475 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.

HY-D1790

Vari Fluor 640 SE VF 640 SE	Fluorescent Dye	Others
Vari Fluor 640 SE (VF 640 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=648 nm/664 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.

HY-P10172

Abz-SDK(Dnp)P-OH	Angiotensin-converting Enzyme (ACE)	Neurological Disease
Abz-SDK(Dnp)P-OH is a fluorescence peptide. Abz-SDK(Dnp)P-OH is the substrate of angiotensin I-converting enzyme (ACE). Abz-SDK(Dnp)P-OH has fluorescent donor-acceptor pair Abz and Dnp (2,4-dinitrophenyl) .

HY-D1423

Dibromobimane	Fluorescent Dye	Others
Dibromobimane is a thiol-selective fluorescent imaging agent. Dibromobimane is used to crosslink cysteine- and homocysteine-containing peptides .

HY-135414B

Cyanine5 NHS ester iodide 1 Publications Verification	Fluorescent Dye	Others
Cyanine5 NHS ester iodide is a red emitting fluorescent dye for labeling of amino-groups in peptides, proteins, and oligonucleotides .

HY-P2550

β-Amyloid (1-40), FAM-labeled	Amyloid-β	Neurological Disease
β-Amyloid (1-40), FAM-labeled is a FAM fluorescently-labelled β-Amyloid (1-40) peptide (λ_ex= 492 nm and λ_em= 518 nm) .

HY-D2439

RGD-PEG-Cy3	Fluorescent Dye	Cancer
RGD-PEG-Cy3 is a fluorescent labeling reagent that combines Cy3 fluorescent dye, peptide (RGD) and polyethylene glycol (PEG). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. RGD is a peptide sequence (CRGDKGPDCiRGD) that binds to αvβ3 and αvβ5 integrin receptors on tumor neovasculogenesis to achieve specific tumor tissue targeting .

HY-P5378A

Ac-KQKLR-AMC TFA Cathepsin S substrate TFA	Ser/Thr Protease	Others
Ac-KQKLR-AMC TFA is a substrate peptide of Cathepsin S fluorescently labeled with AMC (Ex/Em=354 nm/442 nm). Ac-KQKLR-AMC TFA can be used to measure Cathepsin S activity) .

HY-P10772

L2P4	Peptide-Drug Conjugates (PDCs) EBV	Cancer
L2P4 is a peptide-based and EBNA1 targeting fluorescent probe, which inhibits the EBNA1 homodimer formation and selectively inhibits EBV+ tumor growth. L2P4 exhibits cytotoxicity in EBV-positive C666-1 cell with LC₅₀ of 46.4 μM .

HY-P10772A

L2P4 TFA	Peptide-Drug Conjugates (PDCs) EBV	Cancer
L2P4 TFA is a peptide-based and EBNA1 targeting fluorescent probe, which inhibits the EBNA1 homodimer formation and selectively inhibits EBV+ tumor growth. L2P4 TFA exhibits cytotoxicity in EBV-positive C666-1 cell with LC₅₀ of 46.4 μM .

HY-D1791

Vari Fluor 750 SE VF 750 SE	Fluorescent Dye	Others
Vari Fluor 750 SE (VF 750 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=747 nm/770 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.

HY-P3791

N-Succinyl-Ile-Ile-Trp-AMC	Fluorescent Dye	Others
N-Succinyl-Ile-Ile-Trp-AMC is a peptide-based fluorescent substrate or probe for carboxypeptidase Y (CPY) .

HY-W250725

H-GLU-AMC-OH	Fluorescent Dye	Neurological Disease
H-GLU-AMC-OH is an amino acid derivative that can be used as A fluorescent peptide substrate for the determination of aminopeptidase A enzyme activity .

HY-137834A

Gly-Pro-AMC	Biochemical Assay Reagents	Others
Gly-Pro-AMC is a biological active peptide. (This is a fluorescent dipeptidylaminopeptidase IV substrate, Abs/Em=353/442 nm.)

HY-P5355

Z-Gly-Gly-Arg-AFC	Fluorescent Dye	Others
Z-Gly-Gly-Arg-AFC is a biological active peptide. (Plasminogen Activator Acrosine Substrate, fluorescent Z-Gly-Gly-Arg-AFC)

HY-P3364

Ac-QPKK(Ac)-AMC	Fluorescent Dye Sirtuin HDAC	Others
Ac-QPKK(Ac)-AMC is a p53-derived peptide conjugated with a fluorophore, which serves as a fluorescent peptide substrate for detecting the deacylase activity of zinc-dependent HDACs and sirtuins (Ex = 360 nm; Em = 460 nm) .

HY-D2488

Sulfo Cy5.5-maleimide	Fluorescent Dye	Others
Sulfo Cy5.5-maleimide is a fluorescent dye containing a Maleimide (HY-W007324) functional group. Maleimide can be used to label thiol groups on antibodies, proteins and peptides.

HY-P5378

Ac-KQKLR-AMC Cathepsin S substrate	Ser/Thr Protease	Others
Ac-KQKLR-AMC is a substrate peptide of Cathepsin S fluorescently labeled with AMC (Ex/Em=354 nm/442 nm). Ac-KQKLR-AMC can be used to measure Cathepsin S activity) .

HY-P5367

5-FAM-PMDM6 PMDM6-F	Fluorescent Dye	Others
5-FAM-PMDM6 (PMDM6-F) is a biological active peptide. (PMDM6-F is a fluorescent-labeled probe for MDM2-binding assay.)

HY-P10202A

5-FAM-GpYLPQTV-NH2 TFA	STAT	Cancer
5-FAM-GpYLPQTV-NH2 (TFA) is a fluorescently labeled peptide and has STAT3 inhibitory activity. 5-FAM-GpYLPQTV-NH2 (TFA) can be used in cancer research .

Cat. No.	Product Name	Type

HY-66019

FITC

Maximum Cited Publications

92 Publications Verification

Fluorescein 5-isothiocyanate

Fluorescent Dyes

FITC (Fluorescein Isothiocyanate), is one of the green fluorescein derivatives widely used in biology. FITC has the characteristics of high absorptivity and excellent fluorescence quantum yield. The isothiocyanate group of FITC can be combined with amino, sulfhydryl, imidazole, tyrosyl, carbonyl and other groups on the protein, so as to achieve protein labeling including antibodies and lectins. In addition to its use as a protein marker, FITC can also be used as a fluorescent protein tracer to rapidly identify pathogens by labeling antibodies, or for microsequencing of proteins and peptides (HPLC). The maximum excitation wavelength of FITC is 494 nm. Once excited, it fluoresces yellow-green at a maximum emission wavelength of 520 nm. In addition, FITC is also a hapten that can induce contact hypersensitivity (CHS) and induce an atopic dermatitis model .

HY-D0017

Dansyl chloride DNSCl	Fluorescent Dyes
Dansyl chloride is a reagent that produces stable blue or blue-green fluorescent sulfonamide adducts in the reaction of aliphatic and aromatic amines with primary amino groups, and is widely used for modified amino acids, protein sequencing and amino acid analysis .

HY-66022

5-FAM 4 Publications Verification 5-Carboxyfluorescein	Fluorescent Dyes
5-FAM (5-Carboxyfluorescein) is a green fluorescent reagent used for in situ labeling peptides, proteins and nucleotides. 5-FAM is a single isomer with Ex/Em of 490 nm/520 nm .

HY-138200

Cy5 maleimide 1 Publications Verification Cyanine5 maleimide	Fluorescent Dyes
Cy5 maleimide (Cyanine5 maleimide) is a single-reactive dye containing a maleimide group and a CY5 fluorescent group, which can selectively couple with a thiol group. Cy5 maleimide can be used to label antibodies, peptides, or proteins (Ex/Em = 646/664 nm).

HY-15944

5(6)-TAMRA 3 Publications Verification 5(6)-Carboxytetramethylrhodamine	Fluorescent Dyes
5(6)-TAMRA (5(6)-Carboxytetramethylrhodamine) is a fluorescent dye molecule widely used as a label for peptides and proteins (Ex/Em = 520/600 nm).

HY-D0715

Fluorescamine 1 Publications Verification Ro 20-7234	Fluorescent Dyes
Fluorescamine is a spirocyclic compound that is non-fluorescent. Fluorescamine reacts rapidly with primary amine groups in proteins under alkaline conditions to generate products with strong fluorescence (Ex/Em: 390/475 nm). Fluorescamine can be used to detect amine-containing compounds, including amino acids, peptides, and proteins .

HY-D0098

Fluorescein-5-maleimide

5 Publications Verification

N-(5-Fluoresceinyl)maleimide

Fluorescent Dyes

Fluorescein-5-maleimide (N-(5-Fluoresceinyl)maleimide) is a fluorescent dye. Fluorescein-5-maleimide can be used to detect the redox state of thiols in eukaryotic cells. Fluorescein-5-maleimide can label peptides and is used to detect negatively charged nanoparticles. Fluorescein-5-maleimide can also label actin to explore its interaction with cardiac myosin-binding protein C (cMyBP-C), which helps in developing small molecule modulators for heart failure. Fluorescein-5-maleimide can screen mutant proteins that contain cysteine residues. The excitation wavelength of Fluorescein-5-maleimide is 494 nm, and the emission wavelength is 519 nm .

HY-135414

Cyanine5 NHS ester chloride 1 Publications Verification	Fluorescent Dyes
Cyanine5 NHS ester chloride is a red emitting fluorescent dye for labeling of amino-groups in peptides, proteins, and oligonucleotides .

HY-15938

5-FAM SE	Fluorescent Dyes
5-FAM SE is a single isomer, is a fluorescent labeling reagent used for labeling peptides, proteins and nucleotides. 5-FAM SE can react with amines and can yield stable amine conjugates .

HY-129420

WSP-5	Fluorescent Dyes
WSP-5 is a H₂S-selective fluorescent probe (Ex/Em = 502/525 nm). WSP-5 enables visual monitoring of H₂S released and accumulated from peptide-H₂S donor conjugates in glioma cells. WSP-5 is applicable to glioma research .

HY-131498

MOCAc-PLGL(Dpa)AR

Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2

Fluorescent Dyes

MOCAc-PLGL (Dpa) AR (Mca-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH₂) is a synthetic fluorescent substrate mainly used for in vitro enzymatic activity assays of MMP-7 (detection at 393 nm after excitation at 328 nm). MOCAc-PLGL (Dpa) AR is specifically cleaved and hydrolyzed by MMP-7 at the Gly-Leu peptide bond, allowing enzymatic activity to be monitored via fluorometry or HPLC (DMSO is usually added to ensure sufficient dissolution when determining kinetic parameters). MOCAc-PLGL (Dpa) AR is used to accurately evaluate the catalytic activity and pH dependence of recombinant mature human MMP-7 in vitro. MOCAc-PLGL (Dpa) AR is suitable for research on the mechanisms of tumor metastasis and invasion, particularly in fields such as prostate cancer, colon cancer, lung cancer and breast cancer .\n

HY-D1872

800CW NHS ester

Fluorescent Dyes

800CW NHS ester is a near-infrared fluorescent dye active ester that can conjugate with amine-containing small molecules, antibodies, peptides, and other substances to form fluorescent conjugates. 800CW NHS ester exhibits high fluorescence quantum yield and low non-specific binding properties. 800CW NHS ester can be used in biomedical research such as microbial infection imaging, tumor imaging, and biochemical detection .

HY-15940

5(6)-Carboxyfluorescein 5 Publications Verification 5(6)-FAM; 5-(and-6)-Carboxyfluorescein mixed isomers	Fluorescent Dyes
5(6)-Carboxyfluorescein (5(6)-FAM) is an amine-reactive pH-sensitive green fluorescent probe. 5(6)-Carboxyfluorescein (5(6)-FAM) can be used to label proteins, peptides and nucleotides. 5(6)-Carboxyfluorescein can be used for the detection of tumour areas in vivo .

HY-D2906

Alexa fluor 647 maleimide

Fluorescent Dyes

Alexa fluor 647 maleimide is a bright, far-red-emitting fluorescent dye for labeling of protein SH groups (Ex/Em = 656/670 nm). Alexa fluor 647 maleimide can be used to attach AF 647 fluorophore to proteins and peptides containing cysteine residues, as well as to other thiolated molecules (such as thiol-containing oligonucleotides). Alexa Fluor 647 maleimide is promising for research of cell biology, neuroscience, and disease diagnostics .

HY-D1849

Cy3B NHS ester	Fluorescent Dyes
Cy3B NHS ester is a fluorescent dye compound that is commonly used in biomarking and fluorescent labeling experiments, especially for labeling biomolecules containing amino functional groups (amine groups), such as proteins, antibodies or peptides.

HY-W027544

MCA 7-Methoxycoumarin-4-acetic acid	Fluorescent Dyes
MCA (7-Methoxycoumarin-4-acetic acid) is a Coumarin (HY-N0709) derivative. MCA quantitates platelet-activating factor (PAF) by high-performance liquid chromatography with fluorescent detection. MCA can modify FRET peptide substrates for analyzing protease activities .

HY-DY1007

FITC (solution)

Fluorescent Dyes

FITC (Fluorescein Isothiocyanate) (solution) , is one of the green fluorescein derivatives widely used in biology. FITC has the characteristics of high absorptivity and excellent fluorescence quantum yield. The isothiocyanate group of FITC can be combined with amino, sulfhydryl, imidazole, tyrosyl, carbonyl and other groups on the protein, so as to achieve protein labeling including antibodies and lectins. In addition to its use as a protein marker, FITC can also be used as a fluorescent protein tracer to rapidly identify pathogens by labeling antibodies, or for microsequencing of proteins and peptides (HPLC). The maximum excitation wavelength of FITC is 494 nm. Once excited, it fluoresces yellow-green at a maximum emission wavelength of 520 nm. In addition, FITC is also a hapten that can induce contact hypersensitivity (CHS) and induce an atopic dermatitis model .
Solvent and concentration: DMSO: 20 mM
The 1 mL volume is defined as the base specification. All larger sizes correspond to incremental volumes of this base.

HY-D0154

6-TRITC Tetramethylrhodamine-6-isothiocyanate	Fluorescent Dyes
6-TRITC (Tetramethylrhodamine-6-isothiocyanate) is a potent fluorescent tracer. 6-TRITC can be used as an probe for haptenated proteins/peptides for the research of contact allergy. 6-TRITC can be used as a tracer for the confocal imaging in living cells .

HY-D1800

Vari Fluor 680 SE VF 680 SE	Fluorescent Dyes
Vari Fluor 680 SE (VF 680 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=680 nm/700 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.

HY-D1801

Vari Fluor 488 SE VF 488 SE	Fluorescent Dyes
Vari Fluor 488 SE (VF 488 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=488 nm/513 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.

HY-171179

BD-Oligo

Fluorescent Dyes

BD-Oligo is an oligomer-specific fluorescent chemical probe. BD-Oligo preferentially identifies Aβ oligomer assemblies over monomers or fibrils by using diversity-directed fluorescent library (DOFL) screening and computational techniques. BD-Oligo exhibits dynamic oligomer monitoring capabilities during Aβ peptide fibril formation as Aβ is induced to form oligomers and ultimately fibrils over time. BD-Oligo also exhibits blood-brain barrier permeability with the ability to stain Aβ oligomers in vivo .

HY-P1362F

Cy5-β-Amyloid (42-1), human Tris Cy5-Amyloid β peptide (42-1)(human) Tris	Fluorescent Dyes
Cy5-β-Amyloid (42-1), human is a Cy5 fluorescently-labelled β-Amyloid (42-1, human) peptide (λ_ex= 633 nm and λ_em= 670 nm) .

HY-D2498

Cy7 maleimide	Fluorescent Dyes
Cy7 maleimide is a fluorescent dye containing a Maleimide (HY-W007324) functional group. Maleimide can be used to label thiol groups on antibodies, proteins and peptides .

HY-D2441

TAT-PEG-Cy3

Fluorescent Dyes

TAT-PEG-Cy3 is a fluorescent labeling reagent that combines Cy3 fluorescent dye, Cell membrane penetrating peptide (TAT) and polyethylene glycol (PEG). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. TAT-PEG-Cy3 can be used for cell targeted delivery and biological imaging .

HY-D1802

Vari Fluor 425 SE VF 425 SE	Fluorescent Dyes
Vari Fluor 425 SE (VF 425 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=430 nm/475 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.

HY-D1790

Vari Fluor 640 SE VF 640 SE	Fluorescent Dyes
Vari Fluor 640 SE (VF 640 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=648 nm/664 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.

HY-D2062

ATTO 740 NHS ester

Fluorescent Dyes

ATTO 740 NHS ester is a near-infrared fluorescent dye and a multimodal fluorescence/photoacoustic contrast agent with excellent near-infrared emission properties and extremely high photostability. The photoacoustic signal of ATTO 740 NHS ester shows no significant decrease after continuous irradiation with a 750 nm laser for 30 min, making it suitable for in vivo fluorescence imaging and photoacoustic contrast imaging. When conjugated with the cystine knot peptide R01, ATTO 740 NHS ester enables precise detection of integrin αvβ6-positive cells and tumors in nude mouse xenograft models .

HY-D1423

Dibromobimane	Fluorescent Dyes
Dibromobimane is a thiol-selective fluorescent imaging agent. Dibromobimane is used to crosslink cysteine- and homocysteine-containing peptides .

HY-135414B

Cyanine5 NHS ester iodide 1 Publications Verification	Fluorescent Dyes
Cyanine5 NHS ester iodide is a red emitting fluorescent dye for labeling of amino-groups in peptides, proteins, and oligonucleotides .

HY-D2439

RGD-PEG-Cy3

Fluorescent Dyes

RGD-PEG-Cy3 is a fluorescent labeling reagent that combines Cy3 fluorescent dye, peptide (RGD) and polyethylene glycol (PEG). The Cy3 fluorophore is commonly used in applications such as immunolabeling, nucleic acid labeling, fluorescence microscopy, and flow cytometry. Cy3 has an emission maximum around 562-570 nm. RGD is a peptide sequence (CRGDKGPDCiRGD) that binds to αvβ3 and αvβ5 integrin receptors on tumor neovasculogenesis to achieve specific tumor tissue targeting .

HY-D1791

Vari Fluor 750 SE VF 750 SE	Fluorescent Dyes
Vari Fluor 750 SE (VF 750 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=747 nm/770 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.

HY-P3791

N-Succinyl-Ile-Ile-Trp-AMC	Fluorescent Dyes
N-Succinyl-Ile-Ile-Trp-AMC is a peptide-based fluorescent substrate or probe for carboxypeptidase Y (CPY) .

HY-137834A

Gly-Pro-AMC	Fluorescent Dyes
Gly-Pro-AMC is a biological active peptide. (This is a fluorescent dipeptidylaminopeptidase IV substrate, Abs/Em=353/442 nm.)

HY-D2488

Sulfo Cy5.5-maleimide	Fluorescent Dyes
Sulfo Cy5.5-maleimide is a fluorescent dye containing a Maleimide (HY-W007324) functional group. Maleimide can be used to label thiol groups on antibodies, proteins and peptides.

HY-D1596A

Cyanine 3.5 bromide Cy3.5 NHS ester bromide; Cy 3.5 bromide	Fluorescent Dyes
Cyanine 3.5 bromide (Cy3.5 NHS ester bromide) is an analog of the Cy3.5 fluorophore. Cyanine 3.5 bromide is a red reactive fluorescent dye. Cyanine 3.5 bromide is used to label amino groups in peptides, proteins, and oligonucleotides. (λ_ex=591 nm, λ_em=604 nm) .

HY-D2891

5-TAMRA-DBCO	Fluorescent Dyes
5-TAMRA-DBCO is a fluorescent dye that combines 5-TAMRA (HY-15942) with a dibenzocyclooctyne (DBCO) moiety. 5-TAMRA-DBCO is able to copper-free click chemistry reactions with azide-functionalized molecules. 5-TAMRA-DBCO can be used for labeling proteins, peptides, nucleic acids (Ex/Em = 541/567 nm) .

HY-D1993

ATTO 647 NHS ester

Fluorescent Dyes

ATTO 647 NHS ester is a fluorescent label targeting free amino groups. ATTO 647 NHS ester can undergo a nucleophilic reaction with the free amino groups of EF-C peptide via its activated carboxylic acid group to form a stable covalent conjugate. ATTO 647 NHS ester-labeled nanofibers not only retain retroviral transduction-enhancing activity but also maintain stable fluorescent signals in both buffer and cell culture systems. ATTO 647 NHS ester is suitable for detection applications including fluorescence spectroscopy, microscopy and flow cytometry. ATTO 647 NHS ester has been used in studies related to HIV-1 infection .

HY-W800701

BP Fluor 546 DBCO

Fluorescent Dyes

BP Fluor 546 DBCO is an azide-reactive probe that can be used for imaging azide-tagged biomolecules via a copper-free click reaction. The DBCO moiety reacts with azides to form a stable triazole and does not require a Cu-catalyst or elevated temperatures. In applications where the presence of copper is a concern, BP Fluor 546 DBCO is an ideal alternative to copper-requiring fluorescent alkynes. BP Fluor 546 is a water-soluble, pH-insensitive (from pH 4-10), orange-fluorescent dye with absorption and emission maxima at 554 and 570 nm, respectively. It can be used with the 488 nm and 532 nm laser lines. BP Fluor 546 dye conjugates to a variety of antibodies, peptides, proteins, tracers, and amplification substrates, which are often used for generating stable signals in imaging and flow cytometry.

HY-W039519

7-Methoxycoumarin-3-carboxylic acid	Fluorescent Dyes
7-Methoxycoumarin-3-carboxylic acid is a fluorescent dye with an excitation peak at 355 nm and an emission peak at 405 nm. 7-Methoxycoumarin-3-carboxylic acid can be used to label peptide .

HY-D1596

Cyanine 3.5 chloride Cy3.5 NHS ester chloride; Cy 3.5 chloride	Fluorescent Dyes
Cyanine 3.5 (Cy3.5 NHS ester) chloride is an analog of Cy3.5 fluorophore. Cyanine 3.5 chloride is a reactive, red fluorescent dye. Cyanine 3.5 chloride is used for labeling of amino-groups in peptides, proteins, and oligonucleotides. (λ_ex=591 nm, λ_em=604 nm) .

HY-D1611

BODIPY FL-C5 NHS Ester	Fluorescent Dyes
BODIPY FL-C5 NHS Ester is a green-fluorescent dye that is reactive with primary amines on biomolecules such as peptides, proteins, modified nucleotides and biopolymers .

HY-D1592

BODIPY TMR C5-maleimide	Fluorescent Dyes
BODIPY TMR C5-maleimide is a fluorescent dye. BODIPY TMR C5-maleimide is a high quantum yield fluorophore which can be coupled with peptides .

HY-137858

H-Gly-Arg-pNA hydrochloride Gly-Arg-4-NA hydrochloride; GR-pNA hydrochloride; GR p-itoailide hydrochloride	Fluorescent Dyes
H-Gly-Arg-pNA hydrochloride (GR-pNA hydrochloride) is a colorimetric substrate for thrombin. H-Gly-Arg-pNA is preferentially bound by thrombin and cleaves the Gly-Arg (GR) peptide sequence, releasing p-nitroaniline (pNA) that can be detected colorimetrically at 405 nm. H-Gly-Arg-pNA hydrochloride is used as a fluorescent dye to measure thrombin activity .

HY-D1798

Vari Fluor 350 SE VF 350 SE	Fluorescent Dyes
Vari Fluor 350 SE (VF 350 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=350 nm/448 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.

HY-D1796

Vari Fluor 594 SE VF 594 SE	Fluorescent Dyes
Vari Fluor 594 SE (VF 594 SE) is a dye marker of the Vari Fluor SE series (Ex/Em=585 nm/609 nm). The Vari Fluor SE series of dyes are a class of fluorescent dyes containing NHS ester groups used to label free amines (-NHX) on antibodies, proteins, peptides, amine-modified oligonucleotides and other biomolecules.

HY-D2772

5-TAMRA Cadaverine

Fluorescent Dyes

5-TAMRA cadaverine can used to modify carboxylic acid group in the presence of activators (e.g. EDC, or DCC) or activated esters (e.g. NHS esters) through a stable amide bond. It also can be reversibly coupled to aldehydes and ketones to form a Schiff base – which can be reduced to a generate stable amine derivative by sodium borohydride (NaBH4) or sodium cyanoborohydride (NaCNH3). Although the mixed isomers of 5(6)-TAMRA cadaverine is a preferred, routinely used orange-fluorescent dye for staining proteins, it is rearly used for labeling peptides and nucleotides. Purification of 5(6)-TAMRA labeled peptide and nucleotides might be troublesome due to significant signal broadening in HPLC purification. Peptides and nucleotides labeled with a single isomer TAMRA usually give better resolution in HPLC purification that is often required in the conjugation processes.

HY-D2745

BP Fluor 594 NHS ester

Fluorescent Dyes

BP Fluor 594 NHS ester is the most popular tool for modifying proteins or antibodies through the primary amines (Lys), amine-modified oligonucleotides, and other amine-containing biomolecules with BP Fluor 594 label. The labeling occurs most efficiently at pH 7-9 and forms a stable, covalent amide bond. BP Fluor 594 dye can be used for proteins labeling at high molar ratios without significant self-quenching, enabling brighter conjugates and more sensitive detection. BP Fluor 594 is bright, water-soluble, and pH-insensitive from pH 4 to pH 10 red-fluorescent dye with absorption and emission maxima at 590 and 617 nm, respectively. It can be used with the 561 nm and 594 nm laser lines. BP Fluor 594 dye conjugated to a variety of antibodies, peptides, proteins, tracers, and amplification substrates often used for generation of stable signal in imaging and flow cytometry.

HY-D2495

Cy7 SE (nosulfo)	Fluorescent Dyes
Cy7 SE (nosulfo) is a fluorescent dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides.

HY-W879234

TriSulfo-Cy5.5 DBCO Sulfo Cy5.5-DBCO	Fluorescent Dyes
TriSulfo-Cy5.5 DBCO is a near infrared (NIR) fluorescent anthocyanin fluorescent dye.TriSulfo-Cy5.5 DBCO can be used to label proteins, antibodies, peptides, nucleic acid molecules.

HY-D2290

Demethoxy-BODIPY TMR NHS ester	Fluorescent Dyes
Demethoxy-BODIPY TMR NHS ester is an amine-reactive fluorescent probe, and can be used for the labeling of proteins, peptides, and other molecules .

Cat. No.	Product Name	Type

HY-Y0623

N-Hydroxysuccinimide

5+ Cited Publications

HOSu; 1-Hydroxy-2,5-pyrrolidinedione

Biochemical Assay Reagents

N-Hydroxysuccinimide (HOSu; 1-Hydroxy-2,5-pyrrolidinedione) is a covalent crosslinker commonly used in bioconjugation technology with a primary amine group. N-Hydroxysuccinimide reacts with amino groups (-NH2) to form a stable amide bond, which can modify amino-containing biomolecules. N-Hydroxysuccinimide can be used, for example, for protein labeling with fluorescent dyes and enzymes, surface activation of chromatography supports, microbeads, nanoparticles and microarray slides, and chemical synthesis of peptides. N-Hydroxysuccinimide has a wide range of applications in biomaterial synthesis (such as collagen, chitosan crosslinking), drug delivery systems (such as hydrogel preparation) and tissue engineering .

HY-79647

Fmoc-OSu

N-(Fmoc-oxy)succinimide

Biochemical Assay Reagents

Fmoc-OSu (N-(Fmoc-oxy)succinimide) is an acylating agent that targets amino groups (-NH2). It can selectively protect the amino groups of amino acids by covalently binding with primary or secondary amines through nucleophilic substitution reactions. Fmoc-OSu forms a stable amide bond with the amino group to avoid side reactions of the amino group in peptide synthesis. It can also be used as a fluorescent labeling reagent to react with glycosylamines for efficient labeling of N-sugar chains. Fmoc-OSu can be used as an Fmoc protection strategy in peptide synthesis, and as a fluorescent labeling and analysis method for N-sugar chains .

Cat. No.	Product Name	Chemical Structure

HY-W027544S

MCA-d3
MCA-d₃ (7-Methoxycoumarin-4-acetic acid₃) is the deuterium labeled MCA (HY-W027544) . MCA is a Coumarin (HY-N0709) derivative. MCA quantitates platelet-activating factor (PAF) by high-performance liquid chromatography with fluorescent detection. MCA can modify FRET peptide substrates for analyzing protease activities .

Cat. No.	Product Name		Classification

HY-D2891

5-TAMRA-DBCO		DBCO
5-TAMRA-DBCO is a fluorescent dye that combines 5-TAMRA (HY-15942) with a dibenzocyclooctyne (DBCO) moiety. 5-TAMRA-DBCO is able to copper-free click chemistry reactions with azide-functionalized molecules. 5-TAMRA-DBCO can be used for labeling proteins, peptides, nucleic acids (Ex/Em = 541/567 nm) .

HY-W879234

TriSulfo-Cy5.5 DBCO Sulfo Cy5.5-DBCO		DBCO
TriSulfo-Cy5.5 DBCO is a near infrared (NIR) fluorescent anthocyanin fluorescent dye.TriSulfo-Cy5.5 DBCO can be used to label proteins, antibodies, peptides, nucleic acid molecules.

HY-P11757

Cyclo[K(N3)larllt]		Azide
Cyclo[K(N3)larllt] is a seven-membered cyclic peptide targeting EGFR, with a K_d value of 5.09 μM, and exhibits binding selectivity toward homologous proteins HER2 and HER3. Cyclo[K(N3)larllt] has no cytotoxicity and shows no growth inhibitory effect on cancer cells overexpressing EGFR. Cyclo[K(N3)larllt] can serve as a ligand for EGFR-targeted fluorescent conjugates, which is applicable to the detection of cancers with EGFR overexpression. Cyclo[K(N3)larllt] can be used in the research of colorectal cancer .

Inquiry Online

Your information is safe with us. * Required Fields.

MCE Japan Authorized Agent ナミキ商事株式会社コスモ・バイオ株式会社重松貿易株式会社
Salutation			Country or Region *
Applicant Name *			Organization Name *
Department *
Email Address *			Product Name *
Cat. No.			Requested quantity *
Phone Number *
Remarks

Inquiry Online

Inquiry Information

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent: