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  3. Fluorescent Dye
  4. TRITC-dextran, MW 70000

TRITC-dextran, MW 70000  (Synonyms: Tetramethyl rhodamine isothiocyanate glucan, MW 70000)

Cat. No.: HY-158082C
COA
SDS
Handling Instructions Technical Support

TRITC-dextran MW 70000 (Tetramethyl rhodamine isothiocyanate glucan, MW 70000) is a fluorescent dye with a molecular weight of 70 kD. The excitation wavelength of TRITC-dextran MW 70000 is 555 nm, and its emission wavelength is 570 nm. TRITC-dextran MW 70000 is used for drug delivery because TRITC maintains stability over a wide pH range (i.e., pH 2-11) and exhibits photobleaching resistance.

For research use only. We do not sell to patients.

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Customer Review

Based on 2 publication(s) in Google Scholar

Other Forms of TRITC-dextran, MW 70000:

TRITC-dextran, MW 70000 Related Antibodies

Top Publications Citing Use of Products
Bio/Physico-chemical Assay

    TRITC-dextran, MW 70000 purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Aug 18:e08613.  [Abstract]

    TRITC-dextran, MW 70000 (TMR‐Dextran; 20 ng/mL; 100 µL;0, 30, 60, and 120 min) in HUVEC monolayers treated with indicated sEVs. The permeability of HUVEC monolayers to TRITC-dextran, MW 70000 (TMR‐Dextran; 20 ng/mL; 100 µL;0, 30, 60, and 120 min) increased after exposure to CLTB‐NC‐sEVs and CLTB‐OE‐sEVs.

    TRITC-dextran, MW 70000 purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Aug 18:e08613.  [Abstract]

    sEV-CLTB reduced TMR-dextran leakage. TRITC-dextran, MW 70000 (TMR‐Dextran; 20 ng/mL; 100 µL;0, 30, 60, and 120 min) permeability assay measuring vascular leakage in HUVECs. Fluorescence intensity in the lower chamber was quantified.

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    Description

    TRITC-dextran MW 70000 (Tetramethyl rhodamine isothiocyanate glucan, MW 70000) is a fluorescent dye with a molecular weight of 70 kD. The excitation wavelength of TRITC-dextran MW 70000 is 555 nm, and its emission wavelength is 570 nm. TRITC-dextran MW 70000 is used for drug delivery because TRITC maintains stability over a wide pH range (i.e., pH 2-11) and exhibits photobleaching resistance[1].

    In Vitro

    Paracellular Permeability Assay[1]
    1. Add TRITC-dextran MW 70000 (20 mg/mL, 100 μL) to the basal medium in the upper chamber of a transwell (pore size 0.4 μm).
    2. Collect the medium from the lower transwell chamber at 0, 30, 60, and 120 minutes.
    3. Measure the fluorescence signal (Ex=544 nm, Em=570 nm).
    4. Calculate the concentration of TRITC-dextran MW 70000 based on the fluorescence intensity.
    5. Calculate the permeability rate.

    MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

    TRITC-dextran, MW 70000 Related Antibodies
    Molecular Weight

    70000.00

    Appearance

    Solid

    Color

    Purple to purplish red

    SMILES

    [TRITC-dextran, MW 70000]
    Shipping

    Room temperature in continental US; may vary elsewhere.
    Storage

    4°C, protect from light

    *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

    Solvent & Solubility
    In Vitro: 

    H2O : 50 mg/mL (0.71 mM; Need ultrasonic)

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    Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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    Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

    This equation is commonly abbreviated as: C1V1 = C2V2

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    In Vivo Dissolution Calculator
    Please enter the basic information of animal experiments:

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    Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
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    Working solution concentration: mg/mL
    This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
    The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
    Purity & Documentation

    SDS (251 KB)

    COA (241 KB)

    Handling Instructions (2659 KB)
    References
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    TRITC-dextran, MW 70000 Related Classifications

    Help & FAQs
    • Do most proteins show cross-species activity?

      Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

    Keywords:

    TRITC-dextran, MW 70000Tetramethyl rhodamine isothiocyanate glucan, MW 70000Fluorescent Dyehepatocellular carcinomaTRITC-dextrandextranvascular endothelial monolayer permeability probeInhibitorinhibitorinhibit

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