108 Results for "

glucan

" in MedChemExpress (MCE) Product Catalog:
Products (108)

108 Results for "glucan" in MCE Product Catalog:

21
21 Publications Verification
Cat. No.: HY-16321
CAS No.: 208538-73-2
Synonyms: FK 463 sodium
Target:  

Fungal Antibiotic

Research Areas:  

Infection Cancer

Micafungin sodium (FK 463 sodium) is an antifungal agent which inhibits 1, 3-beta-D-glucan synthesis.
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21
21 Publications Verification
Cat. No.: HY-17579
CAS No.: 235114-32-6
Synonyms: FK463
Target:  

Fungal Antibiotic

Research Areas:  

Infection Cancer

Micafungin (Mycamine; FK463) is an echinocandin antifungal drug which can inhibit 1,3-beta-D-glucan synthase.
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11
11 Cited Publications
Cat. No.: HY-17006
CAS No.: 179463-17-3
Synonyms: MK-0991 diacetate; L-743872 diacetate
Research Areas:  

Infection Cancer

Caspofungin (MK-0991) diacetate is a potent antifungal agent. Caspofungin diacetate inhibits the synthesis of the fungal cell wall component β-(l,3)-D-glucan .
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11
11 Cited Publications
Cat. No.: HY-17006A
CAS No.: 162808-62-0
Synonyms: MK-0991; L-743872
Research Areas:  

Infection Cancer

Caspofungin is a potent antifungal agent. Caspofungin inhibits the synthesis of the fungal cell wall component β-(l,3)-D-glucan .
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2
2 Cited Publications
Cat. No.: HY-W145521
CAS No.: 9051-97-2
Synonyms: β glucan
β-1,3-GlucanGlucan) is an orally active polysaccharide composed of glucose polymers. β-1,3-Glucan increase the activity of IKKβ kinase, enhances the production of nitric oxide. β-1,3-Glucan improves resistance to Vibrio harveyi infection. β-1,3-Glucan enhances immune response, promotes blood pressure recovery, reduces lung, kidney and liver damage, inhibits the growth of syngeneic tumors .
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2
2 Cited Publications
Cat. No.: HY-119109
CAS No.: 9008-22-4
Purity:  ≥98.0%
Laminaran is an β-1-3-glucan and a typical ligand for Dectin-1 from Eisenia Bicyclis, has potent immunomodulating, radioprotective, and anticancer activities . Laminaran is made up of β (1→3)-glucan with β (1→6)-branches and can be catalyzed by enzymes such as laminarinase (EC 3.2.1.6) that breaks the β (1→3) bonds . Laminaran is a promising immune stimulatory molecule for use in cancer immunotherapy .
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2
2 Cited Publications
Cat. No.: HY-158082C
Synonyms: Tetramethyl rhodamine isothiocyanate glucan, MW 70000
TRITC-dextran MW 70000 (Tetramethyl rhodamine isothiocyanate glucan, MW 70000) is a fluorescent dye with a molecular weight of 70 kD. The excitation wavelength of TRITC-dextran MW 70000 is 555 nm, and its emission wavelength is 570 nm. TRITC-dextran MW 70000 is used for drug delivery because TRITC maintains stability over a wide pH range (i.e., pH 2-11) and exhibits photobleaching resistance .
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2
2 Cited Publications
Cat. No.: HY-158082
Synonyms: Tetramethyl rhodamine isothiocyanate glucan, MW 4000
TRITC-dextran MW 4000 (Tetramethyl rhodamine isothiocyanate glucan, MW 4000) is a fluorescent dye, with the molecular weight of 4 kD. TRITC-dextran MW 4000 exhibits an excitation wavelength of 555 nm. TRITC-dextran MW 4000 is vessel penetrate, which could label blood plasma to visualize the vasculature. TRITC-dextran MW 4000 is utilized in drug delivery for the stability of TRITC over a wide pH range (i.e. pH 2–11) and resistance to photo-bleaching .
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1
1 Cited Publications
Cat. No.: HY-139413
CAS No.: 9041-22-9
Purity:  99.00%
β-D-glucan is a natural non-digestible polysaccharide and high biocompatibility that can be selectively recognized by recognition receptors such as Dectin-1 and Toll-like receptors as well as being easily internalized by murine or human macrophages, which is likely to attribute to a target delivery . β-d-glucan is an enteric delivery vehicle for probiotics .
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1
1 Cited Publications
Cat. No.: HY-107126
CAS No.: 1207753-03-4
Purity:  99.83%
Synonyms: MK 3118; SCY-078
Target:  

Fungal

Research Areas:  

Infection

Ibrexafungerp (MK 3118) is an orally active β-1,3-glucan synthesis inhibitor, with potential antifungal activity. Ibrexafungerp can be used for research of Candida and Aspergillus infections .
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1
1 Cited Publications
Cat. No.: HY-107126A
CAS No.: 1965291-08-0
Purity:  99.38%
Synonyms: MK 3118 citrate; SCY-078 citrate
Target:  

Fungal

Research Areas:  

Infection

Ibrexafungerp citrate (MK 3118 citrate) is an orally active β-1,3-glucan synthesis inhibitor, with potential antifungal activity. Ibrexafungerp citrate is an investigational agent for the treatment of Candida and Aspergillus infections .
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1
1 Cited Publications
Cat. No.: HY-N6924
CAS No.: 80930-74-1
Zingibroside R1 is an orally active triterpene saponin with multiple biological activities including antioxidant, anti-inflammatory, antiviral, and metabolic regulatory properties. Zingibroside R1 reduces the expression of PIN family members, inhibits the expression of PLT1/PLT2, WOX5, SHR, and SCR, disrupts auxin transport and distribution, triggers plant ROS responses, and inhibits root growth. Zingibroside R1 extends the lifespan of Caenorhabditis elegans, enhances its heat stress resistance, and improves its motor ability. Hydrogel derivatives of Zingibroside R1 inhibit the proliferation of Candida albicans by binding to its β-1,3-glucan and exhibit antifungal activity. Zingibroside R1 inhibits GLUT1-mediated uptake and alleviates liver injury. Zingibroside R1 can be used in research related to neurodegenerative diseases, vulvovaginal candidiasis, acute liver injury, Ehrlich ascites tumor and HIV-1 infection .
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1
1 Cited Publications
Cat. No.: HY-134655
CAS No.: 384376-42-5
Purity:  99.14%
Target:  

Fungal

Research Areas:  

Infection Inflammation/Immunology

D75-4590, a pyridobenzimidazole derivative and a β-1,6-glucan synthesis inhibitor, possesses antifungal activity .
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1
1 Cited Publications
Cat. No.: HY-P70101
Purity:  ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: rHuC-type lectin domain family 7 member A/Dectin-1, Fc; Beta-glucan receptor; BGR; CD369; CLEC7A; CLECSF12; CLECSF12DC-associated C-type lectin 1; Dectin1; Dectin-1; DECTIN1CANDF4
Species:  
Source:  
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Cat. No.: HY-134816
CAS No.: 9012-72-0
Purity:  ≥96.0%
D-Glucan is an orally effective Dectin-1 receptor immune activator with antioxidant properties (reducing TNF-α). D-Glucan activates macrophages and neutrophils to scavenge free radicals, inhibit oxidative stress and inflammatory responses, and improve insulin sensitivity. D-Glucan promotes glycolysis by enhancing the activity of the antioxidant enzyme glutathione, inhibiting gluconeogenesis and activating GK. D-Glucan can be used in the research of liver damage protection (antagonizing Acetaminophen (HY-66005) toxicity), radiation protection (synergistic with vitamin E) and diabetes (improving glucose metabolism) .
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Cat. No.: HY-E70013
CAS No.: 37288-51-0
Synonyms: endo-1,3:1,4-β-D-glucanase
Target:  

Glycosidase

Research Areas:  

Metabolic Disease

Lichenase, Microorganism (endo-1,3:1,4-β-D-Glucanase) is a specific, endo-(1-3),(1-4)-β-D-glucan 4-glucanohydrolase. Lichenase, Microorganism solubilizes β-glucans from cereal grains and gives gluco-oligosaccharides (GOS). Lichenase, Microorganism can be used in the degradation of polysaccharides in the cell walls .
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Cat. No.: HY-W050145
CAS No.: 498-07-7
Synonyms: 1,6-Anhydro-β-D-glucopyranose; 1,6-Anhydro-β-D-glucose
Levoglucosan (1,6-Anhydro-β-D-glucopyranose) is an anhydrosugar produced through glucan pyrolysis and is widely found in nature .
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Cat. No.: HY-P3004
CAS No.: 9025-37-0
Synonyms: Lyticase
Research Areas:  

Infection

Endo-1,3-β-glucanase (Lyticase) is an endoenzyme that can specifically cleave β-1,3-glycosidic bonds. Endo-1,3-β-glucanase recognizes and binds to β-1,3-glucan chains, catalyzing the cleavage of glycosidic bonds and hydrolyzing polysaccharides into oligosaccharides. Endo-1,3-β-glucanase eliminates vaginal Candida. Endo-1,3-β-glucanase can be used in the study of recurrent Candida vaginitis .
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Cat. No.: HY-147295
CAS No.: 53238-80-5
Synonyms: BTH 1677; Imprime PGG
Odetiglucan is a novel β-glucan that is a potent immunostimulant and a Dectin-1 (CLEC7A) agonist. Odetiglucan activates innate immune effector cells and triggers a coordinated anti-cancer immune response .
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Cat. No.: HY-165126
CAS No.: 9050-67-3
Synonyms: SPG
Schizophyllan (SPG) is an orally active extracellular β-glucan produced by the fungus Schizophyllum commune. Schizophyllan improves mitochondrial function and protects against metabolic liver injury by activating the SIRT3 pathway. Schizophyllan inhibits osteoclastogenesis and promotes osteoblast differentiation by suppressing the phosphorylation of JNK/p38, as well as downregulating PGC1β/PPARγ, c-Fos and NFATc1. Recognized via Dectin-1, schizophyllan enables precise delivery of oligonucleotide drugs and antigens to antigen-presenting cells, thus holding great potential in the treatment of inflammatory diseases and vaccine development .
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