9012-72-0
Chemical Structure
Biological Activity: D-Glucan is an orally effective Dectin-1 receptor immune activator with antioxidant properties (reducing TNF-α). D-Glucan activates macrophages and neutrophils to scavenge free radicals, inhibit oxidative stress and inflammatory responses, and improve insulin sensitivity. D-Glucan promotes glycolysis by enhancing the activity of the antioxidant enzyme glutathione, inhibiting gluconeogenesis and activating GK. D-Glucan can be used in the research of liver damage protection (antagonizing Acetaminophen (HY-66005) toxicity), radiation protection (synergistic with vitamin E) and diabetes (improving glucose metabolism)[1][2][3][4].
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D-Glucan | 96.0% | D-Glucan is an orally effective Dectin-1 receptor immune activator with antioxidant properties (reducing TNF-α). D-Glucan activates macrophages and neutrophils to scavenge free radicals, inhibit oxidative stress and inflammatory responses, and improve insulin sensitivity. D-Glucan promotes glycolysis by enhancing the activity of the antioxidant enzyme glutathione, inhibiting gluconeogenesis and activating GK. D-Glucan can be used in the research of liver damage protection (antagonizing Acetaminophen (HY-66005) toxicity), radiation protection (synergistic with vitamin E) and diabetes (improving glucose metabolism). | ||||||||||||||||||||
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- [1]. Ljungman AG, et al. (1→3) -β-d-Glucan stimulates nitric oxide generation and cytokine mRNA expression in macrophages. Environ Toxicol Pharmacol. 1998 Jun 2;5 (4) :273-81. [Content Brief]
- [2]. Toklu HZ, et al. Acetaminophen-induced toxicity is prevented by beta-D-glucan treatment in mice. Eur J Pharmacol. 2006 Aug 14;543 (1-3) :133-40. [Content Brief]
- [3]. Tabeie F, et al. Radioprotective Effect of Beta D-Glucan and Vitamin E on Gamma Irradiated Mouse. J Clin Diagn Res. 2017 Feb;11 (2) :TC08-TC11. [Content Brief]
- [4]. Liu M, et al. The anti-diabetic activity of oat β-d-glucan in streptozotocin-nicotinamide induced diabetic mice. Int J Biol Macromol. 2016 Oct;91:1170-6. [Content Brief]
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