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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
36 Results for "
histone H2A
" in MedChemExpress (MCE) Product Catalog:
Products (36)
36 Results for "histone H2A" in MCE Product Catalog:
2
2 Cited Publications
Cat. No.: HY-18643
CAS No.: 1002789-86-7
Target:
Domaines de recherche:
TZ9 is a selective Rad6 inhibitor. TZ9 inhibits Rad6B-induced histone H2A ubiquitination, downregulates intracellular β-catenin, induces G2-M arrest and apoptosis, and inhibits the proliferation and migration of metastatic human breast cancer cells .
1
Cat. No.: HY-160924
Domaines de recherche:
MS147 is a VHL-based PROTAC degrader of BMI1 and RING1B (polycomb repressive complex 1 core components). MS147 directly binds EED and VHL E3 ligase, recruiting the ligase to the EED-BMI1/RING1B complex to induce time-dependent, ubiquitination-mediated degradation of BMI1 and RING1B. MS147 reduces histone H2A Lys119 mono-ubiquitination without altering histone H3 Lys27 tri-methylation and inhibits cancer cells proliferation. MS147 can be used for the research of cancer, such as chronic myelogenous leukemia and b-cell lymphoma .
Cat. No.: HY-P0324
CAS No.: 219552-69-9
Target:
Cat. No.: HY-163518
Target:
Domaines de recherche:
Antitumor agent-153 (compound 11b) is an optimized H2A histone ubiquitination inhibitor based on PRT4165 (HY-19817). Antitumor agent-153 inhibits the viability of human osteosarcoma U2OS cells and reduces histone H2A monoubiquitination, exhibiting anticancer activity .
Cat. No.: HY-P0324A
Target:
Cat. No.: HY-P76382
Pureté: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: H2AC25; histone H2A Type 3; Prev. HIST3H2A; H2A.W histone; Prev. H2AW; MGC3165; histone Cluster 3, H2A; H2A-Clustered histone 25; histone Cluster 3 H2A; H2A Clustered histone 25; histone 3, H2A
Species:
Human
Source:
E. coli
Cat. No.: HY-P810603
Synonyms: H2A histone family member X; H2A histone family member X; H2A.FX; H2A.X; H2A/x; H2AFX; H2AX; H2AX_HUMAN; histone H2A.X
Host:
Rabbit
Reactivity:
Cat. No.: HY-P72328
Pureté: ≥ 95%, as determined by reducing SDS-PAGE.
Synonyms: H2AC4; histone H2A Type 1-B/E; Prev. HIST1H2AB; histone H2A/M; Prev. H2AFM; HIST1H2AE; H2A/M; histone H2A/A; histone Cluster 1 H2A Family Member B; histone H2A.2; H2A histone Family, Member M; histone H2A; histone Cluster 1, H2Ab; H2AFA; H2A Clustered His
Species:
Human
Source:
E. coli
Cat. No.: HY-P83263A
Synonyms: histone H2A.2
Cat. No.: HY-P86519
Synonyms: HIST1H2AG; H2AFP; HIST1H2AI; H2AFC; HIST1H2AK; H2AFD; HIST1H2AL; H2AFI; HIST1H2AM; H2AFN; histone H2A type 1; H2A.1; histone H2A/p; HIST1H2AB; H2AFM; HIST1H2AE; H2AFA; histone H2A type 1-B/E; histone H2A.2; histone H2A/a; histone H2A/m; HIS
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
